FAK

Betegségek

• Ovarian cancer5 vizsgálat
• Pancreatic cancer3 vizsgálat
• Cervical cancer1 vizsgálat
• Childhood cancers1 vizsgálat
• Colorectal cancer1 vizsgálat
• Lung cancer1 vizsgálat
• Neuroblastoma1 vizsgálat

Az elmúlt 24 hónap

Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.

VizsgálatokPublikációkPreprintekPályázatok

• Publikáció

  A Retinal Matrix Stiffening Model Reveals FAK-Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization.

  2026. nov. 2.· Advanced materials (Deerfield Beach, Fla.)· PUBMED

• Publikáció

  Modulation of the FAK-Src Signalling Axis by Oncoviruses: Molecular Mechanisms, Functional Consequences, and Therapeutic Opportunities.

  2026. nov. 1.· Reviews in medical virology· PUBMED

• Publikáció

  Correction: Strategic selection of MDM2 inhibitors enhances the efficacy of FAK inhibition in mesothelioma based on TP53 genotype.

  2026. okt. 26.· PloS one· PUBMED

• Publikáció

  Zyxin protects against hypertensive nephropathy by restraining FAK/Skp2-CDK8/YAP signaling in tubular epithelial cells.

  2026. okt. 17.· Inflammation research : official journal of the European Histamine Research Society ... [et al.]· PUBMED

• Publikáció

  Irisin promotes lipid clearance through the CD81-integrin-FAK axis in steatotic hepatocytes.

  2026. okt. 17.· Journal of physiology and biochemistry· PUBMED

• Publikáció

  A marine-derived sesterterpenoid inhibits migration and invasion of triple-negative breast cancer cells by suppressing the FAK signaling pathway.

  2026. okt. 15.· Frontiers in cell and developmental biology· PUBMED

• Publikáció

  PINK1 promotes the progression of lung squamous cell carcinoma through the FAK/AKT/RhoA/vinculin pathway.

  2026. okt. 2.· Oncology reports· PUBMED

• Publikáció

  FAK inhibitor and RAF/MEK clamp avutometinib enhance KRAS G12C inhibitor efficacy in preclinical models of non-small cell lung cancer.

  2026. szept. 30.· Science translational medicine· PUBMED

• Publikáció

  Progress with FAK inhibitors in the patent literature (2020-present).

  2026. szept. 20.· Expert opinion on therapeutic patents· PUBMED

• Publikáció

  Tumor FAK supports fibrillar collagen expression in ovarian cancer ascites.

  2026. szept. 17.· Matrix biology : journal of the International Society for Matrix Biology· PUBMED

• Publikáció

  β-Myrcene alleviates atopic dermatitis-like inflammation and is associated with ECM-FAK/Src-YAP signaling during epidermal barrier repair.

  2026. szept. 16.· European journal of pharmacology· PUBMED

• Publikáció

  Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation.

  2026. szept. 14.· Molecular oncology· PUBMED

• Publikáció

  Narciclasine reduces proliferation and migration of neuroblastoma cells and decreases FAK/PI3K pathway activation.

  2026. aug. 29.· Medical oncology (Northwood, London, England)· PUBMED

• Preprint

  Loss of endothelial cell FAK represses cisplatin-induced vascular senescence in distal niches to reduce lung metastatic burden.

  2026. aug. 25.· Research square· PUBMED

• Publikáció

  Neutrophil Extracellular Trap-Derived DNA Activates the ITGB1/FAK Pathway to Promote Lung Adenocarcinoma Metastasis.

  2026. aug. 24.· Cancer research· PUBMED

• Publikáció

  Acid-activated Fe-doped layered double hydroxides coupling FAK blockade and chemodynamic therapy for triple-negative breast cancer.

  2026. aug. 20.· Biomaterials advances· PUBMED

• Publikáció

  ONC201 enhances the radiosensitivity of small-cell lung cancer via inhibition of the FAK signaling pathway.

  2026. aug. 14.· iScience· PUBMED

• Publikáció

  2-Ethylhexyl diphenyl phosphate exposure is associated with poorer overall survival in advanced high-grade serous ovarian cancer: Integrated epidemiological and experimental evidence implicating the ITGB1-FAK-AKT axis.

  2026. aug. 11.· Ecotoxicology and environmental safety· PUBMED

• Publikáció

  Combined FAK and MEK inhibition suppresses chromosome 8 gain malignant peripheral nerve sheath tumors.

  2026. aug. 11.· The Journal of clinical investigation· PUBMED

• Publikáció

  Editor's Note: FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells.

  2026. aug. 5.· Carcinogenesis· PUBMED

• Publikáció

  Scutellarin alleviates obesity-induced renal fibrosis by regulating ITGA9 to suppress FAK/PI3K/AKT signaling.

  2026. aug. 3.· Phytomedicine : international journal of phytotherapy and phytopharmacology· PUBMED

• Publikáció

  RETRACTION: Fibronectin Promotes Migration and Invasion of Ovarian Cancer Cells through Up-Regulation of FAK-PI3K/Akt Pathway.

  2026. aug. 1.· Cell biology international· PUBMED

• Publikáció

  Novel androgen receptor N-terminal mutation drives gastric cancer metastasis via YWHAZ-mediated FAK pathway activation.

  2026. júl. 30.· Journal of translational medicine· PUBMED

• Publikáció

  Cuproplasia-associated LOXL2 cooperates with Helicobacter pylori infection to promote gastric cancer progression via the FAK/Src signaling axis.

  2026. júl. 24.· Journal of gastrointestinal oncology· PUBMED

• Publikáció

  Laminin γ2-ITGβ1-PD-L1 axis mediates gastric cancer cell heterogeneity in response to GCMSCs via FAK/YAP pathway.

  2026. júl. 23.· Cellular signalling· PUBMED

• Publikáció

  Syntaphilin Regulates Epithelial-Mesenchymal Transition and Metastasis in Gastric Cancer via the FAK/NF-κB/MMP-9 Signaling Pathway.

  2026. júl. 23.· International journal of molecular sciences· PUBMED

• Publikáció

  N6-methyladenosine-mediated upregulation of PAICS promotes lung-adenocarcinoma metastasis via the integrin-FAK signaling.

  2026. júl. 23.· Oncogene· PUBMED

• Publikáció

  WLJP-025p, a pectic polysaccharide from Lonicera japonica Thunb., suppresses proliferation and cellular respiration in IHH-4 thyroid cancer cells through a Gal-3-associated FAK/SRC signaling pathway.

  2026. júl. 22.· International journal of biological macromolecules· PUBMED

• Publikáció

  Scaffold hopping-directed design and discovery of N1-substituted aminopyrimidine-indole derivatives as FAK inhibitors with anti-pancreatic cancer activity.

  2026. júl. 17.· Bioorganic & medicinal chemistry· PUBMED

• Preprint

  Induced ERBB response and standing FAK dependency nominate separable KRAS-combination hypotheses in pancreatic cancer.

  2026. júl. 10.· bioRxiv : the preprint server for biology· PUBMED

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