Type 1 diabetes: open trials in United Kingdom

33 open trials have a site in United Kingdom. Registry data; only the trial team decides who can take part.

NCT07222137
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
Trial Treatment · Phase 3 · Eli Lilly and Company
Queen Elizabeth Hospital Birmingham, Birmingham · Birmingham Children's Hospital, Birmingham · Addenbrooke's Hospital, Cambridge · University Hospital of Wales, Cardiff · Noah's Ark Children's Hospital for Wales, Cardiff · Queen Elizabeth University Hospital, Glasgow · Royal London Hospital, London · St. George's Hospital, London · The John Radcliffe Hospital, Oxford · Southampton General Hospital, Southampton
Registry updated 2026-11-04
NCT07222332
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
Trial Treatment · Phase 3 · Eli Lilly and Company
Aberdeen Royal Infirmary, Aberdeen · Birmingham Children's Hospital, Birmingham · Queen Elizabeth Hospital Birmingham, Birmingham · Southmead Hospital, Bristol · Addenbrooke's Hospital, Cambridge · University Hospital of Wales, Cardiff · Churchill Hospital, Oxford · Southampton General Hospital, Southampton
Registry updated 2026-11-04
NCT06325202
Closed Loop and Education for Hypoglycemia Awareness Restoration
Trial Treatment · Milton S. Hershey Medical Center
University of Leicester, Leicester · University of Sheffield, Sheffield
Registry updated 2026-10-30
NCT07088068
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
Trial Treatment · Phase 3 · Sanofi
Bath · Cambridge · Dundee · Glasgow · Guildford · Leeds · London · London · London · Reading · Sheffield
Registry updated 2026-10-13
NCT07187531
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
Trial Treatment · Phase 2 · SAb Biotherapeutics, Inc.
Cambridge University Hospitals NHS Foundation Trust - Addenbrookes Hospital, Cambridge · Noahs Ark Childrens Hospital for Wales, Cardiff · NHS Lothian, Royal Hospital for Sick Children, Edinburgh · Alder Hey Children's NHS Foundation Trust, Liverpool · Barts Health NHS Trust , The Royal London Hospital, London · University College London Hospitals NHS Foundation Trust - University College Hospital, London · Nottingham University Hospitals NHS Trust - Queen's Medical Centre (QMC), Nottingham · Oxford University Hospitals NHS Trust, John Radcliffe Hospital, Oxford
Registry updated 2026-10-13
NCT07776509
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
Trial Treatment · Phase 3 · AstraZeneca
Airdrie · Chippenham · Hull · Llandough · Rotherham
Registry updated 2026-09-25
NCT05663515
A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs
Research · AstraZeneca
Edinburgh · London
Registry updated 2026-09-24
NCT07828626
Benefits of Retained Insulin for Good Health
Research · Royal Devon and Exeter NHS Foundation Trust
D1 Wolfson Centre Research and Development, Bath · Clinical Research Centre, Bristol · NIHR Exeter Clinical Research Facility, Exeter · Diabetes and Endocrine Centre, Truro
Registry updated 2026-09-18
NCT04786262
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Trial Treatment · Phase 3 · Vertex Pharmaceuticals Incorporated
Royal Infirmary of Edinburgh, Edinburgh · Churchill Hospital, Headington · Cardiovascular, Metabolic Medicine and Sciences, King's College London, London · The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne
Registry updated 2026-09-01
NCT07797335
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
Trial Treatment · Phase 3 · Novo Nordisk A/S
Southmead Hospital, Bristol · University Hospital Coventry - WISDEM Centre, Coventry · Hull Royal Infirmary - Diabetes, Hull · Ipswich Hospital - Diabetes, Ipswich · Altnagelvin Area Hospital, Londonderry · North Coast Medical Ltd, Newquay · Clifton Medical Centre, Rotherham · Joint Clinical Research Facility - Swansea, Swansea · Egremont Medical Centre, Wallasey · Yeovil Hospital, Yeovil
Registry updated 2026-09-01
NCT07457580
Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs)
Research · Sanofi
Birmingham · London
Registry updated 2026-08-26
NCT07769138
Implementation of Networked Continuous Glucose Monitoring With Telemetry Within the Intensive Care Unit (ICU-TeleCGM)
Research · Imperial College Healthcare NHS Trust
Imperial College Healthcare NHS Trust, London
Registry updated 2026-08-17
NCT07583238
Diathermy On Diabetes Glucose Monitoring Effectiveness
Research · University of Nottingham
Queen'S Medical Centre, Nottingham
Registry updated 2026-05-13
NCT07065383
Rebalancing the Fat Content of the Heart and Muscles
Trial Treatment · University of Aberdeen
Cardiac Research Office, Aberdeen Royal Infirmary, Aberdeen
Registry updated 2026-04-30
NCT07401901
Evaluation of the Safety and Effectiveness of the Novel Medtronic Experimental Automated Insulin Delivery System (NMX8) in Adults Living With Type 1 Diabetes
Trial Treatment · Medtronic MiniMed, Inc.
Cambridge University Hospitals NHS Foundation Trust - Addenbrooke's Hospital, Cambridge · Leicester General Hospital, Leicester · Manchester University NHS Foundation Trust - Manchester Royal Infirmary, Manchester
Registry updated 2026-04-28
NCT06815081
Capillary OGTT Study
Research · University of Oxford
Noah's Ark Childrens Hospital for Wales, Cardiff · Royal London Barts Health NHS Trust, London · Nottingham Childrens Hospital, Nottingham · John Radcliffe Hospital, Oxford
Registry updated 2026-04-13
NCT06435156
Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes
Trial Treatment · Phase 2 · University of Dundee
Aberdeen Royal Infirmary, Aberdeen · Addenbrookes Hospital, Cambridge · Ninewells Hospital, Dundee · Royal Infirmary of Edinburgh, Edinburgh · Glasgow Royal Infirmary, Glasgow Clinical Research Facility, Glasgow · Leicester General Hospital, Leicester · Aintree University Hospital, Liverpool · Prince Philip Hospital, Llanelli · St. George's University Hospitals NHS Foundation Trust, London · Guy's Hospital, London · Manchester Royal Infirmary Hospital, Manchester · Wythenshawe Hospital, Manchester · North Manchester General Hospital, Manchester · Northern General Hospital, Sheffield · Moorgreen Hospital, Southampton · Kings Mill Hospital, Sutton in Ashfield
Registry updated 2026-04-06
NCT05754567
CONCEPTT Kids International Neurodevelopmental Outcomes Among Offspring of Women With Type 1 Diabetes
Research · University of Manitoba
NHS Lothian Royal Infirmary of Edinburgh, Edinburgh · Glasgow Royal Infirmary, Glasgow · Ipswich Hospital NHS Trust, Ipswich · St. James's Hospital, Leeds Teaching Hospitals Trust NHS Trust, Leeds · Southampton General Hospital, Southampton
Registry updated 2026-03-20
NCT07051005
Feasibility of a Tailored Online Self-compassion Intervention
Trial Treatment · Canterbury Christ Church University
Betsi Cadwaladr University Health Board (BCUHB), Bangor · Barts Health NHS Trust, London
Registry updated 2026-03-20
NCT06782568
Avoidance of Insulin-induced Lipohypertophy in People With Diabetes Using Ultrasound Scanning Within Diabetes Clinics
Trial Treatment · Imperial College London
Imperial College Healthcare NHS Trust, London
Registry updated 2026-02-13
NCT07341243
Exercising in Hot Conditions: How Does it Effect Blood Glucose in People With T1D
Trial Treatment · Liverpool John Moores University
Liverpool John Moores University, Liverpool
Registry updated 2026-01-14
NCT07251257
The Seafarers' Continuous Glucose Monitoring Systems Study
Research · University of Surrey
University of Surrey FHMS Nutritional Sciences, Guildford
Registry updated 2026-01-06
NCT03369821
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study)
Research · University of Exeter
Royal Devon & Exeter NHS Foundation Trust, Exeter · King's College London, London
Registry updated 2025-12-19
NCT07193446
Optimising the Delivery of Diabetes Distress Informed Care for Its Prevention, Detection, and Management in Adults With Type 1 Diabetes: a Feasibility Study (D-stress Study)
Trial Treatment · Guy's and St Thomas' NHS Foundation Trust
Royal United Hospitals Bath, Bath · University Hospitals Leicester NHS Trust, Leicester · Guy's and St Thomas' Hospitals NHS Trust, London
Registry updated 2025-12-04
NCT06452654
Anti-viral Action Against Type 1 Diabetes Autoimmunity
Trial Treatment · Phase 4 · Technical University of Munich
Birmingham Women's and Children's NHS Foundation Trust, Birmingham · Cambridge University Hospitals NHS Foundation Trust, Cambridge · The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle
Registry updated 2025-09-23

All Type 1 diabetes trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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