Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Vizsgálat
Combination of Avutometinib and Defactinib for Treatment of Relapsed, Refractory, Metastatic, or Unresectable Malignant Peripheral Nerve Sheath Tumor
2027. jan. 1.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Vizsgálat
Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade Glioma
2027. jan. 1.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publikáció
17q11.2 Duplication (includes NF1 gene): A Scoping Review.
2026. nov. 5.· Genetics in medicine : official journal of the American College of Medical Genetics· PUBMED
Publikáció
Identification of CD74-Positive Antigen-Presenting Glioma Cells in Primary Human Tumors and Murine Models of NF1 High-Grade Glioma.
2026. okt. 2.· Molecular cancer therapeutics· PUBMED
Publikáció
Exceptional and Durable Response to Selpercatinib in a Patient with Apparently RET-Negative, HRAS-, and NF1-Mutated Metastatic Medullary Thyroid Carcinoma.
2026. okt. 1.· Thyroid : official journal of the American Thyroid Association· PUBMED
Vizsgálat
Cognitive Intervention for Children and Adolescents With NF1
2026. szept. 28.· NA · NOT_YET_RECRUITING· CTGOV
Publikáció
Neurofibromatosis 1 (NF1) gene testing reveals rising variant allele fraction as an early warning sign of juvenile myelomonocytic leukemia.
2026. szept. 11.· European journal of medical genetics· PUBMED
Vizsgálat
A study of Mirdametinib in Infants and Toddlers under 24months of age with Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PNs)
2026. szept. 3.· PHASE1 · RECRUITING· CTIS
Publikáció
Single-Cell Analysis Guides Organoid CRISPR Screening to Reveal NF1 as a Gatekeeper of Cervical Squamous Malignant Transformation.
2026. szept. 3.· Cancer research· PUBMED
Publikáció
Colon cancer in a patient with a mosaic monoallelic germline pathogenic NF1 gene variant.
2026. szept. 3.· Exploration of neuroscience· PUBMED
Publikáció
NF1 alterations as potential biomarker in acral melanoma: looking beyond low tumor mutational burden.
2026. aug. 25.· Melanoma research· PUBMED
Vizsgálat
Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas
2026. aug. 4.· PHASE2 · RECRUITING· CTGOV
Vizsgálat
Gait in Young Children With NF1
2026. aug. 1.· NA · NOT_YET_RECRUITING· CTGOV
Publikáció
NF1 Leucine Rich Domain-Derived Extracellular Vesicles Remodel the Glioblastoma Immune Microenvironment via an ADAM17-Associated Inflammatory Program.
2026. aug. 1.· Journal of extracellular vesicles· PUBMED
Publikáció
Spatial proteomic profiling reveals an association between NF1-Ras/Raf/MEK signaling and immune cell infiltration in locally advanced triple-negative breast cancer.
2026. júl. 28.· Translational oncology· PUBMED
Publikáció
Sleep Health and Quality of Life in Children and Adolescents with NF1: A Biopsychosocial Perspective.
2026. júl. 22.· Cancers· PUBMED
Publikáció
Case Report: Schwann cell reprogramming and PDGF-driven nerve hypertrophy in an NF1 patient with CIDP-like autoimmunity.
2026. júl. 17.· Frontiers in immunology· PUBMED
Publikáció
Epilepsy, Cognitive, and Behavioral Outcomes in Neurocutaneous Syndromes: A Comparative Review of NF1, TSC, and Sturge-Weber Syndrome.
2026. júl. 9.· Children (Basel, Switzerland)· PUBMED
Publikáció
Cognitive function in adult NF1 patients without other cognitive disorders: a cross-sectional study.
2026. júl. 3.· Orphanet journal of rare diseases· PUBMED
Publikáció
Durable responses to long-term selumetinib in Chinese pediatric NF1 patients with inoperable plexiform neurofibromas.
2026. jún. 18.· Frontiers in pharmacology· PUBMED
Publikáció
NF1 mutation may be associated with lung-tropic metastasis in cutaneous melanoma: a genomic analysis of 520 patients.
2026. jún. 6.· Clinical & experimental metastasis· PUBMED
Vizsgálat
Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST
2026. jún. 1.· PHASE1_PHASE2 · RECRUITING· CTGOV
Publikáció
NF1 loss in estrogen receptor-positive breast cancer induces osteoclast formation and immunosuppression to promote bone metastasis.
2026. máj. 29.· Cancer letters· PUBMED
Publikáció
Exceptional response to everolimus in an NF1-deficient recurrent endometrioid adenocarcinoma: a case report.
2026. máj. 25.· Frontiers in oncology· PUBMED
Publikáció
Prognostic impact of NF1 mutation in Korean cohort with glioblastoma.
2026. máj. 21.· Frontiers in neurology· PUBMED
Publikáció
Integrative Genomic and Functional Analysis Reveals NF1 Loss as a Modifier of DNA Damage and Replication Stress Responses in Ovarian Cancer.
2026. máj. 18.· Human mutation· PUBMED
Publikáció
Melanoma with Blue Nevus-like Morphology Harboring NRAS and NF1 Mutation.
2026. máj. 17.· Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG· PUBMED
Publikáció
Bridging the Diagnostic Gap in Neurofibromatosis Type 1: When to Consider NF1 cDNA Sequencing.
2026. máj. 13.· Pediatric dermatology· PUBMED
Publikáció
Is cognitive profiling in NF1 still optional? A systematic review of current assessment practices.
2026. ápr. 30.· Frontiers in neurology· PUBMED
Publikáció
Regulation and Implementation of Apoptosis in Melanoma Tumor Cells with BRAF, NRAS, and NF1 Gene Mutations.
2026. ápr. 22.· Current issues in molecular biology· PUBMED