APP

Betegségek

• Alzheimer disease1 vizsgálat
• Coronary artery disease1 vizsgálat

Az elmúlt 24 hónap

Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.

VizsgálatokPublikációkPreprintekPályázatok

• Publikáció

  Overexpression of hippocampal AdipoR1 ameliorates cognitive dysfunction in APP/PS1 mice through inhibiting NLRP3-Mediated neuronal pyroptosis.

  2026. okt. 26.· Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics· PUBMED

• Publikáció

  Comment on "High-intensity interval training modulates APP expression and reduces neuronal apoptosis in a β-amyloid-induced model of Alzheimer's disease: hippocampal evidence".

  2026. okt. 20.· Experimental brain research· PUBMED

• Publikáció

  [Suanzaoren Decoction inhibits neuroinflammation and alleviates hippocampal neuronal injury in APP/PS1 transgenic mice by regulating the Hippo-YAP pathway].

  2026. okt. 20.· Nan fang yi ke da xue xue bao = Journal of Southern Medical University· PUBMED

• Publikáció

  miR‑660‑5p ameliorates neuronal damage in Alzheimer's disease via targeting APP.

  2026. okt. 17.· Neurogenetics· PUBMED

• Publikáció

  CXCL16-driven neutrophil extracellular traps promote osteoporosis in APP/PS1 mice by disrupting bone remodeling.

  2026. okt. 8.· Bone· PUBMED

• Publikáció

  Intranasal Artesunate Ameliorates Hippocampal LFP Abnormalities and Cellular Apoptosis in APP/PS1 Mice via a Mechanism Involving GHRH/PI3K/AKT Signaling.

  2026. okt. 6.· Molecular neurobiology· PUBMED

• Publikáció

  Correction: Comparing regional brain uptake of incretin receptor agonists after intranasal delivery in CD-1 mice and the APP/PS1 mouse model of Alzheimer's disease.

  2026. okt. 2.· Alzheimer's research & therapy· PUBMED

• Publikáció

  The influence of mutant genes APP and PSEN1 on hippocampal asymmetry in 5xFAD mice, transgenic model of Alzheimer disease.

  2026. okt. 1.· Vavilovskii zhurnal genetiki i selektsii· PUBMED

• Publikáció

  High-intensity interval training modulates APP expression and reduces neuronal apoptosis in a β-amyloid-induced model of Alzheimer's disease: hippocampal evidence.

  2026. szept. 25.· Experimental brain research· PUBMED

• Publikáció

  Humanized APP is the primary determinant of regional brain volume in humanized APOE knock-in mice: a cross-sectional ex vivo MRI study.

  2026. szept. 24.· Alzheimer's & dementia (New York, N. Y.)· PUBMED

• Publikáció

  Shenghui Decoction ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via modulation of the HMGB1/TLR4/NLRP3 pathway.

  2026. szept. 24.· Journal of ethnopharmacology· PUBMED

• Publikáció

  Integrated multi-omics identifies lineage-dependent myeloid cells recruitment and the APP-CD74 axis as an immunoregulatory target in pediatric high-grade glioma.

  2026. szept. 22.· Acta neuropathologica· PUBMED

• Publikáció

  Tinosinenside A ameliorates Alzheimer's disease-related pathology in APP/PS1 mice, accompanied by reduced neuroinflammation and altered microglial phenotype-associated marker expression.

  2026. szept. 22.· Naunyn-Schmiedeberg's archives of pharmacology· PUBMED

• Publikáció

  D-Cycloserine ameliorates innate fear deficits in young adult male APP/PS1 mice: Involvement of GluN2B-containing NMDA receptor.

  2026. szept. 19.· Pharmacology, biochemistry, and behavior· PUBMED

• Publikáció

  A coordinated multi-target approach based on chondroitin sulphate nano-selenium mitigates Alzheimer's disease pathologies in APP/PS1 mice.

  2026. szept. 15.· Frontiers in pharmacology· PUBMED

• Publikáció

  Nrf2 overexpression ameliorates cognitive deficits and neuronal damage in APP/PS1 mice via attenuation of Aβ deposition and neuronal ferroptosis.

  2026. szept. 13.· Neuroscience letters· PUBMED

• Publikáció

  Correlations of PSEN1, PSEN2, and APP missense variants on the production of Aβ peptides against variant effect prediction.

  2026. szept. 7.· Alzheimer's & dementia (New York, N. Y.)· PUBMED

• Preprint

  Histone Deacetylase Inhibitors Improve Memory Function and Decrease Neuropathology in APP/PS1 Mice.

  2026. aug. 26.· Research square· PUBMED

• Publikáció

  LAMTOR1 sorts APP to late endosomes via AP-3-mediated trafficking.

  2026. aug. 26.· Journal of molecular cell biology· PUBMED

• Preprint

  Hepatic and Brain Spatial Gene Expression Changes in Intragastric Alcohol Fed APP/PS1 Alzheimer's Disease Mouse Model.

  2026. aug. 24.· Research square· PUBMED

• Publikáció

  Liuwei Dihuang pills attenuates cognitive dysfunction in APP/PS1 mice through restoring mitochondrial homeostasis and activating the IRS/AKT/GSK3β insulin signaling pathway.

  2026. aug. 20.· Frontiers in pharmacology· PUBMED

• Publikáció

  Isoserine Improves Spatial Memory and Remodels Synaptic and Inflammatory Gene-Expression Programs in APP/PS1 Mice.

  2026. aug. 18.· Cells· PUBMED

• Publikáció

  Oral administration of melatonin modulates macrophage polarization via modulating the Vegf signaling pathway and ameliorates Alzheimer's disease in APP/PS1 mice.

  2026. aug. 17.· Brain research bulletin· PUBMED

• Publikáció

  TP53 status is associated with differential stress-marker expression and APP maturation in colon cancer cells.

  2026. aug. 11.· Molecular biology reports· PUBMED

• Publikáció

  Adaptive-to-maladaptive IRE1α signaling as a driver of amyloidogenic APP processing in Alzheimer's disease.

  2026. aug. 11.· Frontiers in molecular biosciences· PUBMED

• Preprint

  APP Dosage and Extracellular Domain Variants Drive Distinct Defects in Neurogenesis modeled in Down Syndrome iPS cells.

  2026. aug. 6.· bioRxiv : the preprint server for biology· PUBMED

• Publikáció

  Distinct amyloid-β filament fold in individuals with APP Flemish mutation.

  2026. aug. 6.· Nature structural & molecular biology· PUBMED

• Publikáció

  Alzheimer's disease-linked Flemish APP mutation defines a distinct amyloid-β fold.

  2026. aug. 1.· Nature structural & molecular biology· PUBMED

• Publikáció

  APOE and genetic risk variants influence Alzheimer's disease onset in carriers of an extra copy of APP, with and without Down syndrome.

  2026. aug. 1.· Alzheimer's & dementia : the journal of the Alzheimer's Association· PUBMED

• Publikáció

  EV-transferred miR-7111-3p inhibits malignant phenotypes and tumor growth in nasopharyngeal carcinoma via targeting APP-regulated epithelial-mesenchymal transition.

  2026. júl. 30.· Journal of translational medicine· PUBMED

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