Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
Clinical Study Protocol for PENTILULA: A Phase 1/2 Study Assessing [177Lu]Lu-Pentixather for Relapsed or Refractory CXCR4-Positive Acute Leukemia.
2026. nov. 5.· Journal of nuclear medicine : official publication, Society of Nuclear Medicine· PUBMED
Publikáció
Network Medicine Identifies a FOSL1/SNAI1-CCND1/CXCR4 Network Associated with N-Methyl-N'-nitro-N-nitrosoguanidine-Related Gastric Precancerous Lesions and Modulated by Apigenin.
2026. nov. 2.· Chemico-biological interactions· PUBMED
Publikáció
Autoimmune-shared immune states converge in a CXCL12-CXCR4 fibroblast-immune niche in chronic antibody-mediated rejection.
2026. nov. 2.· Signal transduction and targeted therapy· PUBMED
Publikáció
Clinical and immunological correlates of CXCR4 coreceptor use in people with HIV-1 receiving antiretroviral therapy in the Netherlands: a multicentre cohort study.
2026. okt. 29.· The Lancet. Microbe· PUBMED
Publikáció
CXCR4-dependent migratory differences between peripheral Tregs and Tcons preserve GVL while limiting GVHD after HSCT.
2026. okt. 27.· Blood advances· PUBMED
Publikáció
Lipopolysaccharide increases cell migration and invasion via NF-κB-mediated upregulation of CXCR4 in gallbladder cancer.
2026. okt. 26.· Medical oncology (Northwood, London, England)· PUBMED
Vizsgálat
U69-CART-Cells For R/R T-ALL
2026. okt. 25.· PHASE1 · RECRUITING· CTGOV
Publikáció
Multi-omics analysis of high-grade serous ovarian cancers reveals heterogeneity and distinct immunological patterns based upon clinico-genomic status.
2026. okt. 22.· PLoS genetics· PUBMED
Publikáció
FATP5 loss in hepatocellular carcinoma cells orchestrates tumor-promoting microenvironment by inducing passive long-chain fatty acid accumulation within tumor-associated endothelial cells.
2026. okt. 22.· Oncogene· PUBMED
Vizsgálat
Base-Edited Hematopoietic Stem/Progenitor Cell Gene Therapy for Treatment of CXCR4-WHIM
2026. okt. 21.· PHASE1_PHASE2 · ENROLLING_BY_INVITATION· CTGOV
Publikáció
Acetaldehyde Dehydrogenase 2 Remodels the Tumor Immune Microenvironment via CXCR4-CXCL12 Signaling in Head and Neck Squamous Cell Carcinoma.
2026. okt. 21.· The Journal of biological chemistry· PUBMED
Publikáció
Non-coding RNA networks remodeling metastatic signaling in the lung cancer microenvironment: a focus on TGF-β signaling and its crosstalk with Wnt/β-catenin, HIF, Notch, integrin, and CXCL12/CXCR4 pathways.
2026. okt. 19.· Cancer treatment and research communications· PUBMED
Publikáció
Dose-dependent CXCR4 inhibition in ovarian cancer cellular models reveals a paradoxical response characterized by subtype-specific oncogenic suppression and stress-induced adaptive rebound.
2026. okt. 16.· Molecular biology reports· PUBMED
Publikáció
A Multivariate Statistics Approach to Analyze the Transition from CCR5 to Dual and CXCR4 Tropism and to Predict the Coreceptor Usage of HIV-1.
2026. okt. 16.· Current HIV research· PUBMED
Publikáció
FOXC2 regulates macrophage polarization and osteosarcoma progression via the CXCL12/CXCR4 signaling axis.
2026. okt. 15.· The Journal of pathology· PUBMED
Publikáció
A Curated Phenotype-Linked HIV-1 Sequence Dataset for Machine Learning Approaches to Tropism Prediction, Disease Progression and Proviral Reservoir Studies.
2026. okt. 14.· Viruses· PUBMED
Publikáció
Computational identification of natural CXCR4-binding candidates relevant to endometriosis and ovarian cancer progression.
2026. okt. 7.· PloS one· PUBMED
Publikáció
A Dual-Action CXCR4-Targeted Peptide-Drug Conjugate Engineered to Enhance Antitumor Efficacy and Mitigate Myelosuppression in Pancreatic Cancer.
2026. okt. 5.· Molecular pharmaceutics· PUBMED
Vizsgálat
Evaluation of the Value of [68Ga]Ga-PENTIXAFOR PET-CT in Patients With Metastatic Small Cell Lung Cancer (SCLC)
2026. szept. 30.· EARLY_PHASE1 · NOT_YET_RECRUITING· CTGOV
Publikáció
Gene expression analysis after BTK and PI3Kδ inhibitor treatment in chronic lymphocytic leukemia identifies cell-surface CXCR4 as a synergistic target for combinatorial therapy.
2026. szept. 25.· HemaSphere· PUBMED
Publikáció
Neoadjuvant chemotherapy interferes with tertiary lymphoid structure formation in Epstein-Barr virus-associated gastric cancer.
2026. szept. 23.· Nature communications· PUBMED
Publikáció
Engineered polymeric systems suppress breast cancer metastasis by manipulating the clustering states of cell surface C-X-C chemokine receptor 4.
2026. szept. 20.· Journal of controlled release : official journal of the Controlled Release Society· PUBMED
Publikáció
GOLPH3-mediated sialylation of CXCR4 drives malignant progression and M2 macrophage polarization in colorectal cancer.
2026. szept. 16.· Apoptosis : an international journal on programmed cell death· PUBMED
Publikáció
C-X-C Motif Chemokine Receptor 4 (CXCR4)-Targeted Biologically Guided Proton Spatially Fractionated Radiotherapy for Bulky Limited-Stage Small Cell Lung Cancer.
2026. szept. 12.· Precision radiation oncology· PUBMED
Publikáció
Investigating the Link Between Specific Signaling Molecules (CCL5, CCR5, CXCR4, BMPR2) and Cardiac Health Indicators in Rheumatoid Arthritis Individuals: A Cross-Sectional Study.
2026. szept. 11.· Health science reports· PUBMED
Publikáció
CXCR4-directed liposomal co-delivery of cytarabine and AMD3100 for redox-associated chemosensitization in acute myeloid leukemia.
2026. szept. 10.· Colloids and surfaces. B, Biointerfaces· PUBMED
Publikáció
CXCR4+ circulating tumor cells (CTCs) accumulate in subcutaneous, immune suppressive, CXCL12-loaded-hydrogel.
2026. szept. 4.· Materials today. Bio· PUBMED
Publikáció
CXCR4-centred signalling network rewiring distinguishes primary and metastatic prostate cancer: A systems-level digital twin framework.
2026. szept. 3.· European journal of cell biology· PUBMED
Publikáció
Spatial dissection of antibody-drug conjugate/radiopharmaceutical therapy targets defines heterogeneous expression landscapes and therapeutic implications in rhabdoid tumors.
2026. szept. 1.· Neuro-oncology· PUBMED
Publikáció
Design, Preclinical Evaluation, and Clinical Translation of [68Ga]Ga/[177Lu]Lu-JH120061, a Novel Radiopharmaceutical Targeting CXCR4.
2026. szept. 1.· Clinical cancer research : an official journal of the American Association for Cancer Research· PUBMED