Prostate cancer trials in Canada

In Canada 129 Also abroad 1481

129 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Continence, Sexual Function, Fitness and the Health of Men After Surgery for Prostate Cancer
Where
Edmonton
Age
18 years and over
People
106
Run by
University of Alberta
See details and how to joinNCT06072911
Phase 1Taking people
A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer
Where
Montreal, Toronto
Age
18 years and over
People
140 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06067841 · EU 2024-513987-24-00
No phaseNot yet taking people in Canada
68Ga-PSMA-11 PET/MRI for Selecting Men With Prostate Cancer for Focal Therapy
Where
Toronto
Age
18 years and over
People
8
Run by
University Health Network, Toronto
See details and how to joinNCT07747493
No phaseNot yet taking people in Canada
MICRO-ultrasound Guided Prostate SBRT
Where
London
Age
18 years and over
People
112
Run by
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
See details and how to joinNCT07737457
Phase 2Taking people
Duration of Androgen Receptor Pathway Inhibitor and ADT With Metastasis Directed Therapy in Oligometastatic Cancer of the Prostate (DIRECT)
Where
Toronto
Age
18 years to 100 years
People
352
Run by
University Health Network, Toronto
See details and how to joinNCT05404139
No phaseEnrolling by invitation
Clinical Utility of ClarityDX Prostate
Where
Calgary, Edmonton, Toronto, Vancouver, Winnipeg
Age
18 years and over
People
1,450
Run by
Nanostics
See details and how to joinNCT06678828
Phase 3Taking people
The Study of 177Lu-TLX591 Plus SOC Versus SOC Alone in Patients With mCRPC (ProstACT Global)
Where
Burnaby, Toronto
Age
18 years and over
People
520 worldwide
Run by
Telix Pharmaceuticals (Innovations) Pty Limited
See details and how to joinNCT06520345
Phase 4Taking people
Evaluating Dose Timing (Morning vs Evening) of Endocrine-based Therapies in Metastatic Breast and Prostate Cancers
Where
Kitchener, Ottawa, Saskatoon
Age
18 years and over
People
50
Run by
Ottawa Hospital Research Institute
See details and how to joinNCT07252726
Phase 3Taking people
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
Where
Edmonton, Greater Sudbury, Greenfield Park, Hamilton, Kingston, Kitchener, London, Mississauga, Montreal, Ottawa, Québec, Saint Catharines, Saint John, Saskatoon, Toronto, Vancouver, Winnipeg
Age
18 years and over
People
830 worldwide
Run by
Canadian Cancer Trials Group
See details and how to joinNCT06592924
Phase 1Taking people
First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)
Where
Edmonton, Hamilton, Montreal, Sherbrooke, Toronto, Vancouver
Age
18 years and over
People
198 worldwide
Run by
Bayer
See details and how to joinNCT06217822 · EU 2023-507486-26-00
Phase 2Taking people
Stereotactic Body Radiotherapy or Standard of Care for Prostate Oligoprogressive Cancer
Where
Toronto
Age
18 years to 100 years
People
75
Run by
University Health Network, Toronto
See details and how to joinNCT06927635
No phaseTaking people
Non-inferiority Study Comparing Salvage Pelvic Radiotherapy in 25 Fractions (62.5 Gy/25) Versus 20 Fractions (52.5 Gy/20) for Recurrent Prostate Cancer After Surgery.
Where
Gatineau, Montreal, Québec
Age
18 years and over
People
434
Run by
CHU de Quebec-Universite Laval
See details and how to joinNCT07483658
No phaseTaking people
Partial Prostate Salvage High Dose Rate Brachytherapy
Where
Kelowna
Age
45 years and over
People
30
Run by
British Columbia Cancer Agency
See details and how to joinNCT03246802
Phase 2Taking people
A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study
Where
Kelowna, Montreal, Toronto
Age
18 years and over
People
37 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT04641247 · EU 2023-506618-29-00
Phase 2Taking people
Phase II Randomized Trial of 2 Versus 5 Fraction Prostate Stereotactic Ablative Radiotherapy for Intermediate Risk Prostate Cancer
Where
Surrey, Victoria
Age
18 years and over
People
100
Run by
British Columbia Cancer Agency
See details and how to joinNCT06835725
No phaseTaking people
High-Dose-Rate Brachytherapy
Where
Toronto
Age
18 years and over
People
500
Run by
University Health Network, Toronto
See details and how to joinNCT00913939
No phaseTaking people
A SMART Design to Optimize the Delivery of TEMPO for Men With Prostate Cancer and Their Caregivers
Where
Montreal
Age
18 years and over
People
376
Run by
St. Mary's Research Center, Canada
See details and how to joinNCT06363266
No phaseTaking people
A Pan-Canadian, Investigator Initiated Clinical Trial With Focal IRE Directed to Intermediate-Risk Prostate Cancer
Where
Toronto
Age
50 years and over
People
100
Run by
University Health Network, Toronto
See details and how to joinNCT06451445
No phaseTaking people
Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)
Where
Kingston, Ottawa, Toronto
Age
18 years and over
People
500
Run by
University Health Network, Toronto
See details and how to joinNCT05403177
Phase 1Taking people
Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
Where
Montreal, Toronto
Age
18 years and over
People
52 worldwide
Run by
Senhwa Biosciences, Inc.
See details and how to joinNCT04890613
No phaseTaking people
MRI Guided Focal Laser Ablation of Prostate Cancer
Where
Toronto
Age
40 years to 80 years
People
102
Run by
University Health Network, Toronto
See details and how to joinNCT03650595
No phaseTaking people
Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer
Where
Toronto
Age
18 years and over
People
100
Run by
University Health Network, Toronto
See details and how to joinNCT05313815
Phase 4Taking people
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
Where
Montreal
Age
18 years to 100 years
People
700 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05803941 · EU 2023-503208-94-00
Phase 2Taking people
PSMA-Guided Ablation of the Prostate
Where
Calgary, Edmonton, Toronto
Age
50 years and over
People
138
Run by
University of Alberta
See details and how to joinNCT06003556
Phase 3Taking people
Is Adaptive SBRT for Prostate vs Image-guided Radiotherapy a True Evolution (ASPIRE)
Where
Toronto
Age
18 years and over
People
320
Run by
University Health Network, Toronto
See details and how to joinNCT06825091