Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.
What people read
Posts online say that Stem cell treatment helps with Ankylosing spondylitis.
What has been studied
- 1In people
- 10In animals
- 21Only in the lab
What the studies found
Stem cell treatment has been studied in people with Ankylosing spondylitis, but not in randomised trials.
We found 63 published papers on Stem cell treatment and Ankylosing spondylitis. They were published between 2000 and 2026.
1 of them are studies in people (0 randomised trials), 8 are reviews, 10 are studies in animals and 21 are studies only in the lab. 1 paper was retracted.
The most important ones are listed under Sources.
What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- Effects and safety of allogenic mesenchymal stem cell intravenous infusion in active ankylosing spondylitis patients who failed NSAIDs: a 20-week clinical trial.2014 · Cell Transplant · Study in people
- Breaking boundaries in ankylosing spondylitis: how innovative cell therapies reshape immunity, drive cutting-edge advances, and face future challenges.2025 · Front Immunol · Review
- Efficacy and safety of culture-expanded mesenchymal stromal cell therapy in the treatment of 4 types of inflammatory arthritis: A systematic review and meta-analysis of 36 randomized controlled trials.2024 · Semin Arthritis Rheum · Review
- Mesenchymal Stem Cells in Heterotopic Ossification in Ankylosing Spondylitis: A Bibliometric Study Based on CiteSpace and VOSViewer.2023 · J Inflamm Res · Review
- Impact of immune regulation and differentiation dysfunction of mesenchymal stem cells on the disease process in ankylosing spondylitis and prospective analysis of stem cell transplantation therapy.2023 · Postgrad Med J · Review
- Biology and therapeutic potential of mesenchymal stem cell extracellular vesicles in axial spondyloarthritis.2023 · Commun Biol · Review
- Efficacy and Safety of Mesenchymal Stem Cell Transplantation in the Treatment of Autoimmune Diseases (Rheumatoid Arthritis, Systemic Lupus Erythematosus, Inflammatory Bowel Disease, Multiple Sclerosis, and Ankylosing Spondylitis): A Systematic Review and Meta-Analysis of Randomized Controlled Trial.2022 · Stem Cells Int · Review
- Circ_0018814 promotes the osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis by regulating the miR-944/KLF4 axis.2026 · J Mol Histol · In animals
- Single-cell RNA sequencing identifies PD-L1 + mesenchymal stem cells with enhanced immunomodulatory capacity and alleviated the degree of ectopic new bone formation in ankylosing spondylitis.2025 · Stem Cell Res Ther · In animals
- Integrin-linked kinase-mediated promotion of osteogenic differentiation in bone marrow mesenchymal stem cells: A driver of heterotopic ossification in ankylosing spondylitis.2025 · Bone · In animals
- Excessive accumulation of thioredoxin promotes osteogenic differentiation of mesenchymal stem cells of ligament in ankylosing spondylitis by upregulating autophagy levels.2025 · Biochem Biophys Res Commun · In animals
- Evaluation of preclinical efficacy of human umbilical cord mesenchymal stem cells in ankylosing spondylitis.2023 · Front Immunol · In animals
- MEG3 alleviates ankylosing spondylitis by suppressing osteogenic differentiation of mesenchymal stem cells through regulating microRNA-125a-5p-mediated TNFAIP3.2023 · Apoptosis · In animals
- Significant correlations of upregulated MPO expression with cytokine imbalance in ankylosing spondylitis patients and the inhibitory effect mediated by mesenchymal stem cells.2025 · BMC Musculoskelet Disord · In the lab
- Generation of induced pluripotent stem cells from an HLA-B27 positive ankylosing spondylitis patient with syndesmophyte formation.2024 · Stem Cell Res · In the lab
- [Role of intercellular adhesion molecule-1 in adhesion and migration of mesenchymal stem cells in ankylosing spondylitis and its mechanisms].2024 · Zhonghua Yi Xue Za Zhi · In the lab
- CD_99 G1 neutrophils modulate osteogenic differentiation of mesenchymal stem cells in the pathological process of ankylosing spondylitis.2024 · Ann Rheum Dis · In the lab
- Reduced immunomodulation potential of bone marrow-derived mesenchymal stem cells induced CCR4+CCR6+ Th/Treg cell subset imbalance in ankylosing spondylitis.2011 · Arthritis Res Ther · RetractedRetracted
- Single-cell profiling reveals senescent bone marrow mesenchymal stem cell subpopulations driving pathological ossification in ankylosing spondylitis.2026 · Rheumatology (Oxford) · Other paper
- Sequential Clinical Changes Following Autologous Mesenchymal Stem Cell Therapy in a Patient With Concurrent Huntington's Disease and Ankylosing Spondylitis: A Case Report.2026 · Cureus · Other paper
- YTHDF3 regulates IL32 mRNA stability to promote osteogenic differentiation of bone mesenchymal stem cells in ankylosing spondylitis.2025 · J Transl Med · Other paper
- Fat mass and obesity-associated protein in mesenchymal stem cells inhibits osteoclastogenesis via lnc NORAD/miR-4284 axis in ankylosing spondylitis.2025 · World J Stem Cells · Other paper