Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Vizsgálat
Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms
2026. nov. 11.· PHASE1_PHASE2 · RECRUITING· CTGOV
Publikáció
Motor neuron disease and parkinsonism in a patient with a pathogenic CSF1R variant.
2026. okt. 26.· Revue neurologique· PUBMED
Publikáció
Marked intrafamilial phenotypic heterogeneity associated with the CSF1R c.2539G>A pathogenic variant in a Japanese family.
2026. okt. 14.· Journal of neural transmission (Vienna, Austria : 1996)· PUBMED
Publikáció
Inhibition of adipocyte-macrophage interaction via CSF1-CSF1R by curcumin.
2026. okt. 8.· Journal of physiology and biochemistry· PUBMED
Publikáció
Targeting IGF2BP3-driven CSF1/CSF1R signaling disrupts the positive feedback loop between tumor cells and macrophages and inhibits HCC progression.
2026. szept. 16.· Life sciences· PUBMED
Publikáció
Discovery of oxazole-capped 4-phenoxypiperidine CSF1R type II inhibitors with potent in vivo anti-rheumatoid arthritis activity.
2026. szept. 8.· Bioorganic chemistry· PUBMED
Publikáció
WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A-Mediated Regulation of CSF1R Signaling in Estrogen-Deficient Osteoporosis.
2026. aug. 30.· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publikáció
A CSF-1R Ig4-5 Domain-Targeting Antibody for the Treatment of Idiopathic Pulmonary Fibrosis.
2026. aug. 11.· Antibodies (Basel, Switzerland)· PUBMED
Publikáció
CSF1R Inhibition with Chemotherapy Relieves Systemic Immune Suppression in Patients with Metastatic Triple-Negative Breast Cancer and Boosts Anti-PD-1 Efficacy in Transgenic Mammary Tumors.
2026. júl. 17.· Clinical cancer research : an official journal of the American Association for Cancer Research· PUBMED
Publikáció
Dual inhibition of CSF-1R and IDO modulates the fibrotic and immunosuppressive tumor microenvironment in pancreatic ductal adenocarcinoma.
2026. júl. 15.· Frontiers in immunology· PUBMED
Publikáció
CSF1R inhibition exacerbates gamma oscillation disruption and induces network hyperexcitability in APP/PS1 mice.
2026. júl. 14.· Brain : a journal of neurology· PUBMED
Publikáció
CSF1R inhibition following antibody mediated demyelination has limited impact on remyelination.
2026. júl. 9.· Acta neuropathologica communications· PUBMED
Publikáció
Regional mapping of CSF1R-positive microglia in neurodegenerative diseases and progressive MS, with exploratory presynaptic marker analyses.
2026. júl. 4.· Journal of neuroinflammation· PUBMED
Publikáció
Highlighting the CSF1R mutational spectrum: c.2549C>T variant in late-onset leukoencephalopathy mimicking multiple sclerosis.
2026. jún. 24.· Neurologia i neurochirurgia polska· PUBMED
Publikáció
H3K18 lactylation promotes allergic airway inflammation in asthma via a CSF1/CSF1R/MAPK autocrine axis.
2026. jún. 23.· Respiratory research· PUBMED
Publikáció
Genetic screening for CSF1R variants in patients with dementia, parkinsonism, and multiple sclerosis.
2026. jún. 11.· Neurologia i neurochirurgia polska· PUBMED
Publikáció
Analysis of the Oncogenic Role of Colony-Stimulating Factor 1 Receptor (CSF1R) in Pancreatic Adenocarcinoma.
2026. jún. 9.· Anti-cancer agents in medicinal chemistry· PUBMED
Publikáció
CSF-1R inhibition and lenalidomide synergize to promote myeloma control after autologous stem cell transplantation.
2026. jún. 4.· Blood· PUBMED
Vizsgálat
ASTRAEA: ReinvigorAting ReSponse To ImmunotheRApy in MEtAstatic TNBC With Combination Myeloid Inhibition and Radiation
2026. jún. 1.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publikáció
CSF1R-dependent CD169-positive macrophages locally constrain melanoma growth in the skin.
2026. máj. 21.· The Journal of experimental medicine· PUBMED
Publikáció
Single-photon emission computed tomography 123I-ioflupane imaging in CSF1R mutation carriers.
2026. ápr. 16.· Neurologia i neurochirurgia polska· PUBMED
Publikáció
Discovery of novel CSF1R inhibitor for triple-negative breast cancer (TNBC) treatment through TAMs reprogramming.
2026. ápr. 16.· Biochemical pharmacology· PUBMED
Publikáció
Novel Insights into the Pathogenic Role of CSF1R in Endometriosis.
2026. ápr. 14.· Reproductive sciences (Thousand Oaks, Calif.)· PUBMED
Preprint
Serial Thermal Ablation Induces Abscopal Antitumor Immunity and Reveals Targetable CSF1R-Dependent Resistance in Pancreatic Cancer.
2026. ápr. 8.· bioRxiv : the preprint server for biology· PUBMED
Publikáció
Immune cell clustering identifies a CD163⁺/CSF1R⁺ macrophage and neutrophil-enriched phenotype with distinct biological signatures and poor prognosis in angiosarcoma.
2026. márc. 23.· Oncoimmunology· PUBMED
Publikáció
Safety and immunologic impact of neoadjuvant/adjuvant GVAX, cyclophosphamide, pembrolizumab, and anti-CSF1R agent IMC-CS4 in pancreatic adenocarcinoma.
2026. márc. 9.· Frontiers in immunology· PUBMED
Publikáció
The impact of CSF1R inhibitor-mediated microglial depletion in rodent models of Alzheimer's and Parkinson's disease: a systematic review and meta-analysis.
2026. febr. 25.· Frontiers in aging neuroscience· PUBMED
Publikáció
Colorectal cancer-derived osteopontin rewires macrophages into a pro-metastatic M2 state via the PI3K/AKT/CSF1-CSF1R axis.
2026. febr. 5.· Cell death discovery· PUBMED
Publikáció
CSF1R mutations in an Italian population of early-onset dementia: a case series.
2026. febr. 4.· Journal of neurology· PUBMED
Publikáció
Systemic CSF1R Targeting Depletes Pathogenic MPS Bubs and Ameliorates Psoriasis via PPARα-mediated Resolution.
2026. jan. 30.· Theranostics· PUBMED