Sarcoma: open trials in United States

301 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT03016819
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)
Trial Treatment · Phase 3 · Advenchen Laboratories, LLC
University Of Michigan Comprehensive Cancer Center, Ann Arbor · University of Colorado Denver, Aurora · Northwestern University, Chicago · MD Anderson Cancer Center, Houston · Mayo Clinic- Jacksonville, Jacksonville · University of California, Los Angeles, Los Angeles · University of Miami - Sylvester Comprehensive Cancer Center, Miami · Vanderbilt University, Nashville · Columbia University Medical Center, New York · Thomas Jefferson Hospital - Sidney Kimmel Cancer Center, Philadelphia · Mayo Clinic - Arizona, Phoenix · University of Pittsburgh Medical Center, Pittsburgh · Mayo Clinic - Rochester, Rochester · Sarcoma Oncology Center, Santa Monica · UW Medicine-Seattle Cancer Care Alliance, Seattle · Stanford Medicine Cancer Institute, Stanford · Washington University St. Louis, St Louis
Registry updated 2026-02-25
NCT04354064
Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
Research · Washington University School of Medicine
Washington University School of Medicine, St Louis
Registry updated 2026-02-20
NCT04719156
Fluorescent Intra-operative Tumor Margin Examination
Trial Treatment · Phase 2 · Kurt Weiss
UPMC-Shadyside Hospital, Pittsburgh
Registry updated 2026-02-20
NCT06709495
Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas
Trial Treatment · Phase 1/2 · David S Shulman, MD
Dana-Farber Cancer Institute, Boston · Brigham and Women's Hospital, Boston · Boston Children's Hospital, Boston
Registry updated 2026-02-19
NCT07359911
Effect of A Multimodal Exercise Intervention on Chemotherapy Uptake in Newly Diagnosed Pediatric and AYA Sarcoma Patients
Trial Treatment · University of Miami
University of Miami, Miami
Registry updated 2026-02-18
NCT07148050
Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells
Trial Treatment · Phase 1 · Seattle Children's Hospital
Seattle Children's Hospital, Seattle
Registry updated 2026-02-17
NCT02677961
An Electronic Health Record (EHR)-Based Comprehensive Bone and Soft Tissue Tumor Registry
Research · Ohio State University Comprehensive Cancer Center
Ohio State University, Columbus
Registry updated 2026-02-11
NCT03458520
Pediatric PET/MR Image Registry
Research · Stanford University
Stanford University, School of Medicine, Palo Alto
Registry updated 2026-02-09
NCT07222735
Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas
Trial Treatment · Phase 1 · St. Jude Children's Research Hospital
St. Jude Children's Research Hospital, Memphis
Registry updated 2026-02-09
NCT06387485
A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning
Trial Treatment · Ricoh USA, Inc.
The Ohio State University -Wexner Medical Center, Columbus · Kaiser Permanente Oakland Medical Center, Oakland · William Beaumont University Hospital, Royal Oak
Registry updated 2026-02-06
NCT03465592
Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma
Trial Treatment · Phase 1/2 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Johns Hopkins Hospital, Baltimore · Johns Hopkins All Children's Hospital, St. Petersburg · Albert Einstein College of Medicine, Children's Hospital at Montefiore, The Bronx · New York Medical Center/ Maria Fareri Children's Hospital, Valhalla
Registry updated 2026-02-05
NCT04872543
A Study of ASTX727 in People With Malignant Peripheral Nerve Sheath Tumors (MPNST)
Trial Treatment · Phase 2 · Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge · Memorial Sloan Kettering Commack (Limited protocol activities), Commack · Memorial Sloan Kettering Westchester (Limited Protocol Activities), Harrison · Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown · Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale · Memorial Sloan-Kettering Cancer Center, New York · Memorial Sloan Kettering Nassau (Limited Protocol Activities), Uniondale
Registry updated 2026-02-05
NCT07125183
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
Trial Treatment · Phase 2 · University of Colorado, Denver
University of Colorado Hospital, Aurora
Registry updated 2026-02-05
NCT06500065
68Ga-DOTATATE PET/CT for the Diagnosis of Soft Tissue Sarcomas
Trial Treatment · Ohio State University Comprehensive Cancer Center
Ohio State University Comprehensive Cancer Center, Columbus
Registry updated 2026-02-02
NCT04389281
X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma
Trial Treatment · Phase 1 · Immunolight, LLC
Levine Cancer Institute, Charlotte · Duke University, Durham · Prisma Health, Greenville · Sibley Hospital - Johns Hopkins University, Washington D.C.
Registry updated 2026-01-30
NCT04390737
Evaluate the Safety and Clinical Activity of HH2853
Trial Treatment · Phase 1/2 · Haihe Biopharma Co., Ltd.
Mayo Clinic, Jacksonville · Mayo Clinic, Phoenix · Mayo Clinic, Rochester · NEXT Oncology, San Antonio
Registry updated 2026-01-30
NCT05542407
ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer
Trial Treatment · Phase 1 · UNC Lineberger Comprehensive Cancer Center
Lineberger Comprehensive Cancer Center, Chapel Hill
Registry updated 2026-01-29
NCT05634369
A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue
Trial Treatment · Phase 1/2 · Nationwide Children's Hospital
Roswell Park Comprehensive Cancer Center, Buffalo · University of North Carolina, Chapel Hill · Levine Cancer Institute, Charlotte · Cleveland Clinic, Cleveland · Nationwide Children's Hospital, Columbus · UT Southwestern, Dallas · Duke Children's Hospital/Duke Health, Durham · University of Florida, Gainesville · University of Texas - MD Anderson Cancer Center, Houston · Nemours Jacksonville, Jacksonville · Arkansas Children's Hospital, Little Rock · Children's Hospital of Los Angeles, Los Angeles · University of Miami, Miami · Vanderbilt University Medical Center, Nashville · Stanford University, Palo Alto · Children's Hospital of Philadelphia, Philadelphia · Phoenix Children s Hospital, Phoenix · Primary Children's Hospital, Salt Lake City · University of Alabama, South Birmingham · Washington University/St Louis Childrens, St Louis · Johns Hopkins All Children's Hospital, St. Petersburg · Montefiore Medical Center, The Bronx
Registry updated 2026-01-28
NCT06371768
Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
Trial Treatment · Duke University
Duke Cancer Institute, Durham
Registry updated 2026-01-28
NCT04995003
HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma
Trial Treatment · Phase 1 · Baylor College of Medicine
Texas Children's Hospital, Houston
Registry updated 2026-01-22
NCT04690374
Registry to Collect Health Information About Desmoplastic Small Round Cell Tumor
Research · Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Registry updated 2026-01-12
NCT06946225
ACTengine® IMA203 Combined With mRNA-4203
Trial Treatment · Phase 1 · Immatics US, Inc.
Dana-Farber Cancer Institute, Boston · MD Anderson Cancer Center, Houston · Memorial Sloan-Kettering Cancer Center, New York · University of California San Francisco, San Francisco
Registry updated 2026-01-08
NCT05400603
Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma
Trial Treatment · Phase 1 · Emory University
Children's Healthcare of Atlanta, Atlanta
Registry updated 2025-12-26
NCT03422198
Short Course Vaginal Cuff Brachytherapy in Treating Participants With Stage I-II Endometrial Cancer
Trial Treatment · Phase 3 · University of Utah
MD Anderson, Houston · Loyola University Medical Center, Maywood · Stanford Cancer Center, Palo Alto · Huntsman Cancer Institute/University of Utah, Salt Lake City · Intermountain Medical Center / LDS Hospital, Salt Lake City
Registry updated 2025-12-12
NCT06943521
A Study of MT-4561 in Patients With Various Advanced Solid Tumors
Trial Treatment · Phase 1/2 · Tanabe Pharma America, Inc.
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center, Columbus · START | Midwest, Grand Rapids · The University of Texas MD Anderson Cancer Center, Houston · University of Southern California, Los Angeles
Registry updated 2025-12-11

All Sarcoma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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