Sjögren's disease: open trials in Italy

10 open trials have a site in Italy. Registry data; only the trial team decides who can take part.

NCT07737743
A Phase 2a/b Study to Assess the Efficacy, Safety and Tolerability of DDY391 in Participants With Sjögren's Disease
Trial Treatment · Phase 2 · Novartis Pharmaceuticals
Fondazione Policlinico Universitario Campus Bio-medico In Forma A Bbreviata Fon, Rome · Humanitas Mirasole S.p.A., Rozzano · Azienda Sanitaria Universitaria Friuli Centrale, Udine
Registry updated 2026-10-28
NCT07404865
Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease
Trial Treatment · Phase 3 · Vor Biopharma
Azienda Ospedaliero-Universitaria delle Marche, Ancona · Ospedale San Raffaele S.r.l., Milan · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Università Campus Bio-Medico di Roma, Rome · Humanitas Mirasole S.p.A., Rozzano
Registry updated 2026-10-19
2026-526767-38-00
A randomized, parallel-group, open-label, Phase IIb pilot trial to evaluate the effectiveness in reducing systemic disease activity with methotrexate compared with hydroxychloroquine in adult male and female participants with moderate-to-severe primary Sjögren’s disease (MOSAIC STUDY)
Trial Treatment · Phase 2 · Fondazione Policlinico Universitario Campus Bio-medico In Forma A Bbreviata Fon
Azienda Sanitaria Locale di Pescara, Pescara · Fondazione Policlinico Universitario Campus Bio-medico In Forma A Bbreviata Fon, Rome · Azienda Ospedaliera Ordine Mauriziano di Torino, Turin
Registry updated 2026-10-15
NCT07621809
Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom Burden
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Azienda Ospedaliera Santa Croce E Carle, Cuneo · Azienda Ospedaliero Universitaria Pisana, Pisa · Azienda Ospedaliera Policlinico Universitario Tor Vergata, Rome · Humanitas Mirasole S.p.A., Rozzano · Azienda Sanitaria Universitaria Friuli Centrale, Udine
Registry updated 2026-10-13
NCT07041099
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease
Trial Treatment · Phase 1 · Cullinan Therapeutics Inc.
Fondazione Policlinico Universitario A. Gemelli, Roma
Registry updated 2026-08-11
NCT06991114
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Trial Treatment · Phase 2 · Artiva Biotherapeutics, Inc.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia · Ospedale San Raffaele S.r.l., Milan · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-07-31
NCT07371468
A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD)
Trial Treatment · Phase 1 · GlaxoSmithKline
University Hospital Of Ferrara, Ferrara · Humanitas Mirasole S.p.A., Rozzano
Registry updated 2026-06-23
2025-521462-96-00
A Phase 1b, Open-Label Study of CLN-978 for the Treatment of Active, Moderate to Severe Sjogren’s Disease
Trial Treatment · Phase 1 · Cullinan Therapeutics Inc.
Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
Registry updated 2026-05-06
NCT06747949
A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)
Trial Treatment · Phase 3 · Amgen
Azienda Ospedaliero-Universitaria Policlinico G. Rodolico-San Marco Di Catania, Catania · Azienda Ospedaliero-Universitaria Careggi, Florence · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · Azienda Ospedaliero Universitaria Pisana, Pisa · Azienda USL IRCCS di Reggio Emilia, Reggio Emilia · Fondazione Policlinico Universitario Campus Bio-medico In Forma A Bbreviata Fon, Rome · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino, Turin · Azienda Sanitaria Universitaria Friuli Centrale, Udine · Centro Ricerche Cliniche di Verona s.r.l., Verona
Registry updated 2026-04-28
NCT06338735
Ultra-High Frequency Ultrasonography in Sjögren's Syndrome
Trial Treatment · University of Pisa
University of Pisa, Pisa
Registry updated 2024-06-26

All Sjögren's disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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