Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
P4HA3 promotes gastric cancer cell proliferation and invasion via the PI3K/AKT/mTOR signaling pathway and regulates glycolytic metabolic reprogramming.
2027. jan. 1.· Pakistan journal of pharmaceutical sciences· PUBMED
Publikáció
N-Benzyl Indole-Benzoxazole Hybrids as Multi-Target Anticancer Agents Modulating mTOR, Apoptosis, and Lipid Dynamics in Breast Cancer.
2026. nov. 6.· Turkish journal of pharmaceutical sciences· PUBMED
Publikáció
RHBDL2 promotes cancer stemness and chemoresistance in triple-negative breast cancer through EGFR/PI3K/AKT/mTOR/c-Myc pathway.
2026. nov. 5.· Oncogene· PUBMED
Publikáció
Niwan Bazhen acupuncture activates CLEC3B-Mediated PI3K/AKT/mTOR signaling pathway to suppress autophagy and exerts neuroprotection against ischemic stroke.
2026. nov. 5.· Neurochemical research· PUBMED
Publikáció
Chongcao Qingfei Capsule alleviates house dust mite-induced allergic airway inflammation by regulating metabolic homeostasis via modulation of the PDE7A-cAMP-AMPK-mTOR axis.
2026. nov. 4.· Journal of ethnopharmacology· PUBMED
Publikáció
Oleanolic Acid and Ursolic Acid Alleviate Obesity-Induced Skeletal Muscle Atrophy via Activation of the IRS/PI3K/AKT/mTOR Signaling Pathway and Attenuation of Oxidative Stress.
2026. nov. 4.· Journal of agricultural and food chemistry· PUBMED
Publikáció
Exogenous tryptophan aggravates experimental lung fibrosis through activation of AKT-mTORC1 pathway.
2026. nov. 3.· PloS one· PUBMED
Publikáció
Characterization of cancer stem-like cells derived from a single 4T1 murine triple-negative breast cancer cell: Involvement of Akt‒mTOR pathway in the proliferation and sphere formation.
2026. nov. 3.· Archives of biochemistry and biophysics· PUBMED
Publikáció
Adaptive induction of NFS1 links mTOR suppression to stemness-associated plasticity in glioblastoma.
2026. nov. 3.· Journal of neuro-oncology· PUBMED
Publikáció
Aspartate inhibits mTORC1 activity and impairs reactivation of HIV-1 provirus.
2026. nov. 2.· Journal of virology· PUBMED
Publikáció
Betaine Attenuates Cuprizone-Induced Cortical Demyelination: The Role of the WNT4/mTOR Signalling Pathway in Regulating Astrogliosis and Synaptic Integrity.
2026. nov. 1.· Journal of biochemical and molecular toxicology· PUBMED
Publikáció
mTOR Inhibition Strategies in Oropharyngeal Carcinoma.
2026. nov. 1.· Anticancer research· PUBMED
Publikáció
Dual mTORC1/2 and Scd1 inhibition uncovers a therapeutic vulnerability in pancreatic cancer.
2026. okt. 31.· Oncogene· PUBMED
Publikáció
Dendrobium officinale extract ameliorates Alzheimer's disease by modulating PI3K-AKT-mTOR pathway and autophagy-related processes: An integrated study combining feature-based molecular networking, network pharmacology and multi-omics.
2026. okt. 31.· Journal of ethnopharmacology· PUBMED
Publikáció
Synergistic effects of docetaxel and anti-PD-L1 therapy on prostate cancer cells: Modulation of apoptosis and PI3K/AKT/mTOR signaling pathway.
2026. okt. 29.· Journal of cancer research and therapeutics· PUBMED
Publikáció
Dietary Leucine Restriction Suppresses Platelet-Driven HCC Growth by Attenuating mTOR Signaling.
2026. okt. 28.· Cancer science· PUBMED
Publikáció
Tectochrysin alleviates idiopathic pulmonary fibrosis via inhibiting PI3K/AKT/mTOR signaling pathway by targeting PI3K p85.
2026. okt. 28.· Pulmonary pharmacology & therapeutics· PUBMED
Publikáció
Relaxin-2 protects synaptic integrity via hippocampal NLRP3-mTOR-autophagy pathways in an age-dependent Alzheimer-like model.
2026. okt. 26.· Acta pharmaceutica (Zagreb, Croatia)· PUBMED
Publikáció
Recombinant spinach ribosome-inactivating protein induces cytotoxicity and alters gene expression associated with PTEN/AKT/mTOR signaling, apoptosis, and stemness in HT29 cells.
2026. okt. 23.· European journal of pharmacology· PUBMED
Publikáció
Corrigendum to "Sishen Wan suppresses colon cancer through dual inhibition of PI3K/AKT/mTOR and STAT3-mitophagy pathways: Network pharmacology and experimental validation" [J Ethnopharmacol, (2026), 360, 121039].
2026. okt. 23.· Journal of ethnopharmacology· PUBMED
Publikáció
P2Y6 receptor activation promotes the migration, invasion and glycogen accumulation of colorectal cancer through AKT/mTOR signaling.
2026. okt. 22.· Tissue & cell· PUBMED
Publikáció
Hyaluronan-Mediated Motility Receptor Potentiates Colorectal Carcinoma Progression Through PI3K/AKT/mTOR Pathway Modulation.
2026. okt. 22.· Asia-Pacific journal of clinical oncology· PUBMED
Publikáció
Licorice flavonoids ameliorate type 2 diabetes mellitus via modulation of the AMPK/mTORC1/AKT signaling network.
2026. okt. 22.· Journal of drug targeting· PUBMED
Publikáció
The potential impact of radiation-synthesized chitosan coated titanium dioxide nanoparticles on hepatocellular carcinoma: Modulation of autophagy via AMPK, mTOR, and ULK-1 pathways in a rat model.
2026. okt. 20.· Bioorganic chemistry· PUBMED
Publikáció
NUAK isoforms promote glucose and glutamine metabolic reprogramming driven colon cancer progression and migration through regulation of AMPK/mTOR signaling.
2026. okt. 20.· Journal of molecular medicine (Berlin, Germany)· PUBMED
Publikáció
The dual role of the PI3K/AKT/mTOR axis in glial cell survival and neuroinflammation.
2026. okt. 17.· Naunyn-Schmiedeberg's archives of pharmacology· PUBMED
Publikáció
SEC31A promotes gastric cancer progression by inducing the PI3K/AKT/mTOR pathway and enhancing the CCL5‑mediated M2 polarization and recruitment of tumor‑associated macrophages.
2026. okt. 16.· Oncology reports· PUBMED
Publikáció
Disporum cantoniense suppresses non‑small cell lung cancer through AMPK/mTOR/ULK1‑mediated autophagy‑dependent apoptosis.
2026. okt. 16.· International journal of oncology· PUBMED
Publikáció
Bisphenol A induces hepatotoxicity via a LAMP3-dependent impairment of mitophagic processing and reduced PI3K-AKT-mTOR signaling.
2026. okt. 15.· Free radical biology & medicine· PUBMED
Publikáció
Retraction: The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human glioblastoma, reduces Akt/mTOR activities, and modulates GSC cell-renewal properties.
2026. okt. 15.· Frontiers in pharmacology· PUBMED