Ulcerative colitis: open trials in Italy

49 open trials have a site in Italy. Registry data; only the trial team decides who can take part.

NCT06937086
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Trial Treatment · Phase 3 · Eli Lilly and Company
IRCCS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant'Orsola, Bologna · Ospedale Specializzato in Gastroenterologia "Saverio de Bellis", Castellana Grotte · Ospedale San Raffaele, Milan · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · Azienda Ospedale Universita Padova, Padova · Azienda Ospedaliero Universitaria Pisana, Pisa · Ospedale Di Circolo, Rho · Fondazione Policlinico Universitario Agostino Gemelli, Roma · Humanitas, Rozzano
Registry updated 2026-11-04
NCT07186101
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Trial Treatment · Phase 2 · Eli Lilly and Company
Ospedale San Raffaele, Milan · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · ASST Grande Ospedale Metropolitano Niguarda, Milan · Fondazione Policlinico Universitario Agostino Gemelli, Roma · Humanitas, Rozzano
Registry updated 2026-11-04
NCT07415044
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 2 · Eli Lilly and Company
IRCCS Policlinico San donato, Milan · Ospedale San Raffaele, Milan · Ospedale Di Circolo, Rho · Azienda Ospedaliera San Camillo Forlanini, Rome · Fondazione Policlinico Tor Vergata, Rome · Ospedale Isola Tiberina - Gemelli Isola, Rome · Humanitas, Rozzano
Registry updated 2026-11-04
NCT07483073
A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease
Trial Treatment · Phase 2 · Eli Lilly and Company
Azienda Ospedaliera Universitaria Careggi, Florence · Ospedale San Raffaele, Milan · Fondazione IRCCS San Gerardo dei Tintori, Monza · Ospedale Sacro Cuore Don G. Calabria, Negrar · Fondazione Policlinico Universitario Agostino Gemelli, Roma · Humanitas, Rozzano
Registry updated 2026-11-04
NCT06663332
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
ASST Papa Giovanni XXIII Bergamo, Bergamo · Azienda USL di Bologna - Ospedale Maggiore, Bologna · IRCCS Ospedale Pediatrico Bambino Gesù, Roma · Casa Sollievo Della Sofferenza IRCCS, San Giovanni Rotondo · IRCCS materno infantile Burlo Garofolo, Trieste
Registry updated 2026-11-03
NCT07577856
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Ospedale San Raffaele di Milano, Milan · Fondazione IRCCS Ca Granda Ospedale Policlinico Di Milano, Milan · Ospedale Sacro Cuore Negrar-Verona, Negrar · Fondazione Policlinico Universitario A Gemelli IRCCS, Romagnano · Fatebenefratelli Isola Tiberina - Gemelli Isola, Romagnano · Azienda Ospedaliera San Camillo-Forlanini, Romagnano · Istituto Clinico Humanitas, Rozzano
Registry updated 2026-11-03
NCT07652294
Long-term Safety and Efficacy of Multiple Long-acting Antibodies Alone and in Combinations for IBD
Trial Treatment · Phase 2 · Spyre Therapeutics, Inc.
Legnano · Negrar
Registry updated 2026-11-03
2025-522362-78-00
A study to measure mirikizumab levels in breast milk of lactating participants receiving mirikizumab therapeutically for an approved indication
Trial Treatment · Phase 4 · Eli Lilly & Co.
Ospedale San Raffaele S.r.l., Milan · Azienda Socio Sanitaria Territoriale Rhodense, Rho · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Azienda Sanitaria Locale Roma 2, Rome
Registry updated 2026-10-30
NCT06979336
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Trial Treatment · Phase 2 · Genentech, Inc.
Fondazione Poliambulanza, Brescia · Ospedale San Raffaele S.r.l., Milan · IRCCS Ospedale Sacro Cuore Don Calabria, Negrar · Fondazione IRCCS Policlinico San Matteo, Pavia · Azienda Socio Sanitaria Territoriale Rhodense, Rho · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Humanitas Mirasole S.p.A., Rozzano · Policlinico San Donato S.p.A., San Donato Milanese · Azienda Ospedaliera Ordine Mauriziano di Torino, Turin
Registry updated 2026-10-27
NCT07012395
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Trial Treatment · Phase 2 · Spyre Therapeutics, Inc.
Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico, Bologna · National Institute of Gastroenterology Saverio De Bellis Research Hospital, Castellana Grotte · Azienda Socio Sanitaria Territoriale Ovest Milanese, Legnano · Ospedale San Raffaele S.r.l., Milan · IRCCS Ospedale Sacro Cuore Don Calabria, Negrar · Azienda Ospedaliera di Padova, Padova · Fondazione IRCCS Policlinico San Matteo, Pavia · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Humanitas Mirasole S.p.A., Rozzano · Policlinico San Donato S.p.A., San Donato Milanese · Azienda Ospedaliera Ordine Mauriziano di Torino, Turin · Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino, Turin
Registry updated 2026-10-27
NCT07071519
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
Trial Treatment · Phase 3 · AbbVie
Azienda Ospedaliera Universitaria Federico II Di Napoli, Naples · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Casa Sollievo della Sofferenza, San Giovanni Rotondo · Istituto Di Ricovero E Cura A Carattere Scientifico Materno Infantile Burlo Garofolo, Trieste
Registry updated 2026-10-27
2024-511458-32-00
A study evaluating the effects of filgotinib in children and teenagers with ulcerative colitis
Trial Treatment · Phase 3 · Alfasigma S.p.A.
Azienda Ospedaliero-Universitaria Ss Antonio E Biagio E Cesare Arrigo, Alexandria · Azienda Ospedaliero Universitaria Ospedali Riuniti Umberto I G M Lancisi G Salesi, Ancona · ASST Fatebenefratelli Sacco, Milan · Azienda Ospedaliera Universitaria Federico II Di Napoli, Naples · Azienda Ospedaliero-Universitaria Policlinico Umberto I, Rome · Ospedale Pediatrico Bambino Gesù, Rome · Istituto Di Ricovero E Cura A Carattere Scientifico Materno Infantile Burlo Garofolo, Trieste
Registry updated 2026-10-26
NCT06992453
Multi-omics Dissection of Gut Microbiome Engraftment During FMT
Trial Treatment · Catholic University of the Sacred Heart
Catholic University of the Sacred Heart, Rome
Registry updated 2026-10-26
NCT07470879
A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis
Trial Treatment · Phase 2 · Pfizer
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo · Azienda Ospedaliera Universitaria Meyer IRCCS, Florence · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · Azienda Ospedaliera Universitaria - Universita degli Studi della Campania Luigi Vanvitelli, Naples
Registry updated 2026-10-26
NCT07184996
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Sanofi
Legnano · Milan
Registry updated 2026-10-23
NCT07463183
A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico, Bologna · Ospedale San Raffaele S.r.l., Milan · Humanitas Mirasole S.p.A., Rozzano
Registry updated 2026-10-23
2025-524404-29-00
A study of LY4268989 in participants with Moderately to Severely Active Ulcerative Colitis (EMERALD-3)
Trial Treatment · Phase 2 · Eli Lilly & Co.
Ospedale San Raffaele S.r.l., Milan · Azienda Socio Sanitaria Territoriale Rhodense, Rho · Azienda Ospedaliera Policlinico Universitario Tor Vergata, Rome · Ospedale Isola Tiberina - Gemelli Isola, Rome · San Camillo Forlanini Hospital, Rome · Humanitas Mirasole S.p.A., Rozzano · Policlinico San Donato S.p.A., San Donato Milanese
Registry updated 2026-10-21
NCT07296315
Confirmatory Clinical Study in Active Ulcerative Colitis
Trial Treatment · Phase 2 · MRM Health NV
Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro · Azienda Socio Sanitaria Territoriale Ovest Milanese, Legnano · Ospedale San Raffaele S.r.l., Milan · Azienda Ospedaliera di Padova, Padova · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Humanitas Mirasole S.p.A., Rozzano · Policlinico San Donato S.p.A., San Donato Milanese
Registry updated 2026-10-21
NCT07845487
A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 2 · Palisade Bio
Site IT-002, Bari · Site IT-004, Bologna · Site IT-007, Matera · Site IT-009, Negrar · Site IT-001, Rome · Site IT-008, Rome · Site IT-003, Rome · Site IT-006, Rozzano · Site IT-005, San Giovanni Rotondo · Site IT-010, Turin
Registry updated 2026-10-21
NCT06865417
A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis
Trial Treatment · Phase 3 · Alfasigma S.p.A.
Azienda Ospedaliero Universitaria "SS Antonio e Biagio e Cesare Arrigo", Alessandria · Azienda Ospedaliero Universitaria dell Marche I G M Lancisi G Salesi, Ancona · ASST Fatebenefratelli Sacco, Milan · Azienda Ospedaliera Universitaria Federico II Di Napoli, Naples · Ospedale Pediatrico Bambino Gesù, Rome · Azienda Ospedaliero-Universitaria Policlinico Umberto I, Rome · IRCCS materno infantile Burlo Garofolo, Trieste
Registry updated 2026-10-20
NCT07095634
Estimation of Cardiovascular Risk in Patients With Crohn's Disease and Ulcerative Colitis (PROVACI)
Research · IRCCS Policlinico S. Donato
IRCCS San Donato POliclinic, San Donato Milanese
Registry updated 2026-10-16
NCT07185009
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Trial Treatment · Phase 3 · Sanofi
Rome · Rozzano · Turin
Registry updated 2026-10-16
NCT06405087
A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Trial Treatment · Phase 3 · Takeda
Azienda Ospedaliera Universitaria Gaetano Martino Messina, Messina · ASST Fatebenefratelli Sacco, Milan · Azienda Sanitaria Locale di Pescara, Pescara · Ospedale Pediatrico Bambino Gesù, Rome
Registry updated 2026-10-09
2025-522338-30-00
LY4268989 (MORF-057) Co-Administered with Mirikizumab in Adults with Moderately to Severely Active Ulcerative Colitis: A Phase 2 Study
Trial Treatment · Phase 2 · Eli Lilly & Co.
ASST Grande Ospedale Metropolitano Niguarda, Milan · Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan · Ospedale San Raffaele S.r.l., Milan · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Humanitas Mirasole S.p.A., Rozzano
Registry updated 2026-10-07
NCT04844606
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Trial Treatment · Phase 3 · Eli Lilly and Company
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo · Ospedale Maggiore Azienda USL di Bologna, Bologna · Azienda Ospedaliera Universitaria Meyer IRCCS, Florence · Ospedale dei Bambini "Vittore Buzzi", Milan · AOU Policlinico Umberto I, Roma · Ospedale Pediatrico Bambino Gesu Irccs, Rome
Registry updated 2026-10-07

All Ulcerative colitis trials and the map

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