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What science says

What does science say about Statins and Familial hypercholesterolaemia?

  • We don’t say yes or no. We show what has been studied.
  • Working in a lab or in animals does not mean it works in people.
  • Don’t stop or change your treatment without talking to your doctor.

What has been studied

  1. Lab studies (cells)Tests on cells in a dish.Source: PubMed · as of 9 Nov 2026 · Open the search at PubMed76studies
  2. Animal studiesTests in mice, rats or other animals.Source: PubMed · as of 9 Nov 2026 · Open the search at PubMed289studies
  3. Studies in peoplePublished studies with human participants.Source: PubMed · as of 9 Nov 2026 · Open the search at PubMed1774studies
  4. Registered trials in peopleTrials entered in a public registry, whatever their result.ClinicalTrials.gov: 22 · as of 9 Nov 2026 · Open the search at ClinicalTrials.govEU CTIS: 2 · as of 9 Nov 2026 · Open the search at EU CTISBy phase:No phase (7)Phase 4 (6)Phase 3 (5)Phase 1 (3)Phase 2 (3)By status:Completed (10)Not yet recruiting (6)Recruiting (4)Running, not recruiting (2)Withdrawn before start (1)By invitation only (1)Countries (20):United States (7)South Korea (6)Spain (3)United Kingdom (3)Italy (3)Germany (2)Pakistan (2)Argentina (1)Austria (1)Australia (1)Bangladesh (1)Belgium (1)Brazil (1)Canada (1)China (1)Hungary (1)Israel (1)Netherlands (1)Norway (1)New Zealand (1)With a linked publication (results): 1 of 24The registries do not tell us here whether results were posted; a linked publication is shown instead.24trials
  5. Approved treatmentApproved by a medicines regulator for this disease.No

Source: PubMed, ClinicalTrials.gov, EU CTIS · as of 9 Nov 2026

Examples of what we found

The trials

  7. Phase 3

    A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

    Running, not recruiting · Argentina, Australia, Brazil, Canada, Spain, United Kingdom, Hungary, Israel, New Zealand, United States

    ClinicalTrials.gov · NCT07216482

Thinking of paying for it? Read this first

  • Ask for published results. Stories, thank-you letters and "patients report" are not results. Ask where the results were published.
  • Know what you pay for. Ask in writing: what exactly is included, who gets the money, and what happens if you stop.
  • Ask your own doctor first. Some products interfere with chemotherapy, radiation or other medicines. Your treating doctor can check this.
  • Do not stop standard treatment for it. Do not stop or delay your treatment without talking to your care team.

Before you pay for a treatment

Other treatments people ask about

Not medical advice. Talk to the care team before changing treatment.

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Under construction, not live – What does science say about Statins and Familial hypercholesterolaemia? – Frontlight Research