Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Vizsgálat
Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)
2027. febr. 1.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Vizsgálat
Mirdametinib to Reduce the Size of Large/Giant Congenital Melanocytic Nevi in Children, Adolescents and Young Adults
2027. jan. 4.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publikáció
Britanin improved high-fat diet-induced obesity by regulating the MAPK signaling pathway.
2026. dec. 1.· Pakistan journal of pharmaceutical sciences· PUBMED
Publikáció
Combined casein kinase II and MAPK signalling inhibition as a therapeutic strategy for metastatic colorectal cancer.
2026. nov. 5.· Experimental hematology & oncology· PUBMED
Publikáció
Early-life cigarette smoke exposure predisposes to COPD by suppressing the HAS2-TGF-B1-MAPK axis in lung fibroblasts.
2026. nov. 3.· Ecotoxicology and environmental safety· PUBMED
Publikáció
Mechanism Investigation of Platycodon grandiflorum Active Ingredients in Regulating Epithelial-Mesenchymal Transition and Airway Remodeling in Asthma via Modulation of the Sirt6/RORγt/IL-17A Axis and IL-17A/MAPK Pathway.
2026. nov. 3.· Journal of ethnopharmacology· PUBMED
Publikáció
JAK1/2 inhibition promotes aggressive cutaneous carcinogenesis through COT kinase-mediated alternative MAPK pathway activation.
2026. nov. 2.· The Journal of clinical investigation· PUBMED
Publikáció
TNFAIP1 Facilitates the Progression of Diabetic Cardiomyopathy Through the p38 MAPK-Mediated ER Stress-Apoptosis Axis.
2026. okt. 31.· FASEB journal : official publication of the Federation of American Societies for Experimental Biology· PUBMED
Publikáció
Ginsenoside Rg6 ameliorates COPD by targeting RAGE to suppress MAPK/NF-κB signaling, thereby preserving alveolar barrier integrity and attenuating EMT.
2026. okt. 29.· Phytomedicine : international journal of phytotherapy and phytopharmacology· PUBMED
Publikáció
Dihydrocaffeic acid alleviates APOE4-associated astrocyte dysfunction and cognitive impairment via LRP1/p38 MAPK signaling.
2026. okt. 28.· Journal of ethnopharmacology· PUBMED
Publikáció
GOLM1 interacts with EGFR and contributes to increased intestinal permeability in ulcerative colitis through p38 MAPK signaling.
2026. okt. 28.· Cellular signalling· PUBMED
Publikáció
Hydroxytyrosol Attenuates Reserpine-Induced Parkinsonism and Hippocampal Damage by Downregulating Pro-inflammatory MAPK/AP-1-Related Gene Expression.
2026. okt. 26.· Neurochemical research· PUBMED
Publikáció
Essential oil from Angelica sinensis Radix attenuates ischemic stroke via the cGMP/PKG/MAPK pathway: insights from network pharmacology and molecular mechanism evaluation.
2026. okt. 23.· Journal of ethnopharmacology· PUBMED
Publikáció
TRIM27 enhances NF-κB/MAPK activation by ubiquitinating and degrading TRAF3 to drive asthma-induced airway inflammation.
2026. okt. 23.· Molecular biology reports· PUBMED
Publikáció
Beyond BRAF V600: emerging MAPK-targeted therapeutic strategies.
2026. okt. 23.· Annals of translational medicine· PUBMED
Publikáció
Inhibition of Bone Morphogenetic Protein 2 Suppresses the Stemness Maintenance of Cancer Stem Cells in Hepatocellular Carcinoma via the MAPK/ERK Pathway [Retraction].
2026. okt. 21.· Cancer management and research· PUBMED
Publikáció
Hesperidin-mediated selenium nanoparticles protect against diabetic cisplatin-induced testicular injury via modulation of Nrf2/Keap1, TLR4/NF-κB/MAPK, and PERK/CHOP Signaling.
2026. okt. 19.· Tissue & cell· PUBMED
Publikáció
Formononetin Protects Osteoblasts Against Oxidative Stress and Attenuates Ovariectomy-Induced Bone Loss in Association with MAPK/AP-1 and NRF2 Signaling.
2026. okt. 19.· Antioxidants (Basel, Switzerland)· PUBMED
Publikáció
From MAPK Reactivation to Response: Clinical Approaches Targeting BRAF/MEK Resistance in Melanoma.
2026. okt. 17.· American journal of clinical dermatology· PUBMED
Publikáció
Ginkgolide B Inhibits Colorectal Cancer Growth via Regulation of the PI3K/AKT/MAPK Pathways: A Comprehensive Analysis Using Network Pharmacology, Molecular Docking, and Verification in Cellular and Animal Models.
2026. okt. 16.· Frontiers in bioscience (Landmark edition)· PUBMED
Publikáció
Aqueous extract of erigeron annuus ameliorates OVA-induced atopic dermatitis-like skin lesions through modulation of Th2-mediated immune responses and MAPK signaling.
2026. okt. 16.· Pharmaceutical biology· PUBMED
Publikáció
Comutation of asxl1 and IDH2R172K enhances leukemogenesis and correlates with epigenetic activation of MAPK and AP-1 in zebrafish.
2026. okt. 13.· Blood advances· PUBMED
Publikáció
Focused Ultrasound-Enhanced Delivery of ED5, a CK1α-Targeting Oleanolic Acid Analogue, Suppresses Glioma Growth via MAPK-ROS-ERS Pathway Modulation.
2026. okt. 12.· Cancer biotherapy & radiopharmaceuticals· PUBMED
Publikáció
Gpr84 activation induces anti-mycobacterial defense in macrophages via MAPK signaling.
2026. okt. 10.· Immunobiology· PUBMED
Publikáció
Inhibition of G6PD-Mediated MAPK Signaling Triggers Mitochondrial Apoptosis and Cell Cycle Arrest in Hepatocellular Carcinoma.
2026. okt. 10.· Frontiers in bioscience (Landmark edition)· PUBMED
Publikáció
Expression of V‑domain Ig suppressor of T cell activation in ovarian cancer and its regulation of follicular regulatory T‑cell function via the AKT/MAPK pathway.
2026. okt. 9.· Oncology reports· PUBMED
Publikáció
Ent-7β-hydroxy-15-oxokaur-16-en-18-yl acetate suppresses RANKL-induced and LPS-enhanced osteoclastogenesis through NF-κB/MAPK signaling with involvement of the ACE-AT1R axis.
2026. okt. 9.· International immunopharmacology· PUBMED
Publikáció
The circMTCL1/miR-145-5p/BMP3 axis suppresses colorectal cancer cell growth by mediating the MAPK signaling pathway.
2026. okt. 8.· Medical oncology (Northwood, London, England)· PUBMED
Publikáció
The Cx43/p38 MAPK/Runx2 signaling pathway as a potential regulatory axis in insufficient osteogenesis associated with osteoporosis.
2026. okt. 8.· Frontiers in endocrinology· PUBMED
Publikáció
Natural (+)-camphor alleviates migraine induced by reserpine with local cerebral vasospasm via inhibiting p38β MAPK/ATF2 pathway.
2026. okt. 8.· Journal of ethnopharmacology· PUBMED