Prostate cancer trials in United States

In United States 655 Also abroad 1490

655 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer
Where
Baltimore
Age
18 years and over
People
58
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT06616597
Phase 2Taking people
The University of Miami Adapt (UAdapt) Trial
Where
Miami
Age
35 years to 85 years
People
130
Run by
University of Miami
See details and how to joinNCT06111313
No phaseTaking people
Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer
Where
Atlanta
Age
18 years and over
People
30
Run by
Emory University
See details and how to joinNCT04725903
Phase 2Taking people
Image-guided, Tumor-focused Radiotherapy Treatment in Intermediate and High-risk Prostate Cancer
Where
La Jolla
Age
18 years and over
People
150
Run by
University of California, San Diego
See details and how to joinNCT06990542
No phaseTaking people
PSMA PET for Surveillance After Focal Therapy
Where
Chicago
Age
18 years and over
People
62
Run by
University of Chicago
See details and how to joinNCT07115914
Phase 1/2Taking people
Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors
Where
East Brunswick, Fairfax, Grand Rapids, Irving, San Antonio, San Francisco, West Valley City
Age
18 years and over
People
150
Run by
MBrace Therapeutics
See details and how to joinNCT07145255
No phaseTaking people
Screening and Staging of Benign vs Malignant Pelvic Abnormalities
Where
Rochester
Age
18 years and over
People
60
Run by
Mayo Clinic
See details and how to joinNCT07407959
Early phase 1Taking people
Image-guided Focal Brachytherapy Utilizing Combined 18F-DCFPyl PET/CT
Where
Baltimore
Age
18 years to 100 years
People
20
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT03861676
Phase 1Taking people
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
Where
Baltimore, Chicago, Dallas, Durham, Hackensack, Houston, Lexington, Los Angeles, Miami, Nashville, New York, Philadelphia, Sacramento, San Francisco, Scottsdale, Seattle, Tucson
Age
18 years and over
People
90
Run by
Clasp Therapeutics, Inc.
See details and how to joinNCT06778863
No phaseTaking people
AVI Didactic Experience for Latinx Patient Treatment Adherence and Non-English Speaker Trial Enrollment Study in Rad Onc
Where
Miami Beach, New York
Age
18 years and over
People
194
Run by
Columbia University
See details and how to joinNCT05351424
Phase 2Taking people
Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)
Where
Baltimore
Age
18 years and over
People
47 worldwide
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT04704505
Phase 2Taking people
Hypofractionated WPPT With HDR Boost
Where
Philadelphia
Age
18 years and over
People
30
Run by
Abramson Cancer Center at Penn Medicine
See details and how to joinNCT06591819
Phase 2Taking people
Fezolinetant for Treating Hot Flashes in Men With Prostate Cancer
Where
Burlington
Age
18 years and over
People
32
Run by
University of Vermont
See details and how to joinNCT06972875
Phase 2Taking people
Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors
Where
Aurora, Missoula
Age
18 years to 89 years
People
134
Run by
University of Colorado, Denver
See details and how to joinNCT07001241
No phaseTaking people
Image-Guidance and Online Adaptation With Stereotactic Body Radiation Therapy for the Treatment of Localized Prostate Cancer, MANTICORE Trial
Where
Los Angeles
Age
18 years and over
People
186
Run by
Jonsson Comprehensive Cancer Center
See details and how to joinNCT07276438
Phase 2Taking people
Hypofractionated Radiotherapy With a Focal Microboost for High-Risk and Locally Advanced Prostate Cancer
Where
Charleston
Age
18 years and over
People
46
Run by
Medical University of South Carolina
See details and how to joinNCT07325721
Phase 1Taking people
A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
Where
Albuquerque, Anaheim, Bala-Cynwyd, Bethesda, Charlottesville, Dallas, Durham, Fort Wayne, Houston, Jeffersonville, Middleburg Heights, Morristown, Myrtle Beach, Nashville, Omaha, San Antonio, Santa Rosa, Tacoma, Tampa, Toledo, Towson, Tucson, Wichita
Age
18 years and over
People
174 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT04729114
Early phase 1Taking people
HCQ in Resectable Localized Prostate Cancer
Where
Lebanon
Age
18 years and over
People
20
Run by
Lionel.D.Lewis, MD
See details and how to joinNCT06408298
Phase 3Taking people
Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial
Where
Buffalo
Age
1 year and over
People
800
Run by
Roswell Park Cancer Institute
See details and how to joinNCT06563388
No phaseTaking people
Men With Prostate Cancer: Optimizing Wellness by Enhanced Relief From Hot Flashes With Acupuncture
Where
Fairfax
Age
18 years and over
People
24
Run by
Inova Health Care Services
See details and how to joinNCT07335224
Early phase 1Taking people
A Platform Study of Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer
Where
Los Angeles
Age
18 years and over
People
20
Run by
Edwin Posadas, MD
See details and how to joinNCT06888102
No phaseTaking people
Physician- and Patient-based Barriers to NGS Testing
Where
Baltimore
Age
18 years and over
People
256
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT07209176
No phaseTaking people
Prostate Ablation Registry and Database for Information, Surveillance, and Evaluation (PARADISE)
Where
Cincinnati, Hyde Park
Age
22 years and over
People
3,000
Run by
University of Chicago
See details and how to joinNCT06705803
No phaseTaking people
Improving Health Literacy in African-American Prostate Cancer Patients
Where
Atlanta
Age
25 years to 100 years
People
210
Run by
Emory University
See details and how to joinNCT03322891
Phase 2Taking people
Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation
Where
Aberdeen, Anaconda, Anchorage, Arroyo Grande, Baker City, Bardstown, Bellingham, Bend, Billings, Boise, Bozeman, Bremerton, Burbank, Caldwell, Carmichael, Centralia, Cincinnati, Clackamas, Cody, Coeur d'Alene, Colorado Springs, Coos Bay, Corbin, Council Bluffs, Denver, Derby, Duarte, Durango, Edmonds, Elk Grove, Emmett, Evanston, Everett, Fairfield, Fruitland, Glastonbury, Glenview, Great Falls, Greenwich, Guilford, Hartford, Highland Park, Irvine, Issaquah, Kalispell, Kearney, Kennewick, Lacey, Lakewood, Lexington, Lincoln, Littleton, London, Longmont, Longview, Meridian, Metairie, Middletown, Missoula, Mount Sterling, Nampa, Napa, Newberg, New Haven, New Orleans, North Haven, Oklahoma City, Omaha, Ontario, Oregon City, Papillion, Parker, Phoenix, Portland, Post Falls, Pueblo, Redmond, Rocklin, Sacramento, Sandpoint, San Luis Obispo, Santa Maria, Santa Rosa, Seattle, Sedro-Woolley, Shelton, Sheridan, Skokie, Stamford, Torrington, Trumbull, Twin Falls, Vancouver, Walla Walla, Waterbury, Waterford, Westerly, Woodland, Yelm
Age
18 years and over
People
44
Run by
SWOG Cancer Research Network
See details and how to joinNCT05806515