What does science say about Fasting and fasting-mimicking diet and Depression?
- We don’t say yes or no. We show what has been studied.
- Working in a lab or in animals does not mean it works in people.
- Don’t stop or change your treatment without talking to your doctor.
What has been studied
- Lab studies (cells)Tests on cells in a dish.Source: PubMed · as of 5 Nov 2026 · Open the search at PubMed0studies
- Animal studiesTests in mice, rats or other animals.Source: PubMed · as of 5 Nov 2026 · Open the search at PubMed0studies
- Studies in peoplePublished studies with human participants.Source: PubMed · as of 5 Nov 2026 · Open the search at PubMed29studies
- Registered trials in peopleTrials entered in a public registry, whatever their result.ClinicalTrials.gov: 1 · as of 5 Nov 2026 · Open the search at ClinicalTrials.govEU CTIS: 1 · as of 5 Nov 2026 · Open the search at EU CTISBy phase:No phase (1)Phase 1 (1)By status:Not yet recruiting (2)Countries (2):Canada (1)Romania (1)With a linked publication (results): 0 of 2The registries do not tell us here whether results were posted; a linked publication is shown instead.2trials
- Approved treatmentApproved by a medicines regulator for this disease.No
Examples of what we found
The trials
Phase 1
An open label, balanced, randomized, two-treatment, two-period, two-sequence, single dose crossover, bioavailability study comparing Bupropion Hydrochloride Extended Release Capsules 150 mg, Manufactured by Sun Pharmaceutical Industries Limited, India with WELLBUTRIN XL (Bupropion hydrochloride) extended release tablets 300 mg, Distributed by: Bausch Health US, LLC Bridgewater, NJ 08807 USA. Manufactured by: Bausch Health Companies, Inc. Steinbach, MB R5G 1Z7, Canada, in healthy, adult, human subjects under fasting condition.
Not yet recruiting · Romania
EU CTIS · 2025-523410-84-00No phase
Intermittent Fasting for Inflammation and Depression in Spinal Cord Injury
Not yet recruiting · Canada
ClinicalTrials.gov · NCT06807528
Thinking of paying for it? Read this first
- Ask for published results. Stories, thank-you letters and "patients report" are not results. Ask where the results were published.
- Know what you pay for. Ask in writing: what exactly is included, who gets the money, and what happens if you stop.
- Ask your own doctor first. Some products interfere with chemotherapy, radiation or other medicines. Your treating doctor can check this.
- Do not stop standard treatment for it. Do not stop or delay your treatment without talking to your care team.
Other treatments people ask about
- Cannabis and cannabinoids (CBD, THC)Step: Large trials
- Curcumin (turmeric)Step: Large trials
- Fasting and fasting-mimicking dietStep: Large trials
- High-dose vitamin CStep: Large trials
- HyperthermiaStep: Large trials
- Ketogenic dietStep: Large trials
- MelatoninStep: Large trials
- MetforminStep: Large trials
- StatinsStep: Large trials
- Vitamin DStep: Large trials
Not medical advice. Talk to the care team before changing treatment.