Systemic sclerosis (scleroderma): open trials in Germany

9 open trials have a site in Germany. Registry data; only the trial team decides who can take part.

NCT06925542
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
Trial Treatment · Phase 1 · CRISPR Therapeutics
University of Augsburg, Augsburg · Universitätsklinikum Köln, Cologne · Medizinische Hochschule Hannover (MHH), Hanover · UCT University Medical Center Mainz, Mainz
Registry updated 2026-10-26
NCT07873931
A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases
Trial Treatment · Phase 1 · Bristol-Myers Squibb
Local Institution - 0028, Berlin · Local Institution - 0060, Erlangen · Local Institution - 0059, Magdeburg · Local Institution - 0027, Würzburg
Registry updated 2026-10-14
2025-523061-22-00
A Phase II, Open-Label, Single-Center, Single-Arm Pilot Study to Evaluate the Safety, Tolerability and Efficacy of Blinatumomab for Treatment of Patients with Autoimmune B-Cell driven Diseases including Systemic Lupus Erythematosus (SLE), Systemic Sclerosis (SSc) and Granulomatous Polyangiitis (GPA), BlinA-B trial
Trial Treatment · Phase 2 · Universitaet Leipzig
Universitaet Leipzig, Leipzig
Registry updated 2026-10-02
NCT05878717
A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease
Trial Treatment · Phase 2/3 · GlaxoSmithKline
Krankenhaus Porz am Rhein gGmbH, Cologne · Universitaetsklinikum Duesseldorf AöR, Duesseldorf · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Muhlenkreiskliniken AöR, Minden · Universitaetsklinikum Tuebingen AöR, Tuebingen
Registry updated 2026-09-08
NCT06195072
Platform Clinical Study for Conquering Scleroderma
Trial Treatment · Phase 2 · Scleroderma Research Foundation, Inc.
Universitaetsklinikum Duesseldorf AöR, Duesseldorf · Universitaetsklinikum Erlangen AöR, Erlangen · Universitaetsklinikum Schleswig-Holstein AöR, Luebeck · Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöR, Mainz · Marienhaus Klinikum Mainz GmbH, Mainz · Klinikum der Universitaet Muenchen AöR, Munich
Registry updated 2026-08-18
NCT06991114
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Trial Treatment · Phase 2 · Artiva Biotherapeutics, Inc.
Artiva Investigational Site Bonn, Bonn · Artiva Investigational Site Munchen, München
Registry updated 2026-07-31
NCT07115745
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Trial Treatment · Phase 1 · Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Charite Universitaetsmedizin Berlin KöR, Berlin · Technische Universitaet Dresden, Dresden · Universitaetsklinikum Duesseldorf AöR, Duesseldorf · University Medical Center Hamburg-Eppendorf, Hamburg · Universitaetsklinikum Schleswig-Holstein AöR, Kiel
Registry updated 2026-07-14
2025-524435-39-00
A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of 250 mg lebrikizumab in patients with localized scleroderma (LEMO)
Trial Treatment · Phase 2 · Charite Universitaetsmedizin Berlin KöR
Charite Universitaetsmedizin Berlin KöR, Berlin · Universitaetsklinikum Carl Gustav Carus Dresden an der Technischen Universitaet Dresden AöR, Dresden · Universitaetsklinikum Erlangen AöR, Erlangen · Medical Center- University of Freiburg, Freiburg im Breisgau · HELIOS St. Elisabeth Klinik Oberhausen GmbH, Oberhausen · Eberhard Karls Universitaet Tuebingen, Tuebingen
Registry updated 2026-07-03
NCT07348263
EFESO: Study on Juvenile Onset Eosinophilic Fasciitis
Research · Meyer Children's Hospital IRCCS
Hamburger Zentrum für Kinder- und Jugendrheumatologie -, Hamburg
Registry updated 2026-03-11

All Systemic sclerosis (scleroderma) trials and the map

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