Ulcerative colitis: open trials in France

50 open trials have a site in France. Registry data; only the trial team decides who can take part.

2023-507853-13-00
An Adaptive, Dose-Ranging, Phase 2 Study of Eltrekibart Given Alone or in Combination with Mirikizumab for the Treatment of Adult Patients with Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 2 · Eli Lilly & Co.
Assistance Publique Hopitaux De Paris, Creteil Cedex · Centre Hospitalier Universitaire Grenoble Alpes, Grenoble Cedex 9 · Centre Hospitalier Departemental Vendee, La Roche Sur Yon Cedex 9 · Centre Hospitalier Universitaire de Nice, Nice · Hospices Civils de Lyon, Pierre-Bénite · Centre Hospitalier Universitaire Rouen, Rouen Cedex
Registry updated 2026-11-05
NCT06937086
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Trial Treatment · Phase 3 · Eli Lilly and Company
Clinique des Cèdres, Échirolles · CHD Vendée, La Roche-sur-Yon · Hôpitaux Universitaires Paris Sud - Hôpital Bicêtre, Le Kremlin-Bicêtre · CHU Saint-Eloi, Montpellier · Centres Médico Chirurgicaux - Clinique Ambroise Paré, Neuilly-sur-Seine · Centre Hospitalier Universitaire de Nice - Hôpital l'Archet, Nice · Hôpital Saint-Antoine, Paris · Centre Hospitalier Universitaire de Saint Etienne - Hopital Nord, Saint-Priest-en-Jarez · CHU Rangueil, Toulouse
Registry updated 2026-11-04
NCT07415044
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 2 · Eli Lilly and Company
Centres Médico Chirurgicaux - Clinique Ambroise Paré, Neuilly-sur-Seine · CHU Bordeaux Haut-Leveque, Pessac · Centre Hospitalier Lyon-Sud, Pierre-Bénite · CHU Rangueil, Toulouse
Registry updated 2026-11-04
NCT06651281
Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Centre Hospitalier Universitaire De Lille, Lille Cedex · Centre Medico Chirurgical Ambroise Pare Hartmann, Neuilly-Sur-Seine · Centre Hospitalier Universitaire de Nice, Nice · CHRU De Nancy, Vandoeuvre Les Nancy
Registry updated 2026-11-03
NCT06663332
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Centre Hospitalier Universitaire De Lille, Lille Cedex
Registry updated 2026-11-03
NCT07577856
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Centre Hospitalier Universitaire Amiens Picardie, Amiens Cedex 1 · CHU Besancon, Besancon Cedex · Assistance Publique Hopitaux De Paris, Clichy · Assistance Publique Hopitaux De Paris, Creteil · Assistance Publique Hopitaux De Paris, Le Kremlin-Bicetre · Centre Hospitalier Universitaire de Lille, Lille · Centre Hospitalier Universitaire De Montpellier, Montpellier Cedex 5 · CHRU De Nancy, Nancy Cedex · Centre Hospitalier Universitaire de Nantes, Nantes · Centre Medico Chirurgical Ambroise Pare Hartmann, Neuilly-Sur-Seine · Centre Hospitalier Universitaire de Nice, Nice · Centre Hospitalier Universitaire de Bordeaux, Pessac · Hospices Civils de Lyon, Pierre-Bénite · Centre Hospitalier Universitaire Reims, Reims Cedex · Centre Hospitalier Universitaire de Saint Etienne, Saint-Priest-en-Jarez · Centre Hospitalier Universitaire De Toulouse, Toulouse Cedex 9
Registry updated 2026-11-03
NCT07652294
Long-term Safety and Efficacy of Multiple Long-acting Antibodies Alone and in Combinations for IBD
Trial Treatment · Phase 2 · Spyre Therapeutics, Inc.
Centre Hospitalier Regional De Marseille, Marseille · Clinique Jules Verne, Nantes · Centre Hospitalier Universitaire de Nice, Nice · Hospices Civils de Lyon, Pierre-Bénite · Centre Hospitalier Universitaire de Saint Etienne, Saint-Priest-en-Jarez
Registry updated 2026-11-03
NCT06979336
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Trial Treatment · Phase 2 · Genentech, Inc.
University Hospital Of Clermont-Ferrand, Clermont-Ferrand · Centre Medico Chirurgical Ambroise Pare Hartmann, Neuilly-Sur-Seine · Hospices Civils de Lyon, Pierre-Bénite · Centre Hospitalier Universitaire de Saint Etienne, Saint-Priest-en-Jarez
Registry updated 2026-10-27
NCT07012395
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Trial Treatment · Phase 2 · Spyre Therapeutics, Inc.
Centre Hospitalier Regional De Marseille, Marseille · Clinique Jules Verne, Nantes · Centre Hospitalier Universitaire de Nice, Nice · Hospices Civils de Lyon, Pierre-Bénite · Centre Hospitalier Universitaire de Saint Etienne, Saint-Priest-en-Jarez
Registry updated 2026-10-27
2024-511458-32-00
A study evaluating the effects of filgotinib in children and teenagers with ulcerative colitis
Trial Treatment · Phase 3 · Alfasigma S.p.A.
Hospital Femme Mere Enfant, Bron · Centre Hospitalier Universitaire de Dijon, Dijon · Groupement Des Hopitaux De L'Institut Catholique De Lille, Lille Cedex · CHU de Montpellier, Montpellier Cedex 05 · Centre Hospitalier Universitaire de Rennes, Rennes · Centre Hospitalier Régional Universitaire de Tours, Tours
Registry updated 2026-10-26
NCT07470879
A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis
Trial Treatment · Phase 2 · Pfizer
Hospices Civils de Lyon, Bron · Hopital Necker Enfants Malades, Paris · Robert Debre University Hospital, Paris
Registry updated 2026-10-26
NCT07184996
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Sanofi
Lille · Nice · Vandœuvre-lès-Nancy
Registry updated 2026-10-23
NCT07463183
A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Clinique des Cèdres, Échirolles · Chorale Du Centre Hospitalier De Lens, Lens · Clinique Jules Verne, Nantes
Registry updated 2026-10-23
2025-524404-29-00
A study of LY4268989 in participants with Moderately to Severely Active Ulcerative Colitis (EMERALD-3)
Trial Treatment · Phase 2 · Eli Lilly & Co.
Centre Medico Chirurgical Ambroise Pare Hartmann, Neuilly-Sur-Seine · Centre Hospitalier Universitaire de Bordeaux, Pessac · Hospices Civils de Lyon, Pierre-Bénite · Centre Hospitalier Universitaire De Toulouse, Toulouse Cedex 9
Registry updated 2026-10-21
NCT07576452
FirST Lines of Biologics in pAtients With ulceRaTivE Colitis: a Randomised Controlled Trial
Trial Treatment · Phase 4 · University Hospital, Clermont-Ferrand
Centre Hospitalier Universitaire Amiens - Picardie, Amiens · Centre Hospitalier d'Avignon, Avignon · Centre Hospitalier de la Cote Basque, Bayonne · CHU Besançon, Besançon · Centre Hospitalier Regional Universitaire De Tours, Chambray Les Tours · University Hospital Of Clermont-Ferrand, Clermont Ferrand Cedex 1 · Hopital Beaujon, Clichy · Centre Hospitalier De Colmar, Colmar Cedex · Centre Hospitalier Intercommunal Créteil, Créteil · Assistance Publique Hopitaux De Paris, Creteil Cedex · Centre Hospitalier Universitaire Grenoble Alpes, Grenoble Cedex 9 · Centre Hospitalier Departemental Vendee, La Roche Sur Yon Cedex 9 · Bicetre Hospital, Le Kremlin Bicetre Cedex · Centre Hospitalier Universitaire de Lille, Lille · Centre Hospitalier Et Universitaire de Limoges, Limoges · Hospital La Croix Rousse Hcl, Lyon Cedex 04 · Centre Hospitalier Regional De Marseille, Marseille · Centre Hospitalier Universitaire De Montpellier, Montpellier Cedex 5 · Centre Hospitalier Universitaire de Nantes, Nantes · Centre Hospitalier Universitaire de Nice, Nice · Centre Hospitalier Universitaire De Nimes, Nimes Cedex 9 · Assistance Publique Hopitaux de Paris, Paris · Institut Mutualiste Montsouris, Paris · Hopital Saint Antoine, Paris Cedex 12 · Assistance Publique Hopitaux De Paris, Paris Cedex 18 · Centre Hospitalier Universitaire De Bordeaux, Pessac Cedex · Centre Hospitalier Universitaire de Poitiers, Poitiers · Centre Hospitalier Universitaire De Rennes, Rennes Cedex 9 · Groupe Hospitalier Rance Emeraude, Saint-Malo Cedex · Centre Hospitalier Universitaire de Saint Etienne, Saint-Priest-en-Jarez · Centre Hospitalier Intercommunal Toulon / La Seine-Sur-Mer, Toulon · Centre Hospitalier Universitaire De Toulouse, Toulouse Cedex 9 · Centre Hospitalier Valence, Valence · CHRU De Nancy, Vandoeuvre Les Nancy
Registry updated 2026-10-21
NCT07845487
A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 2 · Palisade Bio
Site FR-003, Amiens · Site FR-005, Clermont-Ferrand · Site FR-002, Neuilly-sur-Seine · Site FR-001, Nice · Site FR-004, Saint-Priest-en-Jarez
Registry updated 2026-10-21
NCT05076175
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb
Bron · Centre Hospitalier Universitaire de Caen - Hôpital Côte de Nacre, Caen · Paris · Paris · CHU de Toulouse - Hôpital des Enfants, Toulouse
Registry updated 2026-10-20
NCT06865417
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Trial Treatment · Phase 3 · Alfasigma S.p.A.
Hospital Femme Mere Enfant, Bron · Centre Hospitalier Universitaire de Dijon, Dijon · Hopital Saint Vincent de Paul - GHICL Lille, Lille · CHU de Montpellier, Montpellier · Centre Hospitalier Universitaire de Rennes, Rennes · Centre Hospitalier Régional Universitaire de Tours, Tours
Registry updated 2026-10-20
NCT07185009
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Sanofi
Amiens · Besançon · Créteil · La Tronche · Lille · Marseille · Nantes · Nice · Paris · Saint-Priest-en-Jarez · Toulouse · Vandœuvre-lès-Nancy
Registry updated 2026-10-16
NCT06805890
Study of Tissue Repair in Inflammatory Bowel Disease Exploiting Organoid Technology
Trial Treatment · Assistance Publique Hopitaux De Marseille
Nord Hospital, Marseille
Registry updated 2026-09-21
NCT07804511
Adapted Physical Activity for Persistent Fatigue in Patients With Inflammatory Bowel Disease in Remission
Trial Treatment · University Hospital, Grenoble
CHU Grenoble Alpes, Grenoble
Registry updated 2026-09-11
2023-509248-86-00
A phase 2/3, multicenter, randomized, double-blind study to evaluate the efficacy, safety, pharmacokinetics and pharmacodynamics of oral ozanimod (RPC1063) in pediatric subjects with moderately to severely active ulcerative colitis with an inadequate response to conventional therapy.
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb Services Unlimited Company
Hospital Femme Mere Enfant, Bron · Centre Hospitalier Universitaire De Caen Normandie, Caen Cedex 9 · Hopital Necker Enfants Malades, Paris · Hopital Des Enfants, Toulouse Cedex 9
Registry updated 2026-07-22
NCT07718529
Safety and Efficacy of a STOPping Strategy Versus Classical Maintenance Dose of JAK Inhibitors in Deep Remission Patients With Ulcerative Colitis
Trial Treatment · Phase 4 · Assistance Publique Hopitaux De Marseille
Centre Hospitalier Universitaire Amiens Picardie, Amiens Cedex 1 · Centre Hospitalier d'Avignon, Avignon · CHU Besançon, Besançon · University Hospital Of Clermont-Ferrand, Clermont-Ferrand · Hopital Beaujon, Clichy · Assistance Publique Hopitaux De Paris, Creteil · Bicetre Hospital, Le Kremlin Bicetre Cedex · Centre Hospitalier Universitaire De Lille, Lille Cedex · Centre Hospitalier Regional De Marseille, Marseille · Centre Hospitalier Universitaire De Montpellier, Montpellier Cedex 5 · Centre Hospitalier Universitaire de Nantes, Nantes · Centre Medico Chirurgical Ambroise Pare Hartmann, Neuilly-Sur-Seine · Centre Hospitalier Universitaire de Nice, Nice · Centre Hospitalier Universitaire De Nimes, Nimes Cedex 9 · Centre Hospitalier Universitaire De Bordeaux, Pessac Cedex · Hospices Civils de Lyon, Pierre-Bénite · Centre Hospitalier Universitaire De Rennes, Rennes Cedex 9 · Centre Hospitalier Universitaire Rouen, Rouen Cedex · Centre Hospitalier Universitaire de Saint Etienne, Saint-Etienne · Centre Hospitalier Intercommunal Toulon / La Seine-Sur-Mer, Toulon · Centre Hospitalier Universitaire De Toulouse, Toulouse Cedex 9 · CHRU De Nancy, Vandoeuvre Les Nancy
Registry updated 2026-07-22
NCT07529236
Digestive Evolution of Children With Crohn's Disease or Ulcerative Colitis Whose Anti-TNFα Treatment Was Switched to Ustekinumab Due to Paradoxical Psoriasis,
Trial Treatment · Centre Hospitalier Universitaire de Nice
CHU de Nice, Nice
Registry updated 2026-06-25
NCT06228352
Role of Bile Acids and Microbiota in Clostridioides Difficile Infection in Ulcerative Colitis
Research · Assistance Publique - Hôpitaux de Paris
Hopital Necker Enfants Malades, Paris
Registry updated 2026-06-24

All Ulcerative colitis trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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