Thyroid cancer: open trials in United States

76 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT01005654
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
Research · National Cancer Institute (NCI)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-05
NCT01109420
Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer
Research · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-05
NCT01247597
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study
Research · National Cancer Institute (NCI)
National Institutes of Health Clinical Center, Bethesda · National Cancer Institute - Shady Grove, Rockville
Registry updated 2026-11-05
NCT03160274
Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions
Research · The University of Texas Health Science Center at San Antonio
University of Texas Health Science Center, San Antonio
Registry updated 2026-11-05
NCT04927416
The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer
Trial Treatment · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-05
NCT05229341
Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules
Trial Treatment · City of Hope Medical Center
City of Hope Medical Center, Duarte
Registry updated 2026-11-05
NCT06959511
Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery
Trial Treatment · Phase 2 · M.D. Anderson Cancer Center
University of Michigan, Ann Arbor · Massachusetts General Hospital, Boston · University of Virginia, Charlottesville · Cleveland Clinic Taussig Cancer Institute, Cleveland · MD Anderson Cancer Center, Houston
Registry updated 2026-11-05
NCT06991738
177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer
Trial Treatment · Phase 1/2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-11-05
NCT02609685
Active Surveillance of Papillary Thyroid Microcarcinoma
Trial Treatment · Cedars-Sinai Medical Center
Cedars-Sinai Medical Center, Los Angeles
Registry updated 2026-11-04
NCT05366881
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
Research · Adela, Inc
Elligo Health Research, Inc., Austin · Medical University of South Carolina, Charleston · Cleveland Clinic, Cleveland · Baptist Corbin, Corbin · City of Hope, Duarte · Baptist Hardin, Elizabethtown · McLeod Health, Florence · North Georgia Health System, Gainesville · Baptist Lexington, Lexington · Baptist (BHMCC), Memphis · Miami Cancer Institute, Miami · Allina Health Cancer Institute, Minneapolis · Vanderbilt-Ingram Cancer Center, Nashville · Baptist Floyd, New Albany · Baptist Paducah, Paducah · Oregon Health Sciences University, Portland · Mayo Clinic, Rochester
Registry updated 2026-11-04
NCT05999630
Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer
Trial Treatment · Phase 3 · Vanderbilt University Medical Center
Vanderbilt University Medical Center, Nashville
Registry updated 2026-11-03
NCT00001160
Studies on Tumors of the Thyroid
Research · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-10-29
NCT03841617
The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
Trial Treatment · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health Clinical Center, Bethesda
Registry updated 2026-10-29
NCT07620574
Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study
Trial Treatment · Phase 3 · Exelixis
New York Cancer and Blood Specialists, Bay Shore · The University of Texas MD Anderson Cancer Center, Houston · Greater Dayton Cancer Center, Kettering · The West Clinic, Memphis
Registry updated 2026-10-28
NCT03382158
International PPB/DICER1 Registry
Research · Children's Hospitals and Clinics of Minnesota
Children's Minnesota, Minneapolis
Registry updated 2026-10-26
NCT05783323
Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer
Trial Treatment · Phase 2 · Children's Hospital of Philadelphia
Dana-Farber Cancer Institute, Boston · MD Anderson Cancer Center, Houston · St. Jude Children's Research Hospital, Memphis · Children's Hospital of Philadelphia, Philadelphia · University of California San Francisco, San Francisco · Seattle Children's Hospital, Seattle
Registry updated 2026-10-21
NCT07886905
Pulsed Stereotactic Ablative Radiotherapy (PULSAR) With Systematic Therapy for Thyroid Cancer
Trial Treatment · Phase 2 · Washington University School of Medicine
Washington University School of Medicine, St Louis
Registry updated 2026-10-21
NCT07612293
STAGE-MTC Trial Thyroid Lobectomy With Ipsilateral Central Neck Dissection
Trial Treatment · Jonsson Comprehensive Cancer Center
UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
Registry updated 2026-10-19
NCT06007924
A Study of Avutometinib and Defactinib in People With Thyroid Cancer
Trial Treatment · Phase 2 · Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge · Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Limited Protocol Activities), Commack · Memorial Sloan Kettering Westchester (Limited Protocol Activities), Harrison · Memorial Sloan Kettering Monmouth (Limited Protocol Activities), Middletown · Memorial Sloan Kettering Bergen (Limited Protocol Activities), Montvale · Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York · Memorial Sloan Kettering Nassau (Limited Protocol Activities), Rockville Centre
Registry updated 2026-10-15
NCT06239194
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
Trial Treatment · Phase 1/2 · ModeX Therapeutics, An OPKO Health Company
Massachusetts General Hospital, Boston · Sarah Cannon Research Institute, Denver · MD Anderson Cancer Center, Houston · Sylvester Comprehensive Cancer Center - University of Miami Health System, Miami · Sarah Cannon Research Institute, Nashville · NEXT Oncology, San Antonio
Registry updated 2026-10-15
NCT07529080
Personalized Cancer Support (Thrive Track) to Manage the Emotional Needs of Young Adults With Thyroid, Melanoma and Testicular Cancer, PerCS-YA Trial
Trial Treatment · University of Michigan Rogel Cancer Center
University of Michigan Rogel Cancer Center, Ann Arbor
Registry updated 2026-10-15
NCT07470489
Zanzalintinib Plus Cemiplimab for the Treatment of BRAF Wild-Type Anaplastic Thyroid Cancer
Trial Treatment · Phase 2 · M.D. Anderson Cancer Center
MD Anderson Cancer Center, Houston
Registry updated 2026-10-14
NCT05786924
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Trial Treatment · Phase 1/2 · Institut de Recherches Internationales Servier
University of Colorado - Aurora Cancer Center, Aurora · Dana-Farber Cancer Institute, Boston · Cleveland Clinic, Cleveland · Duke University School of Medicine, Durham · NEXT Virginia, Fairfax · Banner Health- MD Anderson Cancer Center, Gilbert · South Texas Accelerated Research Therapeutics (START) Midwest, Grand Rapids · MD Anderson Cancer Center, Houston · USC / Norris Comprehensive Cancer Center, Los Angeles · The Angeles clinic - A cedars SINAI AFFILIATE, Los Angeles · Masonic Cancer Center, University of Minnesota, Minneapolis · Sarah Canon Research Institute (SCRI) Oncology Partners, Nashville · Yale University School of Medicine - Yale Cancer Center, New Haven · NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York · Memorial Sloan-Kettering Cancer Center, New York · START | San Antonio, San Antonio · University of California, San Francisco (UCSF), San Francisco · Fred Hutchinson Cancer Research Center, Seattle · Washington University, St Louis · Sibley Memorial Hospital, Washington D.C. · Georgetown University Lombardi Cancer Center, Washington D.C.
Registry updated 2026-10-13
NCT07661420
211At-MABG in Adults With Advanced Neuroendocrine Cancers
Trial Treatment · Phase 1 · University of Pennsylvania
University of Pennsylvania/Abramson Cancer Center, Philadelphia
Registry updated 2026-10-07
NCT07863765
Enfortumab Vedotin for the Treatment of Unresectable or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer, Anaplastic Thyroid Cancer, Medullary Thyroid Cancer, or NUT Carcinoma
Trial Treatment · Phase 2 · Northwestern University
Northwestern University, Chicago
Registry updated 2026-10-07

All Thyroid cancer trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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