Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
Anticancer activity of sodium propionate in hepatocellular carcinoma cells via downregulation of HDAC2 and HDAC6.
2026. nov. 6.· Journal of computer-aided molecular design· PUBMED
Publikáció
Salidroside alleviates MPP+-induced injury and mitochondrial fission in PC12 cells by mediating the HDAC6/MST1/MIEF1 axis.
2026. nov. 6.· The International journal of neuroscience· PUBMED
Publikáció
Integrative miRNA-multi-omics analysis of brain-metastasis predisposition in non-small cell lung cancer prioritizes HDAC inhibitors and anti-miR-330-3p as hypothesis-generating therapeutic candidates.
2026. nov. 5.· Functional & integrative genomics· PUBMED
Publikáció
HDAC inhibition drives NOX5-dependent oxidative stress and sensitizes uveal melanoma cells to SOD1 inhibition.
2026. nov. 2.· The Journal of biological chemistry· PUBMED
Publikáció
FAM60A Regulates SIN3A-HDAC Complex Activity to Induce G1/S Phase Arrest and Promote Differentiation of Low-Grade Glioma.
2026. nov. 1.· Biology of the cell· PUBMED
Publikáció
Recent Progress in HDAC-Based Dual-Target Inhibitors for Colorectal Cancer.
2026. nov. 1.· Drug development research· PUBMED
Publikáció
New sulfonamide derivatives as HDAC inhibitors and apoptosis inducers: design, synthesis, in silico study and anticancer evaluation.
2026. okt. 27.· RSC advances· PUBMED
Publikáció
Structure-Based Design of HDAC6 Inhibitors Targeting the L2 Pocket: Modulating Autophagy and Liquid-Liquid Phase Separation in Lung Cancer.
2026. okt. 22.· Journal of medicinal chemistry· PUBMED
Publikáció
Design, Synthesis, Molecular Docking, and Anticancer Activity Evaluation of Chalcone Derivatives as HDAC6 Inhibitors.
2026. okt. 21.· Die Pharmazie· PUBMED
Publikáció
Differential Regulation of Cholesterol-Related Gene Expression by HDAC Inhibition in Neuron-Enriched and Glia-Enriched Rat Primary Cultures.
2026. okt. 17.· International journal of molecular sciences· PUBMED
Publikáció
Editor's Note: Ubiquitin Proteasome System Stress Underlies Synergistic Killing of Ovarian Cancer Cells by Bortezomib and a Novel HDAC6 Inhibitor.
2026. okt. 15.· Clinical cancer research : an official journal of the American Association for Cancer Research· PUBMED
Publikáció
Disabling COMPASS Promoter Licensing Shifts HDAC-Inhibited Gastric Cancer Toward Sustained Transcriptional Suppression During Recovery.
2026. okt. 15.· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publikáció
Restoring Neural Homeostasis via Class II HDAC Modulation: Mechanistic Insights and Therapeutic Opportunities.
2026. okt. 15.· Molecular neurobiology· PUBMED
Publikáció
Discovery of a Novel HDAC1 Inhibitor to Potentiate Ferroptosis with Arachidonic Acid in ESCC.
2026. okt. 8.· Journal of medicinal chemistry· PUBMED
Preprint
Combined HDAC and ATM inhibition with radiation in preclinical glioblastoma models.
2026. okt. 7.· bioRxiv : the preprint server for biology· PUBMED
Publikáció
A Patient-Derived Screen Identifies HDAC Inhibitors as Enhancers of Phagocytosis and Potent Immunotherapy Partners.
2026. okt. 5.· Cancer immunology research· PUBMED
Publikáció
Targeting the DNHD1‑HDAC6 axis inactivates prostate cancer cell aggressiveness in vitro, suggesting potential therapeutic vulnerability.
2026. okt. 2.· Oncology reports· PUBMED
Publikáció
HDAC Inhibition Unlocks Tumor Plasticity and Enhances Immunotherapy Response in Myc-Driven Small Cell Lung Cancer.
2026. okt. 2.· Molecular cancer therapeutics· PUBMED
Publikáció
Corrigendum to "Effect and mechanism of novel HDAC inhibitor ZDLT-1 in colorectal cancer by regulating apoptosis and inflammation" [Int. Immunopharmacol. 143 (2024) 113333].
2026. szept. 28.· International immunopharmacology· PUBMED
Publikáció
Substituted methyl acridone-carboxylate derivatives as CD1/CD2 dual-targeting HDAC6 inhibitors to ameliorate the pathological phenotype of Alzheimer's disease.
2026. szept. 19.· European journal of medicinal chemistry· PUBMED
Publikáció
Novel Class I HDAC Inhibitors Sensitize Ovarian Cancer Cells for Cisplatin and Niraparib via an HDAC3-SLFN11 Axis.
2026. szept. 18.· ACS chemical biology· PUBMED
Publikáció
Astragaloside IV alleviates heart failure by restoring gut microbiota-derived short-chain fatty acids and suppressing HDAC1/2/3.
2026. szept. 16.· Biochemical and biophysical research communications· PUBMED
Publikáció
Rapid Two-Step Multicomponent Synthesis and Structure-degradation Relationships of Selective HDAC6 PROTAC Degraders.
2026. szept. 10.· Journal of medicinal chemistry· PUBMED
Publikáció
Gut microbiota as a modulator of HDAC: insights into Alzheimer's disease treatment.
2026. szept. 9.· Pharmacological reports : PR· PUBMED
Publikáció
Design, synthesis, and screening of novel thienopyrimidine derivatives as PI3K/HDAC dual inhibitors against cervical cancer cells.
2026. szept. 8.· European journal of medicinal chemistry· PUBMED
Publikáció
USP19 facilitates CSE-induced cell damage and ferroptosis in chronic obstructive pulmonary disease by deubiquitinating HDAC6 to drive PRDX6 deacetylation.
2026. szept. 8.· Immunologic research· PUBMED
Publikáció
Imidazo[1,2-a]pyridine-based HDAC6 inhibitor a17 for the treatment of Alzheimer's disease.
2026. szept. 5.· European journal of pharmacology· PUBMED
Publikáció
Machine Learning and Molecular Modeling Reveal HDAC6 as a Key Target of Tanshinone IIA in Multiple Myeloma.
2026. szept. 3.· The journal of physical chemistry. B· PUBMED
Publikáció
HDAC1 lactylation drives diabetic retinopathy by orchestrating a pro-angiogenic epigenetic program.
2026. szept. 2.· Cell reports· PUBMED
Publikáció
Sotagliflozin, a Dual SGLT1/2 Inhibitor, Modulates DNMT1 and Class I/II HDAC Expression in Association With Anticancer Effects in Breast and Lung Cancer Cells.
2026. szept. 1.· Cell biology international· PUBMED