Prostate cancer trials in Canada

In Canada 129 Also abroad 1481

129 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)
Where
Montreal, Sherbrooke, Toronto, Vancouver
Age
18 years and over
People
360 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06863272 · EU 2024-516036-94-00
Phase 1/2Taking people
An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)
Where
Halifax
Age
18 years and over
People
188 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07206056 · EU 2025-521880-10-00
Phase 2Taking people
Comparing Moderately and Ultra Hypofractionated Radiation Treatments for Post-operative Prostate Cancer
Where
London, Toronto
Age
18 years and over
People
204
Run by
University Health Network, Toronto
See details and how to joinNCT06409910
Phase 1/2Taking people
A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer
Where
Montreal, Toronto
Age
18 years and over
People
85 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06990880 · EU 2025-521581-10-00
No phaseTaking people
Focal Versus Whole Gland High Dose-Rate Brachytherapy (HDR-BT) Boost to External Beam Radiotherapy in Localized Prostate Cancer: A Phase 2 Randomized Trial
Where
London
Age
18 years and over
People
58
Run by
Joelle Helou
See details and how to joinNCT07300566
Phase 3Taking people
A Study of Risvutatug Rezetecan in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) [EMBOLD Prostate-302]
Where
Montreal
Age
18 years and over
People
684 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07802704 · EU 2026-525558-13-00
Phase 1/2Taking people
TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Where
Montreal
Age
18 years and over
People
181 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07190300 · EU 2025-521873-15-00
Phase 2Not yet taking people in Canada
Molecular Imaging Informed Radiation Dose Escalation to Sites of Recurrent Disease and De-escalation to Uninvolved Areas in Salvage Radiotherapy Using SBRT for Prostate Cancer to Reduce Treatment Toxicity
Where
Toronto
Age
18 years and over
People
50
Run by
University Health Network, Toronto
See details and how to joinNCT07515651
Phase 3Taking people
Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.
Where
Edmonton, Montreal, Toronto, Vancouver
Age
50 years to 70 years
People
1,284 worldwide
Run by
University of Alberta
See details and how to joinNCT06626022
Phase 1Taking people
A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors
Where
Ottawa, Toronto
Age
18 years and over
People
83 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07277270 · EU 2025-522274-37-00
No phaseTaking people
Micro-ultrasound-Guided Focal Laser Ablation for Intermediate-Risk Prostate Cancer: Safety & Effectiveness
Where
Toronto
Age
40 years to 85 years
People
7
Run by
University Health Network, Toronto
See details and how to joinNCT07339943
No phaseNot yet taking people in Canada
Evaluation of a Prostate-Targeted PET Imaging System (P-PET) for Detecting Prostate Cancer
Where
London
People
25
Run by
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
See details and how to joinNCT07510906
Phase 3Taking people
18F-PSMA-1007 PET/CT in Prostate Cancer - Access Trial 2022 to 2028
Where
Edmonton
Age
18 years and over
People
2,800
Run by
University of Alberta
See details and how to joinNCT05520255
Phase 2Not yet taking people in Canada
Clinical Trial to Test Efficacy of Targeting Hypoxia Combined With ARSI After First-line ARSI Therapy for Castrate Resistant Prostate Cancer
Where
Toronto
Age
18 years and over
People
35
Run by
University Health Network, Toronto
See details and how to joinNCT06836726
Phase 2Taking people
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
Where
Montreal, Québec, Toronto
Age
18 years to 130 years
People
454 worldwide
Run by
AstraZeneca
See details and how to joinNCT05489211 · EU 2023-509436-26-00
Phase 1Taking people
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors
Where
Montreal
Age
18 years to 100 years
People
116 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07006727 · EU 2024-519111-34-00
Phase 2Taking people
Adaptive Versus Non-adaptive Radiotherapy and 2 Bladder Filling Instructions for Patients With Intermediate or High Risk Localized Prostate Cancer (ARP)
Where
Vancouver
Age
18 years and over
People
104
Run by
Scott Tyldesley
See details and how to joinNCT06678126
Phase 2Taking people
Radiotherapy to Consolidate Systemic Response in Metastatic Prostate Cancer (ANCHOR-Prostate)
Where
Montreal
People
80
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT05457699
Phase 2Taking people
Radiation Treatment of the Prostate That is Specially Adjusted for Each Person
Where
Lethbridge
Age
18 years and over
People
50
Run by
AHS Cancer Control Alberta
See details and how to joinNCT07578519
No phaseTaking people
Prostate Active Surveillance Study
Where
Vancouver
Age
21 years and over
People
3,000 worldwide
Run by
University of Washington
See details and how to joinNCT00756665
Phase 1/2Taking people
A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer
Where
Québec, Toronto
Age
18 years and over
People
52 worldwide
Run by
AstraZeneca
See details and how to joinNCT07192614 · EU 2025-520626-37-00
Phase 2Taking people
External Beam and Radioligand Radiotherapy for mCRPC
Where
Montreal
People
120
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT07354594
No phaseNot yet taking people in Canada
CEST for Prostate Biopsy
Where
Toronto
Age
18 years and over
People
20
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07785024
Phase 3Not yet taking people in Canada
ADT De-escalation in Selected High-Risk Prostate Cancer Patients (ADaPPt Trial) a GROUQ Led PCS Study (PCS XIV)
Where
Montreal
Age
18 years and over
People
600
Run by
Dr. Tamim Niazi
See details and how to joinNCT07777263
Phase 2Taking people
Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
Where
London, Ottawa, Toronto, Vancouver
Age
18 years and over
People
315 worldwide
Run by
University of British Columbia
See details and how to joinNCT04812366