Sarcoma: open trials in France

71 open trials have a site in France. Registry data; only the trial team decides who can take part.

NCT06644755
First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
Trial Treatment · Phase 1 · Daiichi Sankyo
Centre Leon Berard, Lyon
Registry updated 2026-09-04
NCT07802847
Innovative and Cooperative Pathway Integrating Oncogeriatric, Pharmaceutical and Pharmacological Follow-up in Elderly Patients.
Trial Treatment · Phase 4 · Gustave Roussy, Cancer Campus, Grand Paris
Gustave Roussy, Villejuif
Registry updated 2026-09-03
2024-513033-21-00
Long-Term Follow-Up (LTFU) of Participants Treated with Adoptive Cell Therapies
Trial Treatment · Phase 1 · USWM Ct LLC
Centre Hospitalier Universitaire de Bordeaux, Pessac
Registry updated 2026-08-14
NCT06263231
A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
Trial Treatment · Phase 3 · Intensity Therapeutics, Inc.
Centre Leon Berard, Lyon · Centre Antoine Lacassagne, Nice Cedex 2 · Centre Hospitalier Universitaire de Poitiers, Poitiers · Institut Gustave Roussy, Villejuif
Registry updated 2026-08-11
2025-523997-18-00
A Study Evaluating the Efficacy and Safety of Risvutatug Rezetecan in Participants With Advanced Sarcomas (EMBOLD Sarcoma-202)
Trial Treatment · Phase 1/2 · Glaxosmithkline Research & Development Limited
Institut Bergonie, Bordeaux · Centre Leon Berard, Lyon · Institut Gustave Roussy, Villejuif
Registry updated 2026-07-27
NCT07507773
Assessment of the Long-term Efficacy of Moderately Hypofractionated Neoadjuvant Radiotherapy Soft Tissue Sarcoma in the Limbs or Trunk Wall
Trial Treatment · Phase 2 · Centre Oscar Lambret
Centre Oscar Lambret, Lille
Registry updated 2026-07-23
NCT07377747
Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma
Research · Australia and New Zealand Sarcoma Association
Institut Curie Hospital, Paris
Registry updated 2026-07-15
NCT04068155
Alpha Radiation Emitters Device (DaRT) for the Treatment of of Malignant Cutaneous Tumors
Trial Treatment · Alpha Tau Medical LTD.
CHU Grenoble Alpes, Grenoble · Centre Leon Berard, Lyon
Registry updated 2026-06-16
NCT06967961
Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers
Trial Treatment · Institut Claudius Regaud
Oncopole Claudius Regaud, IUCT-O, Toulouse
Registry updated 2026-06-15
NCT06476704
Study of Preoperative RAdiation Therapy With Concomitant Liposomal Transcrocetin (L-TC) in Soft tISsue Sarcomas
Trial Treatment · Phase 2 · Centre Paul Strauss
CGFL, Dijon · ICANS, Strasbourg
Registry updated 2026-06-04
NCT06022159
A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.
Trial Treatment · Phase 2 · Institut Claudius Regaud
Institut Bergonie, Bordeaux · Centre Oscar Lambret, Lille · CHU de Limoges, Limoges · Centre Leon Berard, Lyon · Institut Regional Du Cancer de Montpellier, Montpellier · Institut Curie, Paris · CHU de Poitiers, Poitiers · Institut de Cancérologie de l'Ouest, Saint-Herblain · CHU de Toulouse, Toulouse · IUCT-O, Toulouse · Institut Gustave Roussy, Villejuif
Registry updated 2026-06-02
NCT03093116
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Trial Treatment · Phase 1/2 · Turning Point Therapeutics, Inc.
Centr Georges Francois Leclerc, Dijon · Centre Hospitalier Universitaire Grenoble Alpes, Grenoble Cedex 9 · Centre Antoine Lacassagne, Nice Cedex 2 · Institut Gustave Roussy, Villejuif
Registry updated 2026-05-27
NCT06408441
The Epithelioid Hemangioendothelioma Registry of the European Reference Network on Rare Adult Solid Cancers (EURACAN)
Research · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Centre Oscar Lambret, Lille · Leon Berard Center, Lyon
Registry updated 2026-04-03
NCT05500391
Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring
Trial Treatment · Phase 2 · Centre Oscar Lambret
CHU Amiens, Amiens · Centre François Baclesse, Caen · Centre Oscar Lambret, Lille
Registry updated 2026-03-18
NCT06211257
Superiority Trial Evaluating Digitalized Information Media for Patients With Advanced Sarcomas Receiving Systemic Treatment.
Trial Treatment · Centre Oscar Lambret
Chu Jean Minjoz, Besançon · Centre Oscar Lambret, Lille · Centre Leon Berard, Lyon · Hôpital Pitié-Salpêtrière - AP-HP, Paris · CHU de Poitiers, Poitiers · Centre Eugène Marquis, Rennes · Institut de Cancérologie de l'Ouest, Saint-Herblain · Centre Paul Strauss, Strasbourg · Institut Claudius Regaud, Toulouse · Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy · Gustave Roussy, Villejuif
Registry updated 2026-03-18
NCT03624244
Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)
Trial Treatment · Phase 2 · Centre Leon Berard
CHU Besancon, Besancon Cedex · Institut Bergonie, Bordeaux · Centre Francois Baclesse, Caen Cedex 5 · Centre Jean Perrin, Clermont-Ferrand · Centre Oscar Lambret, Lille · Centre Hospitalier Et Universitaire De Limoges, Limoges Cedex 1 · Centre Leon Berard, Lyon · Centre Hospitalier Regional De Marseille, Marseille · Institut Paoli-Calmettes, Marseille · Institut Regional Du Cancer De Montpellier, Montpellier Cedex 5 · Centre Antoine Lacassagne, Nice Cedex 2 · Institut Curie, Paris · Assistance Publique Hopitaux de Paris, Paris · Assistance Publique Hopitaux De Paris, Paris Cedex 13 · Institut Godinot, Reims · Centre Henri Becquerel, Rouen Cedex · Hôpital privé de la Loire, Saint-Etienne · Institut De Cancerologie De L Ouest, Saint-Herblain Cedex · Centre Hospitalier Universitaire de Saint Etienne, Saint-Priest-en-Jarez · Centre Hospitalier Regional Universitaire De Tours, Tours Cedex 9 · Institut Gustave Roussy, Villejuif
Registry updated 2026-02-17
NCT04055220
Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas
Trial Treatment · Phase 3 · Centre Leon Berard
CHU Besançon, Besançon · Institut Bergonie, Bordeaux · University Of Bordeaux, Bordeaux Cedex · Centre Oscar Lambret, Lille · Centre Leon Berard, Lyon · Centre Hospitalier Regional De Marseille, Marseille · Institut Regional Du Cancer De Montpellier, Montpellier Cedex 5 · Institut Curie, Paris · Assistance Publique Hopitaux de Paris, Paris · Centre Hospitalier Universitaire de Poitiers, Poitiers · Centre Hospitalier Universitaire de Saint Etienne, Saint-Etienne · Institut De Cancerologie De L Ouest, Saint-Herblain Cedex · Centre Paul Strauss, STRASBOURG, Alsace · Les Hopitaux Universitaires De Strasbourg, Strasbourg Cedex 2 · Oncopole Claudius Regaud, Toulouse Cedex 9 · Institut de cancérologie de Lorraine, Vandoeuvre Les Nancy_ Cedex · Institut Gustave Roussy, Villejuif
Registry updated 2026-02-17
NCT04698785
Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients
Trial Treatment · Phase 2 · Centre Leon Berard
CHU Besançon, Besançon · Institut Bergonie, Bordeaux · Centre Georges François Leclerc, Dijon · Centre Oscar Lambret, Lille · Centre Leon Berard, Lyon · Hopital de la Timone, Marseille · ICM Val d'Aurelle, Montpellier · Hôtel Dieu - Nantes, Nantes · Hôpital Cochin, Paris · Institut Curie, Paris · Ico Rene Gauducheau, Saint-Herblain · CHU Saint Etienne, Saint-Priest-en-Jarez · CHRU Hôpital Hautepierre, Strasbourg · ICANS, Strasbourg · IUCT Oncopôle, Toulouse · Institut Gustave Roussy, Villejuif
Registry updated 2026-02-17
NCT03967834
Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group
Trial Treatment · Institut Claudius Regaud
Chu Besancon - Site Jean Minjoz, Besançon · Institut Bergonie, Bordeaux · Centre Jean Perrin, Clermont-Ferrand · Centre Georges François Leclerc, Dijon · Centre Oscar Lambret, Lille · Chu Dupuytren, Limoges · Centre Leon Berard, Lyon · Institut Paoli-Calmettes, Marseille · CHU de Marseille - Hôpital de la Timone, Marseille · Centre Antoine Lacassagne, Nice · Institut Curie, Paris · Hôpital Cochin - Site Port-Royal, Paris · CHU Poitiers, Poitiers · Institut Godinot, Reims · Centre Eugène Marquis, Rennes · Institut de Cancérologie de l'Ouest site René Gauducheau, Saint-Herblain · Hopitaux Universitaires de Strasbourg, Strasbourg · Institut Universitaire du Cancer Toulouse - Oncopole, Toulouse · Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy · Institut Gustave Roussy, Villejuif
Registry updated 2026-02-10
NCT07401355
Improved Management of Soft Tissue Sarcomas Patients With an Optimized and Innovative Sorting Technology for Circulating Tumor Cells
Trial Treatment · Centre Leon Berard
BRAHMI Mehdi, Lyon
Registry updated 2026-02-10
NCT05890781
Engineering Immune Organoids to Study Pediatric Cancer
Trial Treatment · Gustave Roussy, Cancer Campus, Grand Paris
Hôpital Necker, Paris · Gustave Roussy, Villejuif
Registry updated 2026-02-09
NCT03017573
Prospective Biobanking Study in Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)
Trial Treatment · Institut Curie
Institut Bergonie, Bordeaux · Centre Oscar Lambret, Lille · Centre Leon Berard, Lyon · Institut Curie, Paris · Institut Curie - Hôpital René Huguenin, Saint-Cloud · Institut de Cancérologie de Lorraine - Nancy, Vandœuvre-lès-Nancy
Registry updated 2026-02-03
NCT07192068
Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene.
Trial Treatment · Phase 2 · UNICANCER
Institut de Cancerologie de L'Ouest, Angers · Centre Hospitalier Simone Veil De Beauvais, Beauvais · Centre hospitalier Universitaire de Bordeaux, Bordeaux · Centre Hospitalier Régional et Universitaire de Brest, Brest · Centre Jean Perrin, Clermont Ferrand Cedex1 · Centr Georges Francois Leclerc, Dijon · Centre Leon Berard, Lyon · Centre Hospitalier Regional De Marseille, Marseille · Institut Paoli-Calmettes, Marseille · Centre Antoine Lacassagne, Nice Cedex 2 · Institut Curie, Paris · Assistance Publique Hopitaux de Paris, Paris · Centre Hospitalier Universitaire de Poitiers, Poitiers · Institut Godinot, Reims · Centre Hospitalier Universitaire de Saint Etienne, Saint-Priest-en-Jarez · Les Hopitaux Universitaires De Strasbourg, Strasbourg Cedex 2 · Oncopole Claudius Regaud, Toulouse Cedex 9 · Institut de cancérologie de Lorraine, Vandoeuvre Les Nancy_ Cedex · Institut Gustave Roussy, Villejuif
Registry updated 2025-12-19
NCT06333314
Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI
Trial Treatment · Phase 2 · UNICANCER
Institut de Cancerologie de L'Ouest, Angers · Institut du Cancer Avignon-Provence, Avignon · Chu Jean Minjoz, Besançon · CHU Morvan, Brest · Centre François Baclesse, Caen · Centre Jean Perrin, Clermont-Ferrand · CHU Henri Mondor, Créteil · Centre Georges François Leclerc, Dijon · Centre Leon Berard, Lyon · Institut Paoli-Calmettes, Marseille · Hôpital la Timone, Marseille · Institut de cancérologie de Lorraine, Nancy · Hôpital Saint-Antoine, Paris · Institut Mutualiste Montsouris, Paris · CHU de Bordeaux Hopital Haut leveque, Pessac · CHU de Poitiers, Poitiers · Institut Jean Godinot, Reims · Centre Eugène Marquis, Rennes · CHU de Rouen, Rouen · Institut de Cancérologie de l'Ouest, Saint-Herblain · CHU de Toulouse - Hopital Rangueil, Toulouse · Gustave Roussy Grand Paris, Villejuif
Registry updated 2025-12-02
NCT05182164
Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas
Trial Treatment · Phase 2 · Institut Bergonié
Institut Bergonie, Bordeaux · Centr Georges Francois Leclerc, Dijon · Centre Leon Berard, Lyon · Institut Paoli-Calmettes, Marseille · Assistance Publique Hôpitaux de Marseille, Marseille · Hopital Cochin - Port Royal, PARIS · Institut De Cancerologie De L Ouest, St Herblain · Les Hopitaux Universitaires De Strasbourg, Strasbourg Cedex · Centre Hospitalier Universitaire De Toulouse, Toulouse Cedex 9 · Institut Gustave Roussy, Villejuif Cedex
Registry updated 2025-10-07

All Sarcoma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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