Type 1 diabetes trials in United States

In United States 216 Also abroad 539

216 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseNot yet taking people in United States
Food is Medicine in Pediatric Patients With Diabetes
Where
Worcester
Age
5 years to 17 years
People
50
Run by
University of Massachusetts, Worcester
See details and how to joinNCT07535502
No phaseTaking people
ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Where
Baltimore
Age
8 years to 21 years
People
500
Run by
Johns Hopkins University
See details and how to joinNCT05463289
No phaseTaking people
App-Based Certified Diabetes Education Therapy (AB-CDE)
Where
Aurora, Boston, Indianapolis, Los Angeles, New York, Portland
Age
18 years and over
People
99
Run by
Oregon Health and Science University
See details and how to joinNCT07282639
Phase 1Taking people
A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity
Where
Miami
Age
18 years to 70 years
People
18
Run by
Eli Lilly and Company
See details and how to joinNCT07803744
No phaseTaking people
Type 1 Diabetes Extension Study
Where
Atlanta, Aurora, Boston, Indianapolis, Iowa City, Kansas City, Minneapolis, New Haven, San Francisco, Seattle, Sioux Falls, Stanford
Age
8 years to 35 years
People
111
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT02734277
Phase 2Taking people
METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)
Where
Seattle
Age
18 years to 69 years
People
60 worldwide
Run by
University of Washington
See details and how to joinNCT07699380
Phase 1/2Taking people
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
Where
Ann Arbor, Atlanta, Aurora, Austin, Baltimore, Bloomfield Township, Boston, Buffalo, Chattanooga, Chicago, Cleveland, Dallas, Durham, Fort Myers, Gainesville, Greenville, Hialeah, Humble, Idaho Falls, Indianapolis, Jacksonville, Kansas City, Memphis, Miami, Minneapolis, Newport Beach, New York, Raleigh, San Antonio, San Diego, Seattle, Smithfield, Springfield, St Louis, Tampa, Tucson, Walnut Creek, Waxahachie
Age
12 years to 35 years
People
72
Run by
COUR Pharmaceutical Development Company, Inc.
See details and how to joinNCT06783309
Phase 2Taking people
Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG
Where
Aurora, Gainesville, New Haven, New York, Pittsburgh, Seattle
Age
4 years to 34 years
People
60
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT07216391
No phaseTaking people
Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes
Where
Durham, Providence
Age
16 years to 50 years
People
235
Run by
Duke University
See details and how to joinNCT05540704
No phaseTaking people
The iLet Experience Study
Where
Irvine
Age
6 years and over
People
1,875
Run by
Beta Bionics, Inc.
See details and how to joinNCT06891898
Phase 2Taking people
Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus
Where
Aurora, Boston, Gainesville, Indianapolis, Miami, Minneapolis, Nashville, New Haven, New York, Pittsburgh, Salt Lake City, San Francisco, Seattle, Tampa
Age
8 years to 45 years
People
66 worldwide
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT07142252
No phaseNot yet taking people in United States
Single Arm Intervention Trial of DEKA TWIIST TM Insulin Pump Utilizing Tidepool Loop Algorithm in Pregnant People With Pre-existing Type 1 Diabetes
Where
Aurora, New York, Rochester, Stanford
Age
18 years to 45 years
People
32
Run by
Mayo Clinic
See details and how to joinNCT07808385
Phase 3Taking people
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Where
Baltimore, Boston, Chicago, Dallas, Duarte, Madison, Miami, Philadelphia, Pittsburgh, Richmond, San Francisco
Age
18 years to 65 years
People
57 worldwide
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT04786262 · EU 2024-513929-23-00
No phaseTaking people
Remedy to Diabetes Distress (R2D2): A Scalable Screen to Treat Program for School-age Families
Where
Jacksonville, Kansas City
Age
8 years to 65 years
People
180
Run by
Nemours Children's Clinic
See details and how to joinNCT05268250
Phase 3Taking people
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
Where
Albany, Amarillo, Austin, Baltimore, Beaver, Birmingham, Boston, Bountiful, Bristol, Cincinnati, Clearwater, Conroe, Cordele, Corpus Christi, Council Bluffs, Covington, Crystal River, Dallas, Delray Beach, Detroit, Fairhope, Flint, Fort Mill, Fort Worth, Franklin, Greenfield, Gurnee, Hazel Crest, Hollywood, Houston, Idaho Falls, Iowa City, Jacksonville, Kansas City, Katy, Knoxville, Lakeland, Lancaster, Las Vegas, Layton, Lexington, Lincoln, Lomita, Longview, Los Alamitos, Los Angeles, Lufkin, Manassas, Manlius, Maumee, Mesquite, Miami, Miami Lakes, Miramar, Montgomery, Morehead City, Mt. Pleasant, Muncie, Myrtle Beach, Nashville, Newport, New Port Richey, New Windsor, New York, Norman, Northridge, Oak Brook, Ocala, Omaha, Palm Harbor, Pembroke Pines, Peoria, Richmond, Saint Augustine, Salem, Salt Lake City, San Antonio, San Diego, San Dimas, Scottsdale, Spring Valley, Statesville, St Louis, Sugar Land, The Bronx, Topeka, Troy, Tucker, Weslaco, West Des Moines, West Seneca, Winchester, Winston-Salem, Ypsilanti
Age
45 years and over
People
1,778 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07797335
No phaseTaking people
HLA Demographics Study in Adults With Type 1 Diabetes
Where
Boston, Chapel Hill, Gainesville, New York, San Francisco
Age
18 years to 55 years
People
200
Run by
GentiBio, Inc
See details and how to joinNCT06860516
No phaseTaking people
Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes
Where
Albany, Austin, Baltimore, Detroit, Morehead City, Sandy City
Age
18 years to 80 years
People
102
Run by
DreaMed Diabetes
See details and how to joinNCT07599982
No phaseTaking people
Family Intervention for Black Teens With Type 1 Diabetes
Where
Detroit, Memphis, Washington D.C.
Age
10 years to 14 years
People
216
Run by
Wayne State University
See details and how to joinNCT06275412
No phaseTaking people
Pilot Implementation Trial of Implementation Toolkits for Diabetes Coaching
Where
Wilmington
People
15
Run by
Nemours Children's Clinic
See details and how to joinNCT07766811
Phase 2Taking people
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
Where
Indianapolis
Age
11 years to 18 years
People
114
Run by
Heba M. Ismail
See details and how to joinNCT05414409
Phase 1/2Taking people
A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus
Where
Chicago
Age
35 years to 70 years
People
13
Run by
Otsuka Pharmaceutical Factory, Inc.
See details and how to joinNCT06575426
No phaseTaking people
APP-MNT: App-Enhanced Medical Nutrition Therapy on Glycemic Outcomes and Quality of Life
Where
New York
Age
18 years to 75 years
People
52
Run by
Weill Medical College of Cornell University
See details and how to joinNCT07773779
No phaseEnrolling by invitation
Personalized Comprehensive Diabetes Support for Children With Newly Diagnosed Type 1 Diabetes
Where
Sacramento
Age
0 years to 16 years
People
60
Run by
University of California, Davis
See details and how to joinNCT06057662
No phaseTaking people
Diabetes Multimorbidity Typology, Trajectory, and Feasibility of an Audio Diary Mobile Application to Support Self-management
Where
Atlanta
Age
65 years and over
People
30
Run by
Emory University
See details and how to joinNCT07474376
No phaseTaking people
NOURISH - A Healthcare-community Partnership to Improve Nutrition for Optimal Glycemic Control and Pregnancy Outcomes With Pregestational Diabetes
Where
Columbus
Age
18 years and over
People
174
Run by
Ohio State University
See details and how to joinNCT07560813