Thyroid cancer trials in United States

In United States 76 Also abroad 226

76 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Not yet taking people in United States
Enfortumab Vedotin for the Treatment of Unresectable or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer, Anaplastic Thyroid Cancer, Medullary Thyroid Cancer, or NUT Carcinoma
Where
Chicago
Age
18 years and over
People
56
Run by
Northwestern University
See details and how to joinNCT07863765
Phase 1/2Taking people
Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors
Where
Gilbert, Seattle, Tucson
Age
18 years to 99 years
People
30
Run by
University of Arizona
See details and how to joinNCT06814496
Phase 1Taking people
XL092 and Cemiplimab in BRAF WT Thyroid Cancer
Where
Boston, Chapel Hill
Age
18 years and over
People
12
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT06902376
No phaseTaking people
Natural History of Medullary Thyroid Cancer to Inform Advanced Disease Management
Where
Houston, San Francisco
Age
18 years and over
People
2,030
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT04216732
No phaseTaking people
DESTINY-PANTUMOUR04
Where
Birmingham, Boulder, Bullhead City, Canton, Casa Grande, Coral Springs, Dallas, Decatur, Durham, Farmington, Maumee, Nashville, Philadelphia, San Diego, St. Petersburg, Topeka, West Palm Beach, Wilson
Age
18 years to 130 years
People
100
Run by
AstraZeneca
See details and how to joinNCT07124000
No phaseTaking people
Cultural Adaptation of an Educational Tool in Medullary Thyroid Cancer
Where
Houston
Age
18 years and over
People
40
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT07142005
Phase 3Taking people
Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer
Where
Aberdeen, Allentown, Alma, Alpena, Alton, Anaconda, Anchorage, Ankeny, Ann Arbor, Atlanta, Aurora, Baker City, Ballwin, Baltimore, Barrington, Bellingham, Bemidji, Bend, Bethlehem, Bettendorf, Billings, Bismarck, Boise, Bolivar, Bozeman, Branson, Brighton, Burbank, Burlington, Burnsville, Caldwell, Cambridge, Canton, Cape Girardeau, Caro, Carroll, Cary, Cedar Rapids, Centralia, Chapel Hill, Charleston, Chaska, Chelsea, Cheyenne, Chicago, City of Saint Peters, Clackamas, Clarkston, Clive, Cody, Coeur d'Alene, Coon Rapids, Coos Bay, Council Bluffs, Creston, Creve Coeur, Crown Point, Crystal Lake, Cudahy, DeKalb, Derby, Des Moines, Detroit, Downers Grove, Durham, East China, East Stroudsburg, Eau Claire, Edina, Edmonds, Elgin, Emmett, Erie, Everett, Fairbanks, Fairfield, Fargo, Flint, Fort Dodge, Fort Lauderdale, Fort Smith, Franklin, Fruitland, Garden City, Geneva, Germantown, Gladwin, Glastonbury, Glenview, Grafton, Grand Rapids, Grayslake, Great Bend, Great Falls, Green Bay, Greenwich, Grosse Pointe Woods, Guilford, Hartford, Havre, Hazel Crest, Hazleton, Helena, Highlands Ranch, Hood River, Iowa City, Irvine, Issaquah, Jacksonville, Joplin, Kalispell, Kennewick, Kenosha, Lacey, Lake Forest, Lansing, Lawton, Lexington, Libertyville, Little Rock, Livonia, Longview, Macomb, Maple Grove, Maplewood, Marinette, Marlette, Marshfield, Meridian, Midland, Milwaukee, Minneapolis, Minocqua, Missoula, Monticello, Mount Pleasant, Mount Vernon, Muskegon, Nampa, Napa, Nashville, Newberg, New Haven, New Lenox, New Richmond, New Ulm, North Haven, Norton Shores, Oak Lawn, Oklahoma City, Omaha, Ontario, Orange, Oregon City, Orland Park, Osage Beach, Oshkosh, Palo Alto, Palos Heights, Park Ridge, Pella, Philadelphia, Pittsburg, Pittsburgh, Pontiac, Portland, Post Falls, Princeton, Racine, Raleigh, Redmond, Rice Lake, Robbinsdale, Rochester, Rolla, Saginaw, Saint Joseph, Saint Louis Park, Saint Paul, Salt Lake City, Sandpoint, Santa Rosa, Seattle, Sedro-Woolley, Shakopee, Sheboygan, Sheridan, Shiloh, Sioux Falls, Spokane, Springfield, Stamford, Stevens Point, Stillwater, St Louis, Summit, Tawas City, Thief River Falls, Torrington, Trumbull, Twin Falls, Two Rivers, Vancouver, Waconia, Walla Walla, Warren, Warrenville, Washington, Waterbury, Waterford, Waukee, Wauwatosa, West Allis, West Branch, West Des Moines, Westerly, Weston, Willmar, Woodbury, Worthington, Wyoming, Ypsilanti
Age
18 years and over
People
264
Run by
ECOG-ACRIN Cancer Research Group
See details and how to joinNCT06475989
Phase 1Taking people
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors
Where
Boston, Iowa City, Royal Oak, Seattle
Age
18 years to 100 years
People
116 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07006727 · EU 2024-519111-34-00
No phaseTaking people
Global Real World Data in Patients With Advanced Thyroid Cancer on Standard of Care and Specialized Interventions- Registry of Oncologic Outcomes With Testing and Treatment.
Where
Houston
Age
18 years and over
People
459
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT06507878
No phaseTaking people
Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers
Where
Houston
Age
18 years and over
People
50
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT07140757
Phase 1Taking people
Lesion Dosimetry With Iodine-124 in Metastatic Thyroid Carcinoma
Where
New York
Age
18 years and over
People
75
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT03647358
No phaseEnrolling by invitation
Database Linkage Study to Evaluate the Risk of Medullary Thyroid Carcinoma
Where
Parsippany
Age
18 years and over
People
93,600,000
Run by
Novo Nordisk A/S
See details and how to joinNCT07713901
No phaseTaking people
A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer
Where
New York
Age
18 years and over
People
300 worldwide
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07225309
Phase 2Taking people
Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer
Where
Ann Arbor
Age
18 years and over
People
22
Run by
University of Michigan Rogel Cancer Center
See details and how to joinNCT03099356
Phase 2Taking people
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
Where
Baltimore, Beverly Hills, Boston, Colombus, Columbus, Dallas, Duluth, Houston, Maumee, Miami, Morgantown, Nashville, New York, Norwalk, Omaha, Philadelphia, Providence, Rockville, Saint Joseph, San Francisco, Seattle, Summit, Temple, Toledo, Westwood, Los Angeles, Winston-Salem
Age
8 years and over
People
254 worldwide
Run by
Fore Biotherapeutics
See details and how to joinNCT05503797 · EU 2024-513578-23-00
Phase 2Taking people
Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)
Where
Houston, Memphis, Philadelphia, San Francisco, Seattle
Age
2 years to 25 years
People
13
Run by
Children's Hospital of Philadelphia
See details and how to joinNCT06458036
No phaseTaking people
Patient Decision Aid in Supporting Decision-Making About When to Start or Stop New Drugs, Join Clinical Trials, or Continue Active Surveillance in Patients With Medullary Thyroid Cancer and Their Caregivers
Where
Houston
Age
18 years and over
People
120
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT03892993
Phase 1Taking people
Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases
Where
Houston
Age
12 years to 50 years
People
44
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT03093909
No phaseTaking people
Health and Wellness Coaching to Improve Adherence to Healthy Habits and Treatment Plans in Papillary and Follicular Thyroid Cancer Survivors
Where
Jacksonville
Age
18 years and over
People
20
Run by
Mayo Clinic
See details and how to joinNCT07545837
No phaseTaking people
Navigation Intervention for Adolescent and Young Adult Cancer Survivors
Where
Pasadena
Age
21 years to 45 years
People
25
Run by
Kaiser Permanente
See details and how to joinNCT07406087
Phase 1Taking people
Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer
Where
Baltimore
Age
18 years to 85 years
People
48
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT04892303
No phaseTaking people
Integrated Cancer Repository for Cancer Research
Where
Aitkin, Alliance, Aurora, Bozeman, Brainerd, Canton, Council Bluffs, Daytona Beach, DeLand, Duluth, Fargo, Fayetteville, Fergus Falls, Fort Wayne, Glens Falls, Green Bay, Greenwood Village, Hastings, Holyoke, Kansas City, Liberty, Manchester, Minot, Norfolk, North Kansas City, North Platte, Omaha, Orange City, Overland Park, Palm Coast, Randallstown, Saint Joseph, Tallahassee, Utica, Waterloo, Westminster, Yorkville
Age
19 years to 110 years
People
999,999
Run by
University of Nebraska
See details and how to joinNCT02012699
Phase 2Taking people
XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer
Where
Chicago, Torrance
Age
18 years and over
People
33
Run by
Jochen Lorch
See details and how to joinNCT06959641
Phase 2Taking people
Comparison of I-124 PET/CT for the Diagnosis of Thyroid Cancer
Where
San Francisco
Age
13 years and over
People
62
Run by
Thomas Hope
See details and how to joinNCT06961084
No phaseTaking people
Environmental Factors and Thyroid Cancer
Where
New York
Age
18 years and over
People
500
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT05172921