Type 2 diabetes: open trials in South Africa

7 open trials have a site in South Africa. Registry data; only the trial team decides who can take part.

NCT07662109
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
Trial Treatment · Phase 3 · AstraZeneca
Brackenfell · Cape Town · Claremont · Durban · eMkhomazi · Johannesburg · KwaDukuza · Paarl · Pretoria
Registry updated 2026-10-30
NCT07064473
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Trial Treatment · Phase 3 · Boehringer Ingelheim
Lakeview Hospital, Benoni · IATROS International, Bloemfontein · Tread Research, Cape Town · Langeberg Clinical Trials, Cape Town · Paarl Research Centre, Cape Town · Johese Clinical Research: Midstream, Centurion · Canal Walk Clinical Trial Centre, Century City · Synapta Clinical Research Centre, Durban · Prof N Ranjith Cardiovascular Research Centre, Durban · Clinresco Centre, Gauteng · Lenasia Clinical Trial Centre, Johannesburg · Life The Glynnwood, Johannesburg · Diabetes Care Centre, Johannesburg · Dr Garda Cardiology Practice, Johannesburg · Drs H & V Makan, Johannesburg · Meditrial, Pietermaritzburg · Clinical Trial Systems (Pty) Ltd, Pretoria · Jongaie Research, Pretoria · Dr I.O Ebrahim Inc, Pretoria · Diabetes Care Centre, Pretoria · Global Clinical Trials, Raslouw · Helderberg Research Institute, Somerset West · Vergelegen Medi-Clinic, Somerset West · Wits Clinical Research Chris Hani Baragwanath Hospital, Soweto · Tiervlei Trial Centre, Tygervalley · Clinical Projects Research, Worcester · CareKahle Pty Ltd, Wynberg
Registry updated 2026-10-28
NCT07667803
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Trial Treatment · Phase 3 · AstraZeneca
Bellville · Bloemfontein · Cape Town · Chatsworth · Claremont · Durban · eMkhomazi · Johannesburg · Midrand · Wentworth
Registry updated 2026-10-13
NCT07613307
A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting
Trial Treatment · Phase 3 · Eli Lilly and Company
JOSHA Research, Bloemfontein · Tiervlei Trial Centre, Cape Town · Synopsis Research, Cape Town · Tread Research, Cape Town · TASK Central, Cape Town · Synergy Biomed Research Institute (SBRI), East London · Aliwal Shoal Medical Centre, eMkhomazi · Fola Health, Johannesburg · Trident Clinical, Kimberley · Ubuntu Clinical Research Krugersdorp, Krugersdorp · Drs H & V Makan Centre for Diabetes, Lenasia · Be Part Research (PTY) LTD, Paarl · Emmed Research, Pretoria · Dr JM Engelbrecht Trial Site, Somerset West
Registry updated 2026-10-08
NCT07564414
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Trial Treatment · Phase 3 · Novo Nordisk A/S
IATROS International, Bloemfontein · Medi-Clinic Bloemfontein, Bloemfontein · Tread Research (Pty)Ltd, Cape Town · Dr Pillay's Rooms, Durban · Soweto Clinical Trial Centre, Johannesburg · Johannesburg · Hemant Makan, Johannesburg · Sandton Medical Research, Johannesburg · Newtown Clinical Research, Johannesburg · Lenasia Clinical Trial Centre, Lenasia · Dr Hendrik Snyman's Practice, Mossel Bay · Paarl Research Centre, Paarl, Cape Town · Phoenix Pharma, Port Elizabeth · Clinical Trial Systems (CTC), Pretoria · Clinical Trials Network Helderberg (Pty) Ltd, Somerset West
Registry updated 2026-09-30
NCT03549754
iCaReMe Global Registry: Multinational Real-world Evidence in Cardiorenal and Metabolic Diseases
Research · AstraZeneca
Florida · Parow · Umhlanga
Registry updated 2026-09-09
NCT07662044
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus
Trial Treatment · Phase 3 · AstraZeneca
Brackenfell · Cape Town · Claremont · Durban · eMkhomazi · Johannesburg · KwaDukuza · Paarl · Pretoria
Registry updated 2026-08-31

All Type 2 diabetes trials and the map

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Type 2 diabetes: open trials in South Africa

A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting

A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

iCaReMe Global Registry: Multinational Real-world Evidence in Cardiorenal and Metabolic Diseases

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus