Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.
What people read
Posts online say that Stem cell treatment helps with Huntington's disease.
What has been studied
- 2In people1 randomised trial
- 12In animals
- 21Only in the lab
What the studies found
Stem cell treatment has been tested in randomised trials in people with Huntington's disease.
We found 90 published papers on Stem cell treatment and Huntington's disease. They were published between 2004 and 2026.
2 of them are studies in people (1 randomised trials), 49 are reviews, 12 are studies in animals and 21 are studies only in the lab.
The most important ones are listed under Sources.
What this means for you: A study in people is not proof that it helps you. Do not stop or change your medicines because of it. Ask your doctor before you start taking it.
Sources
- Phase II trial of intravenous human dental pulp stem cell therapy for Huntington's disease: a randomized, double-blind, placebo-controlled study.2025 · Stem Cell Res Ther · Randomised trial
- A phase I, open-label study of intravenous human dental pulp stem cells (NestaCell®) at two dose levels in patients with Huntington's disease.2025 · Stem Cell Res Ther · Study in people
- Insights into neurodevelopmental features of Huntington's disease from stem cell-derived models including organoids.2026 · J Huntingtons Dis · Review
- The Evolving Landscape of Stem Cell Therapies for Huntington's Disease.2026 · Mol Diagn Ther · Review
- Advances in Stem Cell Therapy for Huntington's Disease: A Comprehensive Literature Review.2025 · Cells · Review
- Perinatal Tissue-Derived Stem Cells: An Emerging Therapeutic Strategy for Challenging Neurodegenerative Diseases.2024 · Int J Mol Sci · Review
- Mesenchymal Stem Cell-Derived Extracellular Vesicles: An Emerging Diagnostic and Therapeutic Biomolecules for Neurodegenerative Disabilities.2023 · Biomolecules · Review
- Advances in stem cell and other therapies for Huntington's disease: An update.2023 · Brain Res Bull · Review
- Stem cells enhance mitochondrial function in experimental Huntington's disease.2026 · Stem Cells · In animals
- Clinical-Grade Human Induced Pluripotent Stem Cell-Derived Neural Precursor Cells Restore Motor Function and Preserve Striatal Integrity in a Quinolinic Acid-Lesioned Rat Model of Huntington's Disease.2026 · Cell Prolif · In animals
- Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington's disease mice and innervate the striatum.2023 · Mol Ther · In animals
- Restoration of BDNF, DARPP32, and D2R Expression Following Intravenous Infusion of Human Immature Dental Pulp Stem Cells in Huntington's Disease 3-NP Rat Model.2022 · Cells · In animals
- Transplantation of human dental pulp stem cells compensates for striatal atrophy and modulates neuro-inflammation in 3-nitropropionic acid rat model of Huntington's disease.2021 · Neurosci Res · In animals
- Bilateral striatal transplantation of human olfactory stem cells ameliorates motor function, prevents necroptosis-induced cell death and improves striatal volume in the rat model of Huntington's disease.2021 · J Chem Neuroanat · In animals
- Induced pluripotent stem cells from a transgenic minipig model of Huntington's disease reveal early metabolic changes.2026 · Dis Model Mech · In the lab
- Neuroprotective Effects of Transplanted Induced Pluripotent Stem Cell-Derived Neural Precursors in Huntington's Disease Models.2026 · Int J Stem Cells · In the lab
- Generation of four induced pluripotent stem cell lines from Korean patients with Huntington's disease (IPBi001-A, IPBi002-A, IPBi003-A, IPBi004-A).2026 · Stem Cell Res · In the lab
- Biallelic genome engineering to create isogenic induced pluripotent stem cells modeling Huntington's disease.2025 · Genes Genet Syst · In the lab
- Sequential Clinical Changes Following Autologous Mesenchymal Stem Cell Therapy in a Patient With Concurrent Huntington's Disease and Ankylosing Spondylitis: A Case Report.2026 · Cureus · Other paper
- Intersecting impact of CAG repeat and huntingtin knockout in stem cell-derived cortical neurons.2025 · Neurobiol Dis · Other paper
- Preparation of chaperone-loaded neural stem cell-derived extracellular vesicles to reduce protein aggregation in Huntington's disease cellular models.2023 · STAR Protoc · Other paper
- How can human pluripotent stem cells help decipher and cure Huntington's disease?2012 · Cell Stem Cell · Other paper