Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
IDO1 methylation by EZH2 confers resistance to its targeted therapy in colorectal cancer through tryptophan-kynurenine metabolic rewiring.
2026. nov. 5.· Cell reports· PUBMED
Publikáció
ShenqiYichang decoction enhances colorectal cancer immune efficacy via IDO1 mediated reduction of Treg infiltration.
2026. okt. 14.· Journal of ethnopharmacology· PUBMED
Publikáció
IDO1 integrates gut microbiota-derived SCFAs signals and host WNT/TGF-β pathways to mediate the anti-colorectal cancer effects of licorice flavonoids.
2026. szept. 23.· Pharmacological research· PUBMED
Publikáció
CPT1A-mediated IDO1 succinylation shapes EGFRvIII-driven resistance to tumor electric field therapy in glioblastoma.
2026. szept. 23.· Nature communications· PUBMED
Publikáció
Phase 1 study of KHK2455, a long-acting, potent and selective IDO1 inhibitor, in combination with avelumab in patients with locally advanced or metastatic urothelial carcinoma.
2026. szept. 21.· Journal for immunotherapy of cancer· PUBMED
Publikáció
Design and Computational Evaluation of Isatin Derivatives as Dual MAO-A/IDO1 Inhibitors: Molecular Docking and Molecular Dynamics Insights.
2026. szept. 21.· Current medicinal chemistry· PUBMED
Publikáció
Astaxanthin alleviates Parkinson's disease via dual regulation of tryptophan metabolism: central STAT3/IDO1 inhibition and gut microbiota remodeling.
2026. szept. 14.· Food research international (Ottawa, Ont.)· PUBMED
Publikáció
[Mechanistic study on Kaixin Powder ameliorating chronic stress-induced CD8~+T cell exhaustion and delaying lung adenocarcinoma progression by modulating IDO1/Kyn/Ahr axis].
2026. szept. 1.· Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica· PUBMED
Publikáció
Design, synthesis, antitumor estimation, and molecular docking of new imidazothiazolediones as potential dual EGFR and IDO1 inhibitors and apoptosis stimulators.
2026. aug. 27.· Bioorganic & medicinal chemistry· PUBMED
Publikáció
Tanshinone IIA restores CD8+ T-cell immunity in TNBC by suppressing the IDO1-kynurenine axis.
2026. aug. 25.· Frontiers in pharmacology· PUBMED
Publikáció
Phase I Evaluation of Patients with Newly Diagnosed Glioblastoma Treated with Radiation, Nivolumab, and IDO1 Enzyme Inhibitor BMS-986205.
2026. aug. 14.· Clinical cancer research : an official journal of the American Association for Cancer Research· PUBMED
Publikáció
IDO1 Silencing Enhances Cisplatin Sensitivity in Gastric Cancer Cells via Modulation of Apoptosis and Oxidative Stress.
2026. júl. 27.· Current issues in molecular biology· PUBMED
Publikáció
Targeting the AHR-IDO1-kynurenine pathway in TREM2+ macrophages restores antitumor immunity in thyroid cancer.
2026. júl. 21.· Frontiers in immunology· PUBMED
Publikáció
Split immunomodulatory impact of leptin on human myeloid cells: key role of IDO1 in counteracting the immunostimulatory effect of leptin.
2026. júl. 10.· Journal of immunology (Baltimore, Md. : 1950)· PUBMED
Publikáció
Immune evasion in locally advanced mismatch repair-deficient microsatellite instability-high colorectal cancer: Reduced T-cell infiltration and upregulation of epithelial IDO1 expression.
2026. júl. 9.· Oncoimmunology· PUBMED
Publikáció
Corrigendum to "Erzhi pill enhances methotrexate efficacy in rheumatoid arthritis bone homeostasis via activation of the IDO1-KYN-AhR pathway" [Phytomedicine 157 (2026) 158290].
2026. jún. 26.· Phytomedicine : international journal of phytotherapy and phytopharmacology· PUBMED
Publikáció
Serum IDO1 and β-catenin levels in patients with multiple sclerosis with and without atherosclerosis: A case-control study.
2026. jún. 24.· Journal of neuroimmunology· PUBMED
Publikáció
20(S/R)-Ginsenoside Rh1 Alleviates AOM/DSS-Induced Colorectal Cancer: Gut-Microbiota Modulation and Tryptophan-Metabolism-Mediated AhR/PXR Activation and IDO1.
2026. jún. 17.· International journal of molecular sciences· PUBMED
Publikáció
Cancer IDO1-Mediated Tryptophan-Kynurenine Metabolic Reprogramming to Drive Skeletal Muscle Atrophy and Cachexia Acceleration.
2026. jún. 1.· Journal of cachexia, sarcopenia and muscle· PUBMED
Publikáció
Indoleamine 2,3-dioxygenase 1 (IDO1) promoted the activation of inflammatory response in the brain tissue of Alzheimer's disease mice by regulating NF-κB pathway.
2026. máj. 19.· Neuroscience letters· PUBMED
Publikáció
Erzhi pill enhances methotrexate efficacy in rheumatoid arthritis bone homeostasis via activation of the IDO1-KYN-AhR pathway.
2026. máj. 14.· Phytomedicine : international journal of phytotherapy and phytopharmacology· PUBMED
Publikáció
Clinical Significance of Serum CCR2 and IDO1 in Diabetic Peripheral Neuropathy.
2026. márc. 25.· Diabetes, metabolic syndrome and obesity : targets and therapy· PUBMED
Publikáció
Increased LAG-3, TIM-3, and IDO1 Expression Is Associated With Oral Squamous Cell Carcinoma in Never Smokers and Never Drinkers.
2026. márc. 19.· Oral diseases· PUBMED
Publikáció
Machine learning-driven drug discovery for the management of TNBC: focus on IDO1 and TDO targets.
2026. márc. 17.· SAR and QSAR in environmental research· PUBMED
Publikáció
Nexus of IDO1/Kynurenine Pathway to T-Cell Exhaustion: Hypoxia-Induced Tryptophan Metabolism in Glioblastoma.
2026. márc. 10.· Metabolites· PUBMED
Publikáció
The IDO1/AhR-HIF-1α metabolic axis: ARNT competition as a central antagonistic switch in autoimmune pathogenesis.
2026. márc. 6.· Frontiers in immunology· PUBMED
Publikáció
Differential Effects of Saturated and Unsaturated Fatty Acids on Colorectal Cancer via IDO1 Signaling.
2026. márc. 1.· Cancer medicine· PUBMED
Publikáció
Design, synthesis and anti-Parkinson's disease bioactivity evaluation of isoquinoline derivatives as potent IDO1/TDO dual inhibitors.
2026. febr. 22.· Bioorganic & medicinal chemistry letters· PUBMED
Publikáció
Galangin-loaded biomimetic dendritic cells membrane nanovaccine reprograms the ovarian cancer microenvironment via Stat3/IDO1/AhR axis to boost immunotherapy.
2026. febr. 10.· Materials today. Bio· PUBMED
Publikáció
Estrogen regulates cognitive function in APP/PS1 female mice via modulation of IDO1-mediated Trp/Kyn metabolism through ERβ.
2026. febr. 9.· Hormones and behavior· PUBMED