What does science say about Metformin and High blood pressure?
- We don’t say yes or no. We show what has been studied.
- Working in a lab or in animals does not mean it works in people.
- Don’t stop or change your treatment without talking to your doctor.
What has been studied
- Lab studies (cells)Tests on cells in a dish.Source: PubMed · as of 9 Nov 2026 · Open the search at PubMed1study
- Animal studiesTests in mice, rats or other animals.Source: PubMed · as of 9 Nov 2026 · Open the search at PubMed47studies
- Studies in peoplePublished studies with human participants.Source: PubMed · as of 9 Nov 2026 · Open the search at PubMed76studies
- Registered trials in peopleTrials entered in a public registry, whatever their result.ClinicalTrials.gov: 5 · as of 9 Nov 2026 · Open the search at ClinicalTrials.govEU CTIS: 0 · as of 9 Nov 2026 · Open the search at EU CTISBy phase:No phase (2)Phase 1/2 (1)Phase 4 (1)Phase 3 (1)By status:Recruiting (2)Withdrawn before start (1)Completed (1)Running, not recruiting (1)Countries (5):Kazakhstan (1)Nigeria (1)Netherlands (1)Pakistan (1)United States (1)With a linked publication (results): 0 of 5The registries do not tell us here whether results were posted; a linked publication is shown instead.5trials
- Approved treatmentApproved by a medicines regulator for this disease.No
Examples of what we found
The trials
Phase 3
Preeclampsia Intervention Netherlands
Recruiting · Netherlands
ClinicalTrials.gov · NCT06452498No phase
Improving Cardiovascular Disease Diagnosis and Treatment in Kazakhstan Using Metabolic Correction With GLP-1 Drugs
Running, not recruiting · Kazakhstan
ClinicalTrials.gov · NCT07303556Phase 1/2
Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes Patients
Withdrawn before start · United States
ClinicalTrials.gov · NCT03686657
Thinking of paying for it? Read this first
- Ask for published results. Stories, thank-you letters and "patients report" are not results. Ask where the results were published.
- Know what you pay for. Ask in writing: what exactly is included, who gets the money, and what happens if you stop.
- Ask your own doctor first. Some products interfere with chemotherapy, radiation or other medicines. Your treating doctor can check this.
- Do not stop standard treatment for it. Do not stop or delay your treatment without talking to your care team.
Other treatments people ask about
- Cannabis and cannabinoids (CBD, THC)Step: Large trials
- Curcumin (turmeric)Step: Large trials
- Fasting and fasting-mimicking dietStep: Large trials
- High-dose vitamin CStep: Large trials
- Ketogenic dietStep: Large trials
- MelatoninStep: Large trials
- MetforminStep: Large trials
- StatinsStep: Large trials
- Vitamin DStep: Large trials
- Dichloroacetate (DCA)Step: First trials in people
- Mistletoe extractStep: First trials in people
- HyperthermiaStep: Reports in people
- FenbendazoleStep: Animal studies only
Not medical advice. Talk to the care team before changing treatment.