Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
Distinct tau PET dynamics in early versus late age-of-onset Alzheimer's disease.
2026. nov. 4.· Science translational medicine· PUBMED
Publikáció
Integrated manufacturing platform for cortical organoids reveals early phosphatase and prefoldin dysregulation in MAPT V337M neurons.
2026. nov. 3.· NPJ dementia· PUBMED
Publikáció
SSH1 knockdown increases autophagosome formation through ATG9A recruitment and promotes MAPT/tau protein degradation.
2026. nov. 2.· Autophagy· PUBMED
Publikáció
Peripheral α-Synuclein oligomer accumulation in MAPT p.D750V-associated autosomal-dominant parkinsonism: evidence from in vivo skin biopsies.
2026. okt. 31.· Journal of neural transmission (Vienna, Austria : 1996)· PUBMED
Publikáció
Cerebrospinal fluid p62/SQSTM1 is associated with tau pathology, brain structural alterations, and cognitive impairment in adults without dementia.
2026. okt. 30.· Journal of Alzheimer's disease : JAD· PUBMED
Preprint
The human circular Tau 12->7 RNA is translated in mouse neurons and promotes tau aggregation.
2026. okt. 30.· bioRxiv : the preprint server for biology· PUBMED
Preprint
Second-generation tau PET tracer in situ binding assessed with fluorescence imaging.
2026. okt. 27.· Research square· PUBMED
Vizsgálat
A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of NIO752 in Primary Tauopathies
2026. okt. 23.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publikáció
The use of three murine genetic models of Alzheimer's disease reveals efficacy of 4',5,7-trihydroxyisoflavone in alleviating cognitive deficits and reducing levels of amyloid-beta and hyperphosphorylated tau protein.
2026. okt. 22.· Laboratory animal research· PUBMED
Publikáció
BCG vaccination mitigates tau pathology and restores cognitive function in PS19 mice.
2026. okt. 21.· Science advances· PUBMED
Publikáció
A sandwich ECL immunoassay system for tau protein detection using Ru(II)-AuNP signal probes integrated with copper nanoclusters.
2026. okt. 15.· Analytical methods : advancing methods and applications· PUBMED
Publikáció
HuR modulates disease-relevant alternative splicing of MAPT and other Alzheimer's disease-related genes.
2026. okt. 15.· Molecular genetics and genomics : MGG· PUBMED
Publikáció
Early cerebral hypoperfusion promotes spatially biased tau pathology in tau-seeded PS19 mice.
2026. okt. 14.· GeroScience· PUBMED
Publikáció
Perfusion imaging predicts therapeutic cooling response and tracks cis-p-tau pathology in porcine brain injuries.
2026. okt. 8.· Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics· PUBMED
Publikáció
The immunoproteasome in Alzheimer's disease: a dual regulator of tau pathology and microglial senescence.
2026. okt. 3.· Inflammopharmacology· PUBMED
Publikáció
Effects of West Nile Virus on behavioral and cognitive performance, circadian body temperatures, cortical Aβ and p-tau pathology, and immune measures in human apoE and human amyloid precursor protein NL-G-F/human apoE mice.
2026. okt. 2.· Frontiers in immunology· PUBMED
Publikáció
A murine model of amyloid enhanced tauopathy: progressive changes in tau pathology and behavior.
2026. okt. 1.· Alzheimer's & dementia : the journal of the Alzheimer's Association· PUBMED
Publikáció
Pathway-specific polygenic risk scores modify the association between amyloid and tau PET accumulation in patients with Alzheimer's disease.
2026. okt. 1.· Alzheimer's & dementia : the journal of the Alzheimer's Association· PUBMED
Publikáció
Sphingolipid and ceramide associations with tau pathology vary across diverse ethnoracial groups in postmortem brain tissue.
2026. okt. 1.· Alzheimer's & dementia : the journal of the Alzheimer's Association· PUBMED
Publikáció
Chronic mitochondrial DNA depletion alters MAPT splicing and increases tau levels.
2026. szept. 29.· Journal of Alzheimer's disease : JAD· PUBMED
Publikáció
APOE and amyloid-tau pathology in cognitively unimpaired older adults.
2026. szept. 27.· Alzheimer's & dementia (Amsterdam, Netherlands)· PUBMED
Publikáció
CSF neuroinflammatory biomarkers are associated with amyloid-β42/40, tau pathology, and cognitive impairment across the Alzheimer's disease spectrum.
2026. szept. 25.· Immunologic research· PUBMED
Publikáció
Rational design, synthesis, and biological evaluation of indole-piperazine based α-ketoamide derivatives as dual Aβ and tau aggregation modulators for Alzheimer's disease.
2026. szept. 24.· European journal of medicinal chemistry· PUBMED
Publikáció
Ionizing radiation and Alzheimer's disease: epidemiology, mechanisms, and eCIRP-mediated tau pathology.
2026. szept. 22.· Frontiers in immunology· PUBMED
Publikáció
Measuring in-vivo tau pathology in the basal forebrain with PET imaging.
2026. szept. 22.· Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology· PUBMED
Publikáció
Decoding MAPT Exon 10 Mis-Splicing in FTDP-17: From Pathogenic Mechanisms and Experimental Models to Molecular Therapies.
2026. szept. 19.· Genes· PUBMED
Publikáció
Neutrophil-to-lymphocyte ratio predicts early cognitive decline associated with tau pathology in Alzheimer's disease: a longitudinal study of the ADNI cohort.
2026. szept. 16.· Frontiers in aging neuroscience· PUBMED
Publikáció
Targeting C/EBPβ/ Calbindin 1 pathway bolsters the neural resilience to tau pathology and improves tau-impaired episodic memory.
2026. szept. 16.· Molecular psychiatry· PUBMED
Publikáció
Human tau pathology is associated with lonely, nontraveling slow waves linked to memory impairment.
2026. szept. 11.· Nature neuroscience· PUBMED
Publikáció
Nanoconjugation of chalcone derivatives and carbon nitride dots for the inhibition of tau aggregation.
2026. szept. 11.· Colloids and surfaces. B, Biointerfaces· PUBMED