Ulcerative colitis: open trials in United Kingdom

26 open trials have a site in United Kingdom. Registry data; only the trial team decides who can take part.

NCT07158242
A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Hoffmann-La Roche
Birmingham Children's Hospital, Birmingham · Addenbrooke's Hospital, Cambridge · Great North Children's Hospital, Newcastle upon Tyne · Sheffield Childrens Hospital, Sheffield
Registry updated 2026-11-05
NCT07747480
A Sub Study to Investigate the Safety and Tolerability of Aletekitug in Participants With Moderate To Severe Ulcerative Colitis
Trial Treatment · Phase 1 · GlaxoSmithKline
Oxford
Registry updated 2026-11-05
NCT07920367
Non-Invasive Biomarker Monitoring in UC on Biologics
Research · University Hospitals Coventry and Warwickshire NHS Trust
University Hospitals Coventry and Warwickshire NHS Trust, Coventry
Registry updated 2026-11-05
NCT06937086
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Trial Treatment · Phase 3 · Eli Lilly and Company
Southmead Hospital, Bristol · Ninewells Hospital and Medical School, Dundee · Royal Devon & Exeter Hospital, Exeter · Royal London Hospital, London
Registry updated 2026-11-04
NCT06651281
Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Whipps Cross University Hospital ( Site 3400), London · MAC Research - Merseyside ( Site 3401), Prescot
Registry updated 2026-11-03
NCT06663332
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Sheffield Children's Hospital, Sheffield · Royal Stoke University Hospital, Stoke-on-Trent · Haywood Hospital, Stoke-on-Trent
Registry updated 2026-11-03
NCT07242248
A Study to Observe Real-world Evidence of Guselkumab Treatment in Participants With Ulcerative Colitis and Crohn's Disease in the United Kingdom (UK)
Research · Janssen-Cilag Ltd.
London North West University Healthcare NHS Trust, Harrow
Registry updated 2026-11-03
NCT07577856
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Addenbrookes Hospital, Cambridge · Cardiff and Vale UHB - University Hospital of Wales, Cardiff · Russells Hall Hospital, Dudley · Ninewells Hospital, Dundee · Royal Devon & Exeter Hospital, Exeter · Fairfield General Hospital, Great Chart · Whipps Cross University Hospital, Leyton · Kings College Hospital, London · Guys' and St Thomas' NHS Trust, London · St Georges Healthcare NHS Trust, London · Royal Victoria Infirmary, Newcastle upon Tyne · Oxford University Hospitals NHS Foundation Trust, Oxford
Registry updated 2026-11-03
NCT07747467
A Study to Investigate the Safety and Tolerability of Multiple Study Interventions in Participants With Moderate to Severe Ulcerative Colitis
Trial Treatment · Phase 1 · GlaxoSmithKline
Oxford
Registry updated 2026-10-28
NCT06579443
Robotic Inflammatory Bowel Disease Development, Learning and Efficacy Study
Research · University Hospitals Coventry and Warwickshire NHS Trust
University Hospitals Coventry & Warwickshire (UHCW) NHS Trust, Coventry · London North West University Healthcare NHS Trust, Harrow · Guy's and St Thomas' NHS Foundation Trust, London · Chelsea and Westminster Hospital NHS Foundation, London · Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne · Oxford University Hospitals NHS Foundation Trust, Oxford
Registry updated 2026-10-27
NCT06979336
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Trial Treatment · Phase 2 · Genentech, Inc.
Addenbrook'es Hospital, Cambridge · Royal Liverpool University Hospital, Liverpool · Guy's Hospital, London · King's College Hospital, London · John Radcliffe Hospital, Oxford
Registry updated 2026-10-27
NCT07071519
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
Trial Treatment · Phase 3 · AbbVie
Addenbrookes Hospital /ID# 271489, Cambridge · Alder Hey Children's NHS Foundation Trust /ID# 271533, Liverpool · Sheffield Children's Hospital NHS Foundation Trust /ID# 271490, Sheffield
Registry updated 2026-10-27
NCT07470879
A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis
Trial Treatment · Phase 2 · Pfizer
Bristol Royal Hospital for Children, Bristol · Alder Hey Children's Hospital, Liverpool · Evelina London Children's Hospital, London · King's College Hospital, London · Sheffield Children's Hospital, Sheffield
Registry updated 2026-10-26
NCT07463183
A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Fairfield General Hospital ( Site 1524), Bury · Addenbrooke's Hospital ( Site 1525), Cambridge · Huddersfield Royal Infirmary ( Site 1522), Huddersfield · Guys and St Thomas NHS Foundation Trust ( Site 1523), London
Registry updated 2026-10-23
NCT05076175
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
Trial Treatment · Phase 2/3 · Bristol-Myers Squibb
Birmingham Children's Hospital, Birmingham · King's College Hospital, London · London · Barts Health NHS Trust, London
Registry updated 2026-10-20
NCT06865417
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Trial Treatment · Phase 3 · Alfasigma S.p.A.
Bristol Royal Infirmary, Bristol · Ninewells Hospital, Glasgow · Alder Hey Children's Hospital, Liverpool · Chelsea And Westminster Hospital, London · Sheffield Children's Hospital, Sheffield
Registry updated 2026-10-20
NCT07185009
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Sanofi
London
Registry updated 2026-10-16
NCT07665723
An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's Processing of Medicines That Rely on Cytochrome P450 Enzymes in Participants With Ulcerative Colitis
Trial Treatment · Phase 1 · Hoffmann-La Roche
Royal Liverpool University Hospital, Liverpool · University College London Hospitals, London · Royal Victoria Infirmary, Newcastle upon Tyne
Registry updated 2026-10-16
NCT04844606
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Trial Treatment · Phase 3 · Eli Lilly and Company
Royal London Hospital, London · The John Radcliffe Hospital, Oxford · Sheffield Children's Hospital, Sheffield
Registry updated 2026-10-07
NCT03571373
PIBD-SETQuality: the Inception Cohort and Safety Registry
Research · Erasmus Medical Center
Royal Hospital London, London
Registry updated 2026-08-11
NCT06956703
NAZA - Nottingham/Astra ZenecA Prospective IBD Cohort Study
Research · University of Nottingham
University of Nottingham, Nottingham
Registry updated 2026-07-08
NCT07691138
Stopping PPI Therapy in Inactive IBD
Trial Treatment · Phase 4 · University of Nottingham
University of Nottingham, Nottingham
Registry updated 2026-07-08
NCT05442567
A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Trial Treatment · Phase 3 · Takeda
Birmingham Women's and Children's NHS Foundation Trust, Birmingham · Noahs Ark Childrens Hospital for Wales - PIN, Cardiff · Great Ormond Street Hospital, London · Barts Health NHS Trust - PPDS, London · King's College Hospital, London · Royal Manchester Children's Hospital - PPDS - PIN, Manchester
Registry updated 2026-05-07
NCT06550310
Nutrition and Clinical Outcomes in IBD
Research · Barts & The London NHS Trust
Barts Health NHS Trust, London
Registry updated 2026-02-19
NCT07295834
Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled Trial
Trial Treatment · Phase 2 · Imperial College London
Guy's and St Thomas' NHS Foundation Trust, London · Imperial College Healthcare NHS Trust, London · King's College Hospital NHS Foundation Trust, London · St Mark's Hospital, London
Registry updated 2025-12-22

All Ulcerative colitis trials and the map

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