Prostate cancer: open trials in Canada

129 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT07287150
A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer
Trial Treatment · Phase 2 · Hoffmann-La Roche
Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal · Jewish General Hospital, Montreal · Princess Margaret Cancer Centre, Toronto
Registry updated 2026-11-06
NCT06136624
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Cross Cancer Institute (Site 0332), Edmonton · Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre (Site 0328), Greenfield Park · Centre Hospitalier de l'Université de Montréal (Site 0326), Montreal · The Ottawa Hospital - General Campus-The Ottawa Hospital Cancer Centre (Site 0336), Ottawa · Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus (Site 0327), Québec · Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer (Site 0329), Sherbrooke · Sunnybrook Research Institute (Site 0331), Toronto · Princess Margaret Cancer Centre (Site 0330), Toronto
Registry updated 2026-11-05
NCT07114601
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Trial Treatment · Phase 1 · Eli Lilly and Company
Juravinski Cancer Centre, Hamilton · Lady Davis Institute for Medical Research Jewish General Hospital, Montreal · Princess Margaret Hospital, Toronto · Sunnybrook Health Sciences Centre, Toronto
Registry updated 2026-11-04
NCT07291557
PSMA-PET Directed Radiation Therapy for High-Risk Prostate Cancer
Trial Treatment · Phase 2 · AHS Cancer Control Alberta
Cross Cancer Institute, Edmonton
Registry updated 2026-11-04
NCT05800665
A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
Trial Treatment · Phase 1 · Genentech, Inc.
Princess Margaret Hospital, Toronto · British Columbia Cancer Agency, Vancouver
Registry updated 2026-11-03
NCT07164443
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Arthur J.E. Child Comprehensive Cancer Centre, Calgary · Lakeridge Health, Oshawa · CHU de Quebec-Universite Laval, Québec · Princess Margaret Hospital, Toronto · Sunnybrook Health Sciences Center, Toronto · BC Cancer - Vancouver, Vancouver
Registry updated 2026-11-03
NCT07225946
A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Centre de Recherche du CHUM, Montreal · The Ottawa Hospital Cancer Centre, Ottawa · CHU de Quebec-Universite Laval, Québec · Princess Margaret Cancer Centre, Toronto · British Columbia Cancer Agency, Vancouver · British Columbia Cancer Agency Vancouver Island Centre, Victoria
Registry updated 2026-11-03
NCT06629779
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
Trial Treatment · Phase 3 · Pfizer
Prostate Cancer Centre, Calgary · CIUSSS- saguenay-Lac-Saint-Jean, Chicoutimi · Cross Cancer Institute, Edmonton · QEII Health Sciences Centre, Victoria General Site, Halifax · Centre Hospitalier de l'Université de Montréal, Montreal · Lakeridge Health, Oshawa
Registry updated 2026-10-30
NCT07387263
Mainstreaming Genetics: Evaluation of a Digital Application to Scale and Spread Oncologist-initiated Genetic Testing
Trial Treatment · Unity Health Toronto
Mount Sinai Hospital, Toronto · Sunnybrook Hospital, Toronto
Registry updated 2026-10-30
NCT07288359
Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
Trial Treatment · Phase 1/2 · Novartis Pharmaceuticals
Toronto
Registry updated 2026-10-29
NCT07516210
Adaptive Radiotherapy for Safe Hypofractionation
Trial Treatment · Phase 2 · Centre hospitalier de l'Université de Montréal (CHUM)
Centre Hospitalier de l'Université de Montréal, Montreal
Registry updated 2026-10-29
NCT07332455
First-Time-in-Human Study of GSK5471713 in Adults With mCRPC
Trial Treatment · Phase 1/2 · GlaxoSmithKline
Montreal · Toronto
Registry updated 2026-10-28
NCT06172478
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Trial Treatment · Phase 2 · Daiichi Sankyo
Cross Cancer Institute, Edmonton · Sunnybrook Research Institute, Toronto · Princess Margaret Cancer Centre, Toronto · BC Cancer - Vancouver, Vancouver
Registry updated 2026-10-26
NCT05946213
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
Trial Treatment · Phase 3 · NRG Oncology
CHUM - Centre Hospitalier de l'Universite de Montreal, Montreal · The Research Institute of the McGill University Health Centre (MUHC), Montreal · CIUSSSEMTL-Hopital Maisonneuve-Rosemont, Montreal · Ottawa Hospital and Cancer Center-General Campus, Ottawa · CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ), Québec · Atlantic Health Sciences Corporation-Saint John Regional Hospital, Saint John · Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke · University Health Network, Princess Margaret Hospital, Toronto · Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto
Registry updated 2026-10-23
NCT07570979
A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer
Trial Treatment · Phase 1 · Novartis Pharmaceuticals
Montreal · Toronto
Registry updated 2026-10-23
NCT07535905
Clinical Trial to Observe the Effects of Tamoxifen on Testosterone Recovery in Medically Castrated Prostate Cancer Patients
Trial Treatment · Phase 2 · University Health Network, Toronto
University Health Network - Princess Margaret Cancer Center, Toronto
Registry updated 2026-10-22
NCT05939414
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Calgary · Halifax · London · Montreal · Ottawa · Québec · Toronto
Registry updated 2026-10-21
NCT06136650
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
BC Cancer Abbotsford-Clinical Trials Unit (Site 0287), Abbotsford British Columbia · Cross Cancer Institute (Site 0281), Edmonton · Trillium Health Partners - Credit Valley Hospital (Site 0289), Mississauga · Centre Hospitalier de l'Université de Montréal (Site 0276), Montreal · The Ottawa Hospital - General Campus (Site 0286), Ottawa · Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus (Site 0277), Québec · Sunnybrook Research Institute (Site 0285), Toronto
Registry updated 2026-10-20
NCT06508567
Salvage MR-guided High-Dose-Rate Brachytherapy for Prostate Bed Recurrence After Radiotherapy in the PSMA PET Scan Era
Trial Treatment · University Health Network, Toronto
Princess Margaret Cancer Centre, Toronto
Registry updated 2026-10-20
NCT07213674
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
Trial Treatment · Phase 3 · Amgen
Sir Mortimer B Davis - Jewish General Hospital, Montreal · Centre de recherche du Centre hospitalier de l'Université de Montréal, Montreal · CIUSSS de L'Estrie - CHUS - Hopital Fleurimont, Sherbrooke · Sunnybrook Research Institute Sunnybrook Health Sciences Centre, Toronto
Registry updated 2026-10-20
NCT07611110
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
Trial Treatment · Phase 3 · AstraZeneca
Edmonton · Halifax · Hamilton · Montreal · Toronto
Registry updated 2026-10-19
NCT07711002
Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05)
Trial Treatment · Phase 3 · AstraZeneca
Abbotsford British Columbia · Brampton · Calgary · Edmonton · Greenfield Park · Kitchener · Montreal · North York · Ottawa · Saint-Jérôme · Saskatoon · Toronto · Windsor
Registry updated 2026-10-15
NCT06952803
A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
Trial Treatment · Phase 3 · AstraZeneca
Abbotsford British Columbia · Barrie · Brampton · Calgary · Chicoutimi · London · Montreal · Saskatoon · Toronto · Vancouver
Registry updated 2026-10-14
NCT07028853
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Trial Treatment · Phase 3 · Pfizer
Prostate Cancer Centre, Calgary · Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre, Greenfield Park · Centre of Applied Urology Research/Nova Scotia Health Authority, Halifax · Jewish General Hospital, Montreal · Centre Hospitalier de l'Université de Montréal, Montreal · Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus, Québec · Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer, Sherbrooke · Diex Recherche Trois-Rivieres, Trois-Rivières
Registry updated 2026-10-14
NCT06654336
Study of Recurrence-directed Therapy (RDT) With or Without Androgen-Deprivation Therapy (ADT) In Patients With Radio-recurrent Oligo-metastatic Hormone/Castrate Sensitive Prostate Cancer (romCSPC)
Trial Treatment · Phase 2 · Ontario Clinical Oncology Group (OCOG)
Juravinski Cancer Centre, Hamilton · McGill University Health Centre (MUHC) - Glen Site, Montreal · Jewish General Hospital, Montreal · The Ottawa Hospital Regional Cancer Centre, Ottawa · University Health Network - Princess Margaret Cancer Centre, Toronto
Registry updated 2026-10-13

All Prostate cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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