Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
Gramine Alleviates Ulcerative Colitis by Targeting COX-2 and Inhibiting Ferroptosis.
2026. nov. 4.· Journal of ethnopharmacology· PUBMED
Publikáció
Protective effects of melatonin against bisphenol A-mediated endometrial tumorigenesis: An experimental study targeting COX-2-dependent MMP-9 expression.
2026. nov. 1.· Taiwanese journal of obstetrics & gynecology· PUBMED
Publikáció
Integrated Transcriptomic and Network Pharmacology Identifies IRF1, PTGS2, TNF, and IFNG as Candidate Targets of Cortex Dictamni in Atopic Dermatitis.
2026. okt. 23.· Journal of visualized experiments : JoVE· PUBMED
Publikáció
Overcoming primary non-response to infliximab in ulcerative colitis: monocyte-derived PTGS2 as a therapeutic target.
2026. okt. 20.· Frontiers in immunology· PUBMED
Publikáció
Integrative network toxicology and pharmacology reveal that kaempferol alleviates BaP-triggered pulmonary fibrosis via suppressing Ras/COX-2-dependent cellular senescence.
2026. okt. 15.· Frontiers in pharmacology· PUBMED
Publikáció
Novel acetophenonic-isoxazoline derivatives with potent anti-cancer and selective COX-2 inhibitory effects: Design, synthesis, and biological evaluation.
2026. okt. 14.· Bioorganic chemistry· PUBMED
Publikáció
PTGS2/COX-2 is associated with neurovascular and blood-brain barrier changes in behaviourally classified MRL/lpr mice.
2026. okt. 12.· Lupus science & medicine· PUBMED
Vizsgálat
Intensive Locoregional Chemoimmunotherapy, Intradermal Autologous Alpha-DC1 Vaccines, and Systemic Pembrolizumab for Advanced-Stage Ovarian Cancer
2026. okt. 1.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publikáció
More Than Pain Relief: COX-2 Inhibitors and the Disease-Modifying Promise of NSAIDs in Axial Spondyloarthritis.
2026. okt. 1.· International journal of rheumatic diseases· PUBMED
Publikáció
Novel Pyrazole-4-Carbaldehyde Derivatives Having Potent COX-2 Inhibition and Anti-Tubercular Activity: Microwave-Assisted Green Synthesis and Molecular Docking.
2026. okt. 1.· Journal of biochemical and molecular toxicology· PUBMED
Publikáció
Systems Toxicology Indicates AKT1/PTGS2-Centered Neuroinflammatory-Mitochondrial Crosstalk in Lidocaine Associated Neurotoxicity.
2026. okt. 1.· CNS neuroscience & therapeutics· PUBMED
Publikáció
The deubiquitinating enzyme USP42 promotes lung adenocarcinoma progression through PTGS2.
2026. szept. 26.· Journal of molecular histology· PUBMED
Publikáció
Integrative computational analysis of public fecal lipidomics and transcriptomics datasets suggests a candidate association between the COX-2 pathway and CE(20:4) in colorectal adenoma-carcinoma progression.
2026. szept. 25.· PloS one· PUBMED
Publikáció
Integrated AUF-UPLC-MS and fraction-activity correlation to identify COX-2-targeted constituents of Shaoyao Gancao decoction.
2026. szept. 21.· Frontiers in chemistry· PUBMED
Publikáció
Integrative Perspectives on COX-2 Signaling and Selective Inhibitors in Central Nervous System Disorders: A Narrative Review.
2026. szept. 18.· Current medicinal chemistry· PUBMED
Publikáció
Therapeutic targeting of IL-17A-driven PTGS2/NLRP3 inflammasome activation in juvenile myelomonocytic leukemia.
2026. szept. 17.· Blood· PUBMED
Publikáció
Quercetin Alleviates Ferroptosis-Induced Renal Fibrosis by Modulating the PRDM9/HMOX1/PTGS2 Axis.
2026. szept. 16.· ACS omega· PUBMED
Publikáció
Inhibition of COX-2-Mediated Arachidonic Acid Metabolism by FGF21-PPARα Axis Alleviates Liver Steatosis.
2026. szept. 15.· MedComm· PUBMED
Publikáció
6PPDQ exposure enhances susceptibility to ulcerative colitis by disturbing MMP9, PTGS2, and PPARG homeostasis: an integrative network toxicology and in vivo study.
2026. szept. 12.· Chemico-biological interactions· PUBMED
Publikáció
Mitochondria-mediated anticancer effects of two previously characterized COX-2 inhibitors in hepatocellular carcinoma.
2026. szept. 11.· Molecular and cellular biochemistry· PUBMED
Publikáció
H3K18la facilitates nasopharyngeal carcinoma progression through the activation of the IGF2BP1-COX2 signaling pathway.
2026. szept. 8.· Frontiers in immunology· PUBMED
Publikáció
Anticancer Efficacy of HPPH-PDT Synergies with BCG-Immunotherapy or COX-2 Inhibitor in Treating Bladder Cancer.
2026. szept. 7.· Molecular pharmaceutics· PUBMED
Publikáció
Development of Phenoxyacetic Acid Hybrids With COX-2 Inhibitory Activity as Potential Anti-Neuroinflammatory Agents.
2026. szept. 1.· Drug development research· PUBMED
Publikáció
COX-2 Expression in Paired Primary Tumors and Lymph Node Metastases: An Exploratory Clinicopathological Study.
2026. aug. 24.· Cancers· PUBMED
Publikáció
Imaging-guided COX-2 inhibition synergizes with photodynamic immunogenic cell death to potentiate checkpoint blockade in colon cancer.
2026. aug. 18.· International journal of pharmaceutics: X· PUBMED
Publikáció
The CXCL5/CXCR2 Axis Attenuates Ferroptosis in Intrahepatic Cholangiocarcinoma Through the Positive Feedback Loop Between PTGS2 Transcriptional Activation and Neutrophil Recruitment.
2026. aug. 17.· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publikáció
Glycosylated Delphinidins, Natural Antioxidants, Functionally Modulate the COX-2/PGE2 Axis and Downregulate MDR1 in Glioblastoma Cells.
2026. aug. 13.· Antioxidants (Basel, Switzerland)· PUBMED
Publikáció
MLN4924 suppresses pancreatic cancer progression and enhances chemosensitivity to gemcitabine by targeting the PTGS2/EGFR-PI3K/Akt/mTOR signaling axis.
2026. aug. 11.· Anti-cancer drugs· PUBMED
Publikáció
BMSCs-AML cell interaction drives FLT3 inhibitor resistance through the NR2F2/COX-2/PGE2 Axis.
2026. aug. 11.· Cellular signalling· PUBMED
Publikáció
Borneol exerts an enhanced anti-tumor effect on triple-negative breast cancer by targeting PTGS2 to reinforce gemcitabine-induced DNA damage.
2026. aug. 3.· The Journal of pharmacy and pharmacology· PUBMED