Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
β-elemene suppressed EMT via IGF1R inhibition in osimertinib treated AXL low-expressing EGFR mutant non-small cell lung cancer.
2026. nov. 2.· European journal of pharmacology· PUBMED
Publikáció
Experimental high blood glucose metabolically rejuvenates CD8+ T cells for improved control of tumor growth through an IGF1-IGF1R axis.
2026. okt. 1.· Journal of immunology (Baltimore, Md. : 1950)· PUBMED
Publikáció
IGF1R Induces ROS Formation in Mitochondria via MICU1 Leads to the Enzalutamide Resistance in Prostate Cancer.
2026. okt. 1.· Journal of cellular and molecular medicine· PUBMED
Publikáció
Hypertension with defective IGF1R-PI3K signalling may trigger atrial cardiomyopathy, atrial fibrillation, and stroke.
2026. szept. 22.· European heart journal· PUBMED
Publikáció
IGF1-IGF1R signaling in tumor-associated macrophages regulates extracellular matrix organization in BRAF inhibitor-targeted melanoma.
2026. aug. 31.· Molecular and cellular biochemistry· PUBMED
Publikáció
PD-L1 upregulated by IGF1R via the PI3K/AKT/NF-κB axis induces sorafenib resistance in hepatocellular carcinoma.
2026. aug. 21.· Molecular immunology· PUBMED
Publikáció
Delayed growth of SK-ES-1 Ewing sarcoma tumor xenografts is associated with reduced Trk and IGF1R pathway markers.
2026. aug. 7.· Oncotarget· PUBMED
Publikáció
Growth factor receptors IGF-1R and VEGFR2 are associated with the prognosis of patients with esophageal cancer after esophagectomy.
2026. júl. 27.· Open life sciences· PUBMED
Publikáció
Overcoming IGF1R-mediated resistance to oncolytic HSV1 and radiotherapy via triple combination therapy.
2026. júl. 17.· Cell death & disease· PUBMED
Publikáció
TMEM216 inhibits breast cancer lung metastasis by modulating IGF1R-IRS4 signaling pathway.
2026. júl. 1.· Nature communications· PUBMED
Publikáció
MALAT1 promotes autophagy via the mir-28-5p/IGF1R axis in nasopharyngeal carcinoma.
2026. jún. 26.· Medical oncology (Northwood, London, England)· PUBMED
Publikáció
Erratum: [Corrigendum] Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF-1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase-3 signaling pathway in small cell lung cancer.
2026. jún. 22.· Oncology letters· PUBMED
Publikáció
Exosomal miRNA-714 derived from adipose tissue macrophages regulates adipocyte glucose and lipid metabolism via IGF1R targeting.
2026. jún. 22.· Nutrition & metabolism· PUBMED
Publikáció
[The Effect of MiR-100-5p on the Biological Behaviors of Pediatric Acute Myeloid Leukemia Cells by Targeting IGF1R].
2026. jún. 1.· Zhongguo shi yan xue ye xue za zhi· PUBMED
Publikáció
Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease.
2026. máj. 23.· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publikáció
Insulin-like Growth Factor 1 Ameliorates Intestinal Barrier Dysfunction in MASLD via IGF-1R/PI3K/AKT Signaling.
2026. máj. 22.· Nutrients· PUBMED
Publikáció
Loss of IGF-1R impairs DNA-PKcs recruitment to chromatin leading to defective end-joining.
2026. máj. 7.· Molecular oncology· PUBMED
Publikáció
miR-449b-5p from adipose-derived mesenchymal stem cell-derived exosomes targets IGF1R to alleviate airway inflammation and improve airway smooth muscle cell dysfunction in children with asthma.
2026. ápr. 15.· Journal of immunology (Baltimore, Md. : 1950)· PUBMED
Publikáció
Nuclear Translocation of IGF1R Induces Cell Cycle Re-entry via Cyclin D1 Regulation in an Aβ-Driven Alzheimer's Disease Model.
2026. ápr. 15.· Molecular neurobiology· PUBMED
Publikáció
IGF1/IGF-1R promotes hepatocellular carcinoma progression by activating the Akt/GSK-3β pathway.
2026. ápr. 9.· PloS one· PUBMED
Publikáció
Tumor-specific lncRNA IGF1R-AS1 trans-regulates chromatin interactions associated with oncogenic MYC signaling.
2026. márc. 19.· Nature communications· PUBMED
Publikáció
Network analysis-guided drug repurposing: IGF1R as a novel melanoma target and therapeutic potential of dapagliflozin.
2026. márc. 17.· Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences· PUBMED
Publikáció
Myrtenol from Lavender Essential Oil Possesses Neuroprotective Effects and Promotes Neurite Outgrowth by Potentially Targeting TrkA and IGF-1R in PC12 Cells.
2026. márc. 12.· International journal of molecular sciences· PUBMED
Publikáció
Apoptosis induction and migration suppression through regulation of IGF-1R/FoxO signaling pathways in Panc1 pancreatic cancer cells by hAMSCs secretome: An in vitro cell-based therapy.
2026. márc. 10.· Cancer treatment and research communications· PUBMED
Publikáció
Small-nucleolar RNA host gene3 (SNHG3) and leukemia-associated non-coding IGF1R activator RNA 1 (LUNAR1) correlated with CRC patients' clinical features: a step-toward ncRNA-precision.
2026. febr. 26.· Scientific reports· PUBMED
Publikáció
MUC15 loss promotes perineural invasion in pancreatic cancer by activating the IGF1R/STAT3/NGF pathway.
2026. febr. 23.· Cancer letters· PUBMED
Publikáció
HOTAIR promotes the progression of B-cell acute lymphoblastic leukemia by regulating the miR-326/IGF-1R axis and activating the PI3K/AKT signaling pathway.
2026. febr. 16.· Hematology (Amsterdam, Netherlands)· PUBMED
Publikáció
Dual targeting of IGF-1R and K-RAS with natural phytochemicals for lung cancer therapy: an in-silico study.
2026. febr. 10.· Journal, genetic engineering & biotechnology· PUBMED
Publikáció
Therapeutic effects of IGF-2 on NMOSD by inhibiting astrocyte apoptosis through modulation of the IGF-1R/PI3K/AKT signaling pathway.
2026. jan. 27.· Scientific reports· PUBMED
Publikáció
Styrylquinoline Derivatives as IGF1R Inhibitors.
2026. jan. 16.· ACS medicinal chemistry letters· PUBMED