Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
Astragaloside IV ameliorates combined allergic rhinitis and asthma syndrome by inhibiting the activation of the STAT6/GATA3/IL-4 and PI3K/AKT/NF-κB signaling pathways.
2026. okt. 29.· Naunyn-Schmiedeberg's archives of pharmacology· PUBMED
Publikáció
Mast Cell-Derived IL-4 Induces Pathogenic Cardiac Fibroblasts in Heart Failure.
2026. okt. 5.· Circulation· PUBMED
Publikáció
Neonatal IL-4 and IL-5 signaling drives long-term inflammation after early-life allergen exposure in a mouse model of allergic sensitization.
2026. okt. 2.· Frontiers in immunology· PUBMED
Publikáció
Evidence that IL-4/IL-13-Responsive IGFLs Promote Allergic Skin Inflammation.
2026. szept. 30.· The Journal of investigative dermatology· PUBMED
Publikáció
House Dust Mite Induces Distinct Cellular and Extracellular Vesicle-Associated miRNA Signatures in BEAS-2B Cells: Targeted Analysis of IL-4 Responses.
2026. szept. 24.· Cells· PUBMED
Publikáció
Response to "Route of IL-4 administration in Li et al.: an inconsistency between the methods and Section 4.4".
2026. szept. 20.· Brain, behavior, and immunity· PUBMED
Publikáció
Efficacy of probiotics combined with tacrolimus ointment in children with atopic dermatitis and its effects on serum IgE, IL-4, and LTB4: A single-center retrospective cohort study.
2026. szept. 18.· Medicine· PUBMED
Publikáció
Persistent Patch Test Reactivity to Compositae Mix and Sesquiterpene Lactone Mix During Anti-IL-4/IL-13 Therapy in Two Cases.
2026. aug. 28.· Contact dermatitis· PUBMED
Vizsgálat
Dupilumab in Major Depressive Disorder
2026. aug. 27.· PHASE2 · RECRUITING· CTGOV
Publikáció
High Frequency of Circulating IL-4R+SELL+ Naïve B Cells Is Associated with Functional Cure in Chronic Hepatitis B Patients Receiving Antiviral Treatment.
2026. aug. 26.· Journal of clinical and translational hepatology· PUBMED
Publikáció
CGRP receptor antagonism impairs microglial anti-inflammatory function: IL-4 supplementation as a compensatory strategy for migraine.
2026. aug. 25.· Brain, behavior, and immunity· PUBMED
Publikáció
Case Report: Effective IL-4/IL-13 axis suppression and resolution of severe atopic dermatitis by dupilumab monotherapy in a patient with IPEX syndrome.
2026. aug. 17.· Frontiers in immunology· PUBMED
Publikáció
IL-4Rα antagonist (Stapokibart) in refractory palmoplantar pustulosis: a case report and literature review of Th2-targeted therapies.
2026. aug. 13.· Frontiers in immunology· PUBMED
Publikáció
Nasal Lavage IL-4 and IL-13 in Cystic Fibrosis-Related Chronic Rhinosinusitis: Associations With Disease Severity and Potential Implications for Targeted Therapies.
2026. aug. 13.· International forum of allergy & rhinology· PUBMED
Publikáció
Stapokibart (CM310) in Atopic Dermatitis: A Narrative Review of a Next-Generation IL-4Rα Antagonist.
2026. júl. 31.· Dermatology practical & conceptual· PUBMED
Publikáció
[Mechanism study on electroacupuncture regulating IL-4/JAK1/STAT6 signaling pathway to promote M2 macrophage polarization and improve intestinal mucosal barrier injury in mice with ulcerative colitis].
2026. júl. 25.· Zhen ci yan jiu = Acupuncture research· PUBMED
Publikáció
Comment on 'Should Paradoxical Psoriasis Trigger Rheumatological Surveillance During IL-4/IL-13 Blockade?'.
2026. júl. 24.· Clinical and experimental dermatology· PUBMED
Publikáció
Monoclonal antibodies targeting IL-5/5R or IL-4/13 pathways in eosinophilic myocarditis: a single-centre experience and systematic literature review.
2026. júl. 14.· European heart journal. Cardiovascular pharmacotherapy· PUBMED
Publikáció
The potential of targeted IL-4 therapy for the comorbidity of atopic dermatitis and attention-deficit/hyperactivity disorder in children via the skin-brain axis.
2026. júl. 10.· Frontiers in allergy· PUBMED
Publikáció
Elevated IL-4 and IL-13 Expression in Hailey-Hailey Disease: Evidence for Th2-Mediated Pathogenesis and Targeted Treatment.
2026. júl. 6.· Journal of cutaneous pathology· PUBMED
Publikáció
Indole-3-carbinol attenuates DNCB-induced atopic dermatitis in mice by reducing inflammation and IL-4/IL-13 expression.
2026. júl. 2.· Biomolecules & biomedicine· PUBMED
Publikáció
Comment on: Bronchodilator response is linked with uncontrolled moderate-to-severe childhood asthma and elevated IL-4 and IL-13.
2026. júl. 1.· Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology· PUBMED
Publikáció
A novel JAK1 mutation identified in a patient with severe atopic dermatitis phenotype: Mechanistic insights and IL-4Rα targeted therapy.
2026. jún. 30.· Clinical immunology (Orlando, Fla.)· PUBMED
Publikáció
Efficacy and Safety of IL-4Rα and IL-5/IL-5R Targeted Biologic Therapies in Type 2 Inflammatory Airway Diseases: A Systematic Review and Meta-Analysis.
2026. jún. 26.· Journal of clinical medicine· PUBMED
Publikáció
IL-4/IL-13-Driven Dysregulation of Epidermal Lipid Metabolism in Atopic Dermatitis: An Immunometabolic Link Between Type 2 Inflammation and Barrier Dysfunction.
2026. jún. 22.· Cells· PUBMED
Publikáció
IL-4 in Alzheimer's Disease-Mechanisms and Therapeutic Potential.
2026. jún. 20.· Molecular neurobiology· PUBMED
Publikáció
High-dimensional single-cell mass cytometry analysis of IL-4 treated human macrophages reveals heterogeneity and a CD206high anticolitic subset.
2026. jún. 8.· Journal of leukocyte biology· PUBMED
Publikáció
Bronchodilator response is linked with uncontrolled moderate-to-severe childhood asthma and elevated IL-4 and IL-13.
2026. jún. 1.· Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology· PUBMED
Publikáció
Dupilumab attenuate IL-4 and IL-13 synergistic effect on airway remodeling in asthma via blocking IL-4Rα/STAT6 axis.
2026. máj. 30.· Scientific reports· PUBMED
Publikáció
Phase Ib/II Study of Preliminary Efficacy, Safety and Pharmacodynamics of MG-K10, a Humanised Monoclonal Antibody Targeting IL-4Rα, in Adult Chinese Patients With Asthma.
2026. máj. 29.· Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology· PUBMED