Stem cell treatment & Spinal muscular atrophy

Written from the studies on PubMed, searched on 2026. nov. 11.. Every number below comes from a study listed under Sources.

What people read

Posts online say that Stem cell treatment helps with Spinal muscular atrophy.

What has been studied

• 1In people
• 10In animals
• 19Only in the lab

What the studies found

!Stem cell treatment has been studied in people with Spinal muscular atrophy, but not in randomised trials.

We found 63 published papers on Stem cell treatment and Spinal muscular atrophy. They were published between 2006 and 2026.

1 of them are studies in people (0 randomised trials), 21 are reviews, 10 are studies in animals and 19 are studies only in the lab.

The most important ones are listed under Sources.

Sources

1. An open-label phase 1 clinical trial of the allogeneic side population adipose-derived mesenchymal stem cells in SMA type 1 patients.2022 · Neurol Sci · Study in people
2. Current Progress in the Creation, Characterization, and Application of Human Stem Cell-derived in Vitro Neuromuscular Junction Models.2022 · Stem Cell Rev Rep · Review
3. Spinal Muscular Atrophy Modeling and Treatment Advances by Induced Pluripotent Stem Cells Studies.2019 · Stem Cell Rev Rep · Review
4. Prenatal transplantation of human amniotic fluid stem cells for spinal muscular atrophy.2018 · Curr Opin Obstet Gynecol · Review
5. [Neuronal cells derived from induced pluripotent stem cells to model motoneuron diseases].2016 · Biol Aujourdhui · Review
6. Clinical and molecular features and therapeutic perspectives of spinal muscular atrophy with respiratory distress type 1.2015 · J Cell Mol Med · Review
7. Pluripotent stem cell-based models of spinal muscular atrophy.2015 · Mol Cell Neurosci · Review
8. Targeted knockdown of Smn in muscle stem cells induces non-cell autonomous loss of motor neurons.2026 · Brain · In animals
9. Physiological Features of the Neural Stem Cells Obtained from an Animal Model of Spinal Muscular Atrophy and Their Response to Antioxidant Curcumin.2024 · Int J Mol Sci · In animals
10. Administration of adipose-derived stem cells extracellular vesicles in a murine model of spinal muscular atrophy: effects of a new potential therapeutic strategy.2024 · Stem Cell Res Ther · In animals
11. Prenatal transplantation of human amniotic fluid stem cell could improve clinical outcome of type III spinal muscular atrophy in mice.2021 · Sci Rep · In animals
12. CSF transplantation of a specific iPSC-derived neural stem cell subpopulation ameliorates the disease phenotype in a mouse model of spinal muscular atrophy with respiratory distress type 1.2019 · Exp Neurol · In animals
13. A Perturbed MicroRNA Expression Pattern Characterizes Embryonic Neural Stem Cells Derived from a Severe Mouse Model of Spinal Muscular Atrophy (SMA).2015 · Int J Mol Sci · In animals
14. Generation and characterization of human induced pluripotent stem cell line AUSCIi001-A from spinal muscular atrophy patient.2026 · Stem Cell Res · In the lab
15. An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy.2025 · Front Neurosci · In the lab
16. An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy.2025 · bioRxiv · In the lab
17. A spinal and bulbar muscular atrophy (SBMA) disease-specific human embryonic stem cell (hESC) line, UMICHe002-A/UM197-1.2024 · Stem Cell Res · In the lab
18. Correction: Administration of adipose-derived stem cells extracellular vesicles in a murine model of spinal muscular atrophy: effects of a new potential therapeutic strategy.2024 · Stem Cell Res Ther · Other paper
19. Mitochondria replacement from transplanted amniotic fluid stem cells: a promising therapy for non-neuronal defects in spinal muscular atrophy.2024 · Neural Regen Res · Other paper
20. Cell-Based Therapy for Spinal Muscular Atrophy.2020 · Adv Exp Med Biol · Other paper
21. Established Stem Cell Model of Spinal Muscular Atrophy Is Applicable in the Evaluation of the Efficacy of Thyrotropin-Releasing Hormone Analog.2016 · Stem Cells Transl Med · Other paper

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