Sarcoma: open trials in United States

301 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT04308330
Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies
Trial Treatment · Phase 1 · New York Medical College
New York Medical College, Valhalla
Registry updated 2026-04-15
NCT04693377
Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial
Trial Treatment · M.D. Anderson Cancer Center
M D Anderson Cancer Center, Houston
Registry updated 2026-04-15
NCT07402577
Brief Title Mechanisms of Cancer-Related Pain and Opioid Use Among Adolescents and Young Adult Sarcoma Survivors: Pilot Feasibility Study
Research · Roswell Park Cancer Institute
Roswell Park Comprehensive Cancer Center, Buffalo
Registry updated 2026-04-15
NCT07436364
Application of Contrast-enhanced Ultrasound in Monitoring Soft Tissue Sarcoma Response to Neoadjuvant Radiotherapy
Trial Treatment · Early phase 1 · Thomas Jefferson University
Thomas Jefferson University Hospital, Philadelphia
Registry updated 2026-04-14
NCT04921917
Exercise and Soft Tissue Sarcoma
Trial Treatment · Duke University
Duke University, Durham
Registry updated 2026-04-08
NCT06445166
Propranolol for the Treatment of Kaposi Sarcoma in Adults
Trial Treatment · Phase 2 · Washington University School of Medicine
Washington University School of Medicine, St Louis
Registry updated 2026-04-06
NCT05868629
Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors
Research · Novartis Pharmaceuticals
Oncology Hematology Care, Inc, Cincinnati · Rocky Mountain Cancer Centers, Denver · Duke Clinical Research Institute, Durham · El Paso Texas Oncology, El Paso · Sarah Cannon Research Institute, Nashville · Texas Oncology - San Antonio, San Antonio · Lundquist Inst BioMed at Harbor, Torrance · Johns Hopkins University, Washington D.C.
Registry updated 2026-04-01
NCT07007273
Pembrolizumab for Advanced Cutaneous Sarcomas Not Including Angiosarcoma
Trial Treatment · Phase 2 · H. Lee Moffitt Cancer Center and Research Institute
Ohio State University Comprehensive Cancer Center, Columbus · MD Anderson Cancer Center, Houston · Moffitt Cancer Center, Tampa
Registry updated 2026-04-01
NCT05743426
Disease Outcomes and Toxicities in Patients With Gastrointestinal and Sarcomatous Malignancies
Research · UNC Lineberger Comprehensive Cancer Center
University of North Carolina at Chapel Hill, Department of Radiation Oncology, Chapel Hill
Registry updated 2026-03-30
NCT06905132
Preoperative 5-Day Radiotherapy for Soft Tissue Sarcoma
Trial Treatment · Phase 2 · Medical University of South Carolina
Medical University of South Carolina, Charleston
Registry updated 2026-03-30
NCT03721068
Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma
Trial Treatment · Phase 1 · UNC Lineberger Comprehensive Cancer Center
Emory Winship Cancer Institute, Atlanta · Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill
Registry updated 2026-03-27
NCT06751355
Precision Imaging to Evaluate Kaposi Sarcoma (PRIME-KS): A Device Feasibility Trial
Research · Washington University School of Medicine
Washington University School of Medicine, St Louis
Registry updated 2026-03-25
NCT07487870
Radiographic Evaluation of Tumor Biology During Neoadjuvant Radiotherapy for Sarcoma
Trial Treatment · Andrew Frankart
University of Cincinnati Medical Center, Cincinnati
Registry updated 2026-03-23
NCT07048249
Single Arm Romiplostim to Prevent CIT
Trial Treatment · Early phase 1 · Children's Hospital Medical Center, Cincinnati
Cincinnati Children's Hospital Medical Center, Cincinnati · Phoenix Children's, Phoenix
Registry updated 2026-03-18
NCT07477457
A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma
Trial Treatment · Phase 2 · Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities), Basking Ridge · Memorial Sloan Kettering at Suffolk-Commack (Limited Protocol Activities), Commack · Memorial Sloan Kettering at Westchester (Limited Protocol Activities), Harrison · Memorial Sloan Kettering at Monmouth (Limited Protocol Activities), Middletown · Memorial Sloan Kettering at Bergen (Limited Protocol Activities), Montvale · Memorial Sloan Kettering Cancer Center (All Protocol Activites), New York · Memorial Sloan Kettering at Nassau (Limited Protocol Activities), Uniondale
Registry updated 2026-03-17
NCT06384404
Upfront Surgical Resection for Osteosarcoma
Research · Montefiore Medical Center
Montefiore Medical Center, The Bronx
Registry updated 2026-03-16
NCT01804634
Reduced Intensity Haploidentical BMT for High Risk Solid Tumors
Trial Treatment · Phase 2 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore · Albert Einstein College of Medicine, Children's Hospital at Montefiore, The Bronx · New York Medical Center/ Maria Fareri Children's Hospital, Valhalla
Registry updated 2026-03-13
NCT05033288
Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone
Research · Mayo Clinic
Mayo Clinic in Florida, Jacksonville · Mayo Clinic in Rochester, Rochester · Mayo Clinic in Arizona, Scottsdale
Registry updated 2026-03-13
NCT05735184
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
Trial Treatment · Phase 1 · Kura Oncology, Inc.
University Of Michigan Comprehensive Cancer Center, Ann Arbor · Emory Healthcare - The Emory Clinic, Atlanta · Georgia Cancer Center at Augusta University, Augusta · University of Colorado, Aurora · Sarah Cannon Research Institute - St. David's South Austin Medical Center / Texas Oncology South Austin, Austin · Johns Hopkins School of Medicine, Baltimore · Massachusetts General Hospital, Boston · Roswell Park Comprehensive Cancer Center, Buffalo · Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago · Cleveland Clinic Taussig Cancer Institute, Cleveland · University Hospitals Cleveland Medical Center*, Cleveland · The James Cancer Hospital and Solove Research Institute, Columbus · UT Southwestern Simmons Cancer Center, Dallas · Colorado Blood Cancer Institute, Denver · Karmanos Cancer Institute, Detroit · Duke Blood Cancer Center, Durham · The University of Kansas Medical Center Research Institute, Fairway · Hackensack University Medical Center, Hackensack · MD Anderson Cancer Center, Houston · University of Iowa Hospitals & Clinics, Iowa City · Mayo Clinic- Jacksonville, Jacksonville · Ochsner MD Anderson Cancer Center, Jefferson · Moores UC San Diego Cancer Center, La Jolla · USC / Norris Comprehensive Cancer Center, Los Angeles · UCLA - Bowyer Oncology Center, Los Angeles · University of Kentucky Markey Cancer Center, Louisville · Norton Cancer Institute St. Matthews, Louisville · University of Wisconsin Hospital and Clinics, Madison · Loyola University Medical Center, Maywood · Medical College of Wisconsin Cancer Center, Milwaukee · University of Minnesota, Minneapolis · TriStar Bone Marrow Transplant, Nashville · Rutgers Cancer Institute, New Brunswick · Yale Cancer Center and Smilow Cancer Hospital, New Haven · Mount Sinai - Ruttenberg Treatment Center, New York · New York - Presbyterian / Weill Cornell Medicine, New York · Columbia University Medical Center, New York · OU Health Stephenson Cancer Center, Oklahoma City · UC Irvine Health- Chao Family Comprehensive Cancer Center, Orange · Hospital of the University of Pennsylvania, Philadelphia · Mayo Clinic Phoenix, Phoenix · Mayo Clinic - Rochester, Rochester · Stony Brook University Hospital, Stony Brook · UMass Chan Medical School, Worcester
Registry updated 2026-03-13
NCT05755113
A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma
Trial Treatment · Phase 2 · QBiotics Group Limited
Memorial Sloan Kettering Cancer Centre, New York
Registry updated 2026-03-12
NCT06349642
Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform
Research · Mayo Clinic
Mayo Clinic in Florida, Jacksonville · Mayo Clinic in Arizona, Phoenix · Mayo Clinic in Rochester, Rochester
Registry updated 2026-03-12
NCT02701153
Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort
Trial Treatment · Jonsson Comprehensive Cancer Center
UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
Registry updated 2026-03-10
NCT03141021
Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors
Research · Washington University School of Medicine
Johns Hopkins, Baltimore · National Institutes of Health (NIH), Bethesda · Dana-Farber Cancer Institute, Boston · University of Minnesota, Minneapolis · Memorial Sloan-Kettering Cancer Center, New York · Lifespan, Providence · University of Utah, Salt Lake City · Washington University School of Medicine, St Louis · Moffitt Cancer Center, Tampa
Registry updated 2026-03-09
NCT05672108
Phase II Trial of Lung Chemoemobolization
Trial Treatment · Phase 2 · City of Hope Medical Center
City of Hope Medical Center, Duarte · Memorial Sloan-Kettering Cancer Center, New York
Registry updated 2026-03-05
NCT07447050
Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
Trial Treatment · Phase 2 · University of California, Irvine
Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange
Registry updated 2026-03-03

All Sarcoma trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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