Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
MiR-326 targets ETS1 to activate PI3K/Akt signaling and promote malignant phenotypes in gastric cancer cells.
2026. dec. 1.· Pakistan journal of pharmaceutical sciences· PUBMED
Publikáció
Modulation of G6PD-mediated Vitamin C Sensitivity in Small Cell Lung Cancer by the AKT/NRF2 axis.
2026. nov. 5.· The Journal of biological chemistry· PUBMED
Publikáció
Statement of Retraction: MACC1 regulates the AKT/STAT3 signaling pathway to induce migration, invasion, cancer stemness, and suppress apoptosis in cervical cancer cells.
2026. nov. 5.· Bioengineered· PUBMED
Publikáció
AKT is necessary for neuronal hypertrophy and epilepsy caused by Pten knockout.
2026. nov. 4.· Brain : a journal of neurology· PUBMED
Publikáció
Targeting the PI3K/Akt/eNOS Pathway in Atherosclerosis: From Mechanotransduction to Emerging Therapies.
2026. nov. 4.· The international journal of biochemistry & cell biology· PUBMED
Publikáció
Procyanidin B2 ameliorates osteoporosis by modulating osteoclast precursor differentiation through activation of the PI3K/Akt/Nrf2 axis.
2026. nov. 4.· Bone· PUBMED
Publikáció
Characterization of cancer stem-like cells derived from a single 4T1 murine triple-negative breast cancer cell: Involvement of Akt‒mTOR pathway in the proliferation and sphere formation.
2026. nov. 3.· Archives of biochemistry and biophysics· PUBMED
Publikáció
Exogenous tryptophan aggravates experimental lung fibrosis through activation of AKT-mTORC1 pathway.
2026. nov. 3.· PloS one· PUBMED
Publikáció
Suppression of AKT Activation through LZK Inhibition Limits Tumor Growth in Esophageal and Head and Neck Cancers.
2026. nov. 3.· Molecular cancer therapeutics· PUBMED
Publikáció
SALL4 drives gastric cancer progression through PI3K/Akt-mediated regulation of glycolysis, EMT, stemness, and adhesion remodeling.
2026. nov. 1.· Biochimica et biophysica acta. Gene regulatory mechanisms· PUBMED
Publikáció
Epigenetic silencing of PDLIM4 promotes colorectal cancer by impairing BTF3 autophagic degradation and activating PI3K/Akt signalling.
2026. nov. 1.· Clinical and translational medicine· PUBMED
Publikáció
Dendrobium officinale extract ameliorates Alzheimer's disease by modulating PI3K-AKT-mTOR pathway and autophagy-related processes: An integrated study combining feature-based molecular networking, network pharmacology and multi-omics.
2026. okt. 31.· Journal of ethnopharmacology· PUBMED
Publikáció
Mucolipin TRP Cation Channel 1 Depletion Promotes Gastric Cancer Cell Ferroptosis Through the AKT Pathway.
2026. okt. 31.· The Kaohsiung journal of medical sciences· PUBMED
Publikáció
SD-2102, a Novel PDK1 Inhibitor, Suppresses Lung Cancer Growth by Targeting PDK1/Akt Signaling Pathway.
2026. okt. 30.· Biomolecules & therapeutics· PUBMED
Publikáció
SLC2A1 promotes chemo-immunotherapy resistance in lung adenocarcinoma by modulating the AKT signaling pathway.
2026. okt. 28.· Functional & integrative genomics· PUBMED
Publikáció
AKT1-phosphorylated TERT assembles a FOXO3-MYC transcriptional complex that drives ERphagy and proteostasis in post-mitotic RPE.
2026. okt. 26.· Autophagy· PUBMED
Publikáció
Hydroxysafflor yellow A ameliorates progression of endometriosis via regulating PPAR-γ/PTEN/Akt axis.
2026. okt. 26.· Tissue & cell· PUBMED
Publikáció
Gentiopicroside suppresses cell proliferation, migration, and invasion via inhibition of the HGF/PI3K/Akt pathway in clear cell renal cell carcinoma.
2026. okt. 26.· Acta pharmaceutica (Zagreb, Croatia)· PUBMED
Publikáció
UFSP2 constitutes a targetable vulnerability via deUFMylation-dependent activation of AKT oncogenic signaling.
2026. okt. 26.· Cell reports· PUBMED
Publikáció
Transcutaneous auricular vagus nerve stimulation attenuates post-stroke dysphagia by modulating microglial polarization via the endothelial VWF/PI3K-Akt axis.
2026. okt. 25.· Brain research· PUBMED
Publikáció
The PHLPP paradox revisited: from canonical AKT phosphatases to signaling pseudoenzymes in human disease.
2026. okt. 25.· Biochemical pharmacology· PUBMED
Publikáció
Fufang Xianzhuli Ye attenuates airway inflammation and epithelial injury in experimental asthma: involvement of PI3K-Akt and PPAR-γ signaling and associated lipid metabolic changes.
2026. okt. 24.· Journal of natural medicines· PUBMED
Publikáció
Recombinant spinach ribosome-inactivating protein induces cytotoxicity and alters gene expression associated with PTEN/AKT/mTOR signaling, apoptosis, and stemness in HT29 cells.
2026. okt. 23.· European journal of pharmacology· PUBMED
Publikáció
Shikonin combined with curcumin synergistically induces apoptosis of glioma cells by inhibiting the PI3K/Akt/NF-κB signaling pathway.
2026. okt. 23.· Oncology letters· PUBMED
Publikáció
Licorice flavonoids ameliorate type 2 diabetes mellitus via modulation of the AMPK/mTORC1/AKT signaling network.
2026. okt. 22.· Journal of drug targeting· PUBMED
Publikáció
P2Y6 receptor activation promotes the migration, invasion and glycogen accumulation of colorectal cancer through AKT/mTOR signaling.
2026. okt. 22.· Tissue & cell· PUBMED
Publikáció
Author Correction: β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer.
2026. okt. 22.· Nature medicine· PUBMED
Publikáció
Yindan Xinnaotong Soft Capsule Ameliorates Parkinson's Disease and is Associated with Modulation of the AKT/MDM2/p53 Pathway: Network Pharmacology, Molecular Docking, and Experimental Validation.
2026. okt. 22.· CNS & neurological disorders drug targets· PUBMED
Publikáció
RETRACTION: The Mechanism of the Yigutang-Mediated P13K/AKT/GSK-3β Signal Pathway to Regulate Osteogenic Differentiation of Bone Marrow Stromal Stem Cells to Treat Osteoporosis.
2026. okt. 22.· Evidence-based complementary and alternative medicine : eCAM· PUBMED
Publikáció
WTAP/YTHDC1-mediated m6A modification of P4HA1 suppresses hepatic gluconeogenesis and ameliorates MASLD by activating AKT signaling.
2026. okt. 22.· Cellular signalling· PUBMED