Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
SLIT2 and ANGPTL3 as putative mediators linking obesity to atrial fibrillation: A Mendelian randomization study.
2026. júl. 3.· Medicine· PUBMED
Publikáció
Gene Silencing of ANGPTL3 Induces PCSK9: Exploring the Biological Significance in the Hepatoma Huh7 Cell Line.
2026. jún. 30.· Cells· PUBMED
Publikáció
Anti-ANGPTL3 antibody and IL-22 fusion protein mitigate nephrotic syndrome via mitochondrial protection, anti-apoptosis, and autophagy suppression.
2026. jún. 16.· Antibody therapeutics· PUBMED
Publikáció
Targeting ANGPTL3 and IL-33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis.
2026. máj. 19.· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publikáció
Promise of ANGPTL3 as a therapeutic target for controlling cholesterol levels.
2026. máj. 12.· Expert opinion on therapeutic targets· PUBMED
Publikáció
Correction: The ANGPTL3-integrin α5 axis drives retinal vascular leakage in diabetic retinopathy.
2026. máj. 9.· Journal of translational medicine· PUBMED
Publikáció
Associations of ANGPTL3/4/8 proteins and complexes with heart failure and heart failure mortality.
2026. máj. 7.· Lipids in health and disease· PUBMED
Publikáció
Apolipoprotein A2 Influences ANGPTL3 in Modulating TG Catabolism and Inflammatory Cytokines Secretion.
2026. máj. 4.· Current molecular medicine· PUBMED
Publikáció
ANGPTL3, Apo CIII, Leptin and Triglycerides Are Elevated in Metastatic Prostate Cancer.
2026. ápr. 7.· Cancers· PUBMED
Vizsgálat
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
2026. márc. 24.· PHASE1 · RECRUITING· CTGOV
Publikáció
Hepatocyte-Specific Knockout of YAP Protects Against Atherosclerosis via Inhibition of ANGPTL3 in Mice.
2026. febr. 26.· Arteriosclerosis, thrombosis, and vascular biology· PUBMED
Vizsgálat
A Dose-exploration Study of EDP167 in HoFH
2026. febr. 6.· PHASE2 · RECRUITING· CTGOV
Publikáció
ANGPTL3 in Podocytes Contributes to the Pathogenesis of Lupus Nephritis by Activating MSR1 in Macrophages.
2026. febr. 3.· Kidney diseases (Basel, Switzerland)· PUBMED
Publikáció
ANGPTL3 in the Peripheral Circulation Is Associated with Resistance to Anti-PD1 Therapy in Advanced Gastric Cancer.
2026. febr. 1.· Cancer research communications· PUBMED
Publikáció
Anti-ANGPTL3 Antibody SHR-1918 for Homozygous Familial Hypercholesterolemia: A Nonrandomized Clinical Trial.
2026. febr. 1.· JAMA cardiology· PUBMED
Publikáció
The ANGPTL3-integrin α5 axis drives retinal vascular leakage in diabetic retinopathy.
2026. jan. 19.· Journal of translational medicine· PUBMED
Publikáció
PCSK9 and ANGPTL3 Inhibitors in Homozygous Familial Hypercholesterolemia: A Meta-analysis of Randomized Clinical Trials.
2026. jan. 7.· Drugs· PUBMED
Publikáció
Does siRNA therapy against ANGPTL3 bring new hope in homozygous familial hypercholesterolaemia?
2025. dec. 18.· The lancet. Diabetes & endocrinology· PUBMED
Publikáció
Zodasiran, an RNAi therapeutic targeting ANGPTL3, for treating patients with homozygous familial hypercholesterolaemia (GATEWAY): an open-label, randomised, phase 2 trial.
2025. dec. 18.· The lancet. Diabetes & endocrinology· PUBMED
Publikáció
ANGPTL3 promotes colorectal carcinoma progression and metastasis through regulating COL1A2 transcription via interacting with integrin αVβ3.
2025. nov. 17.· Cancer letters· PUBMED
Publikáció
Phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3.
2025. nov. 8.· The New England journal of medicine· PUBMED
Publikáció
Digoxin targets BHLHE40 to inhibit epithelial-mesenchymal transition in cervical cancer cells via downregulation of ANGPTL3.
2025. nov. 5.· Journal of natural medicines· PUBMED