Prostate cancer trials in United States

In United States 655 Also abroad 1490

655 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance
Where
San Francisco
Age
18 years and over
People
60
Run by
University of California, San Francisco
See details and how to joinNCT03933670
Phase 1Enrolling by invitation
Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer
Where
Boston
Age
22 years and over
People
35
Run by
Brigham and Women's Hospital
See details and how to joinNCT04399876
No phaseTaking people
Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study
Where
Boston, Chicago, Duarte, Philadelphia, Portland, San Antonio, San Francisco, Seattle
Age
40 years and over
People
450
Run by
University of Washington
See details and how to joinNCT04472338
No phaseTaking people
Flotufolastat F 18 PET in Men With Very Low PSA Recurrence
Where
Boston
Age
18 years and over
People
50
Run by
Massachusetts General Hospital
See details and how to joinNCT06862856
Phase 2Taking people
Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC
Where
Tampa
Age
18 years and over
People
12
Run by
H. Lee Moffitt Cancer Center and Research Institute
See details and how to joinNCT07476001
Phase 1/2Not yet taking people in United States
dMD-002 Pilot Study in Patients With Cavernous Nerve Injury Following Radical Prostatectomy
Where
New York
Age
40 years to 74 years
People
30
Run by
Mochida Medical USA, Inc.
See details and how to joinNCT07564102
Phase 1/2Taking people
Anti-tumour Activity of (177Lu) rhPSMA-10.1 Injection
Where
Atlanta, Miami, New York, Omaha
Age
18 years and over
People
82 worldwide
Run by
Blue Earth Therapeutics Ltd
See details and how to joinNCT05413850 · EU 2024-511537-35-00
Phase 4Taking people
Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men With Localized Prostate Cancer on Active Surveillance
Where
Buffalo
Age
18 years and over
People
600
Run by
Roswell Park Cancer Institute
See details and how to joinNCT06733350
Phase 1/2Taking people
COAST Therapy in Advanced Solid Tumors and Prostate Cancer
Where
Charleston
Age
18 years and over
People
76
Run by
Medical University of South Carolina
See details and how to joinNCT05036226
Phase 1Taking people
Brodalumab in the Treatment of Immune-Related Adverse Events
Where
New York
Age
18 years and over
People
11
Run by
Brian Henick, MD
See details and how to joinNCT06673329
Phase 1/2Enrolling by invitation
Continuation Protocol for ZEN003694 in Patients Experiencing Clinical Benefit While Enrolled in a ZEN003694 Protocol
Where
Portland, San Francisco
Age
18 years and over
People
40
Run by
Zenith Epigenetics
See details and how to joinNCT04145375
Phase 2Taking people
ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer
Where
Ann Arbor, Asheville, Austin, Baton Rouge, Columbia, Fairfax, Lakewood, Los Angeles, Margate, Nashville, New York, Plantation, Portland, San Francisco, Seattle, Whittier
Age
18 years and over
People
200 worldwide
Run by
Zenith Epigenetics
See details and how to joinNCT04986423
No phaseTaking people
Internet-Based Lifestyle Intervention to Eradicate Obese Frailty in Prostate Cancer Survivors, iLIVE
Where
Portland
Age
18 years and over
People
250
Run by
OHSU Knight Cancer Institute
See details and how to joinNCT06011499
No phaseTaking people
Nutrition and Exercise Interventions for Androgen Deprivation Therapy-Induced Obese Frailty in Elderly and Non-Elderly Survivors of Advanced Prostate Cancer
Where
Buffalo
Age
18 years and over
People
50
Run by
Roswell Park Cancer Institute
See details and how to joinNCT03880422
No phaseTaking people
MRI-Guided Cryoablation for Focal Native Prostate Cancer
Where
Rochester
Age
30 years to 100 years
People
100
Run by
Mayo Clinic
See details and how to joinNCT04797039
Phase 1/2Taking people
64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)
Where
Grand Rapids, New York, Omaha, River Ridge, Rochester, Stanford, St Louis
Age
18 years and over
People
54
Run by
Clarity Pharmaceuticals Ltd
See details and how to joinNCT04868604
No phaseTaking people
GET FIT Together: Testing a Socially Enhanced Exercise Program in Older Men With Prostate Cancer
Where
Portland
Age
65 years and over
People
150
Run by
OHSU Knight Cancer Institute
See details and how to joinNCT07504835
Phase 2Not yet taking people in United States
Utilization of Flotufolastat 18F PET for Post-Focal Therapy Prostate Cancer Evaluation
Where
Orange
Age
18 years and over
People
60
Run by
University of California, Irvine
See details and how to joinNCT07568756
Phase 1/2Taking people
A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer
Where
Baltimore, Buffalo, Charlotte, Columbus, Houston, Louisville, Milwaukee, New Brunswick, New Haven, Palo Alto, Philadelphia
Age
18 years and over
People
228
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT05125016 · EU 2022-502130-17-00
Phase 1/2Taking people
Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Where
Ann Arbor, Chicago, Detroit
Age
18 years and over
People
20
Run by
University of Michigan Rogel Cancer Center
See details and how to joinNCT06616155
Phase 2Taking people
Axelopran for Advanced Cancer in Patients Receiving Opioids
Where
Saint Louis Park, Saint Paul
Age
18 years and over
People
34
Run by
HealthPartners Institute
See details and how to joinNCT07354919
No phaseTaking people
Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr
Where
Cleveland, Los Angeles, New York, San Francisco
Age
18 years and over
People
200
Run by
Weill Medical College of Cornell University
See details and how to joinNCT05948657
No phaseTaking people
Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)
Where
Charlottesville
Age
18 years and over
People
24
Run by
Paul Viscuse
See details and how to joinNCT06429813
Phase 1/2Taking people
Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System
Where
New York
Age
18 years and over
People
66 worldwide
Run by
SpectraCure AB
See details and how to joinNCT03067051
Phase 1/2Taking people
Photodynamic Therapy of Primary Localized Prostate Cancer With the SpectraCure P18 System
Where
New York
Age
18 years and over
People
43 worldwide
Run by
SpectraCure AB
See details and how to joinNCT06807359