Clinical trials

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164 trials

NCT04166526
Recruiting
A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease
Not applicable · United States · 1 site
Registry update: 12 Dec 2025
NCT04008368
Recruiting
Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels
Phase 1/2 · United States · 1 site
Registry update: 26 Oct 2026
NCT04157179
Recruiting
Cerebral Oxygen Metabolism in Children
Not applicable · United States · 1 site
Registry update: 11 Sept 2025
NCT03937817
Recruiting
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants
Not applicable · United States · 1 site
Registry update: 2 Oct 2026
NCT03786549
Recruiting
Pediatric -Adult Care Transition Program of Patients With Sickle Cell Disease
Not applicable · France · 8 sites
Registry update: 21 Jun 2024
NCT03685721
Recruiting
Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease
Not applicable · United States · 1 site
Registry update: 10 Nov 2026
NCT03653338
Recruiting
T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias
Phase 1/2 · United States · 1 site
Registry update: 13 Aug 2026
NCT03587272
Recruiting
Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease
Phase 2 · Canada, United States · 7 sites
Registry update: 10 Mar 2026
NCT03353584
Recruiting
Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease
Not applicable · United States · 2 sites
Registry update: 18 May 2026
NCT03214354
Recruiting
Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor
Phase 2 · Canada · 1 site
Registry update: 1 May 2026
NCT02675959
Recruiting
Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease
Phase 2 · United States · 4 sites
Registry update: 27 Jul 2026
NCT03121001
Recruiting
Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease
Phase 2 · United States · 1 site
Registry update: 8 Jul 2026
NCT03128996
Recruiting
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
Phase 1/2 · United States · 4 sites
Registry update: 29 May 2026
NCT03327428
Recruiting
Sickle-cell Disease Registry of the GPOH
Not applicable · Germany · 1 site
Registry update: 24 Jan 2025
NCT06418256
Recruiting
Physiology and Pathologies Linked to Human Splenic Function : Direct and Ex-vivo Perfusion Explorations
Not applicable · France · 5 sites
Registry update: 15 Sept 2025
NCT02720679
Recruiting
Investigation of the Genetics of Hematologic Diseases
Not applicable · United States · 1 site
Registry update: 9 Jun 2026
NCT02447874
Recruiting
Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease
Phase 1/2 · United States · 2 sites
Registry update: 29 Jul 2026
NCT02824471
Recruiting
Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)
Not applicable · United States · 1 site
Registry update: 11 Sept 2026
NCT02098863
Recruiting
Sickle Cell Clinical Research and Intervention Program
Not applicable · United States · 6 sites
Registry update: 4 Jun 2026
NCT01962415
Recruiting
Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT
Phase 2 · United States · 1 site
Registry update: 15 Dec 2025

Ordered by registry start date. Freshness and sponsorship never change the order.