Thalassaemia: open trials in Italy

10 open trials have a site in Italy. Registry data; only the trial team decides who can take part.

NCT07506863
A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)
Trial Treatment · Phase 3 · Agios Pharmaceuticals, Inc.
ARNAS G. Brotzu, Cagliari · Azienda Ospedaliera di Padova, Padova
Registry updated 2026-10-29
NCT07517133
A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With α- or β-Non-Transfusion-Dependent Thalassemia
Trial Treatment · Phase 3 · Agios Pharmaceuticals, Inc.
ARNAS G. Brotzu, Cagliari
Registry updated 2026-10-28
NCT06609226
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
Trial Treatment · Phase 3 · Novo Nordisk A/S
Azienda Ospedaliero-Universitaria San Luigi Gonzaga, Orbassano · Azienda Ospedaliera di Padova, Padova · Fondazione IRCCS Policlinico San Matteo, Pavia
Registry updated 2026-09-18
NCT04208529
A Long-term Follow-up Study in Participants Who Received CTX001
Trial Treatment · Phase 3 · Vertex Pharmaceuticals Incorporated
Bambino Gesu Childrens Hospital, Rome
Registry updated 2026-08-11
NCT07680803
Gene-Modified Stem Cell Therapy for Subjects With Transfusion-dependent Beta-thalassemia
Trial Treatment · Phase 2 · Fondazione Telethon
San Raffaele Hospital, Milan · Ospedale Pediatrico Bambino Gesù, Rome
Registry updated 2026-07-27
NCT04143724
Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia
Trial Treatment · Phase 2 · Celgene
Galliera Hospital, Genoa · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Azienda Ospedaliero-Universitaria San Luigi Gonzaga, Orbassano · Ospedale Pediatrico Bambino Gesù, Rome
Registry updated 2026-07-10
NCT04064060
A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials
Trial Treatment · Phase 3 · Celgene
Allessandria · Bologna · Brindisi · Cagliari · Ferrara · Florence · Florence · Ente Ospedaliero Ospedali Galliera - Centro della Microcitemia e delle Anemie Congenite, Genoa · Lecce · Maggiore Polyclinic Hospital, IRCCS Ca' Granda, Milan · Modena · AOU dell'Università degli Studi della Campania Luigi Vanvitelli, Naples · AORN A. Cardarelli, Naples · Azienda Ospedaliero-Universitaria S.Luigi Gonzaga, Orbassano · Pavia · Reggio Calabria · Roma · Rozzano · Varese · Verona
Registry updated 2026-07-01
NCT05477563
Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease
Trial Treatment · Phase 3 · Vertex Pharmaceuticals Incorporated
Ospedale Pediatrico Bambino Gesù, Rome
Registry updated 2026-03-23
NCT05508932
Atrial Fibrillation in Beta-Thalassemia
Research · University Hospital of Ferrara
Matteo Bertini, Ferrara
Registry updated 2026-02-24
NCT05693909
A Trial Testing SP-420 in Subjects With Transfusion-dependent β-thalassemia or Low-risk Myelodysplastic Syndromes
Trial Treatment · Phase 2 · Pharmacosmos A/S
Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico, Bologna · ARNAS G. Brotzu, Cagliari · Azienda Ospedaliero-Universitaria Careggi, Florence · Ente Ospedaliero Ospedali Galliera Di Genova, Genoa · IRCCS Ospedale Policlinico San Martino, Genoa · ASST Grande Ospedale Metropolitano Niguarda, Milan · Ospedale San Raffaele S.r.l., Milan · Azienda Ospedaliero - Universitaria di Modena, Modena · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples · Fondazione IRCCS Policlinico San Matteo, Pavia
Registry updated 2025-09-24

All Thalassaemia trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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