NMDA

Betegségek

• Depression11 vizsgálat
• Schizophrenia9 vizsgálat
• Alzheimer disease5 vizsgálat
• Bipolar disorder2 vizsgálat
• Parkinson disease1 vizsgálat

Az elmúlt 24 hónap

Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.

VizsgálatokPublikációkPreprintekPályázatok

• Vizsgálat

  A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial

  2026. dec. 1.· PHASE2_PHASE3 · RECRUITING· CTGOV

• Publikáció

  The efficacy of NMDA receptor antagonists in neuropsychiatric and non-motor symptoms of Parkinson's disease: a systematic review.

  2026. nov. 2.· Dementia & neuropsychologia· PUBMED

• Publikáció

  Differential NMDA-Evoked Excitatory and Inhibitory Neuronal Responses Under In Vivo and Ex Vivo Conditions in 5xFAD Mice.

  2026. nov. 1.· The European journal of neuroscience· PUBMED

• Publikáció

  Discovery of potent, selective, and orally bioavailable GluN2B-NMDA receptor antagonists for the treatment of depression.

  2026. okt. 29.· European journal of medicinal chemistry· PUBMED

• Publikáció

  ASIC1a as an integrating node in ischemic neurotoxicity: crosstalk with NMDAR and TRPM signaling.

  2026. okt. 20.· Pflugers Archiv : European journal of physiology· PUBMED

• Vizsgálat

  Dissecting Immunological and Autoimmune Mechanisms of Neuropsychiatric Diseases

  2026. okt. 1.· NA · NOT_YET_RECRUITING· CTGOV

• Publikáció

  Embryonic Depletion of D-Aspartate Perturbs NMDA Receptor-Dependent Long-Term Potentiation in the Hippocampus of Juvenile Mice.

  2026. okt. 1.· Journal of neurochemistry· PUBMED

• Publikáció

  Predictive value of persistent cerebrospinal fluid antibodies at 12 months for long-term clinical outcomes in pediatric anti-NMDAR encephalitis: a retrospective cohort study.

  2026. okt. 1.· Frontiers in immunology· PUBMED

• Publikáció

  Sex-Divergent Patterns in Hippocampal and Cortical NMDA Receptor Density Across the Alzheimer's Disease Continuum.

  2026. szept. 25.· International journal of molecular sciences· PUBMED

• Publikáció

  Thalamofrontal synaptic weakening underlies short-term memory deficits from adolescent NMDAR hypofunction.

  2026. szept. 23.· Science advances· PUBMED

• Publikáció

  A Cell Type-Specific Switch in GluN2D NMDA Receptors Drives Cortical Circuit Hyperexcitability and Sensory-Driven Cortical Synchronization Deficits in a Fragile X Syndrome Model.

  2026. szept. 21.· Biological psychiatry· PUBMED

• Publikáció

  Hippocampal LTP shifts from NMDAR dependence to mGluR/VGCC-supported mechanisms following juvenile status epilepticus in rats.

  2026. szept. 20.· Neuroscience· PUBMED

• Publikáció

  D-Cycloserine ameliorates innate fear deficits in young adult male APP/PS1 mice: Involvement of GluN2B-containing NMDA receptor.

  2026. szept. 19.· Pharmacology, biochemistry, and behavior· PUBMED

• Publikáció

  Nursing care of a pediatric patient with anti-NMDAR encephalitis complicated by secondary epilepsy: A case report.

  2026. szept. 18.· Medicine· PUBMED

• Publikáció

  Mechanisms of NMDA receptor inhibition by fluoroethylnormemantine - comparison with memantine.

  2026. szept. 11.· European journal of pharmacology· PUBMED

• Publikáció

  Curcumin attenuates NMDA Receptor Phosphorylation on Glutamatergic Terminals and Lowers Blood Pressure in Obese Postmenopausal Mice.

  2026. szept. 7.· The Journal of nutrition· PUBMED

• Publikáció

  Ovariectomy reverses maternal immune activation-induced deficits in dopamine and NMDA receptor-mediated regulation of prepulse inhibition in female Long-Evans rats.

  2026. szept. 7.· Schizophrenia research· PUBMED

• Publikáció

  NMDA subunit 2B-selective negative allosteric modulator satoprodil (BI 1569912) as mono- and adjunctive therapy in patients with major depressive disorder: results from two phase 2 randomized, controlled trials.

  2026. szept. 5.· Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology· PUBMED

• Publikáció

  NMDA receptor ablation in medial prefrontal cortex disrupts value updating and reward history integration.

  2026. szept. 1.· Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology· PUBMED

• Publikáció

  Selective mGlu1 Receptor Activation Restores Cortical Inhibitory Tone and Improves Cognitive Performance in a Subchronic Phencyclidine NMDA Hypofunction Model.

  2026. szept. 1.· Biological psychiatry global open science· PUBMED

• Publikáció

  Ferroptosis and NMDA Receptor Activity in Alzheimer's Disease: Implications for Amyloid Pathology and P-Glycoprotein Regulation.

  2026. szept. 1.· Drug development research· PUBMED

• Publikáció

  Structural and mechanistic insights into gating and allosteric modulation of GluN1-GluN3A NMDA receptors.

  2026. aug. 28.· Nature structural & molecular biology· PUBMED

• Publikáció

  A Dual Prediction Error Populations Model of Schizophrenia Spectrum Disorders: Bridging NMDA Hypofunction and Gain Hyperfunction.

  2026. aug. 20.· Schizophrenia bulletin· PUBMED

• Publikáció

  Efgartigimod as a salvage therapy for anti-NMDAR encephalitis patients after first-line treatment failure: a case series.

  2026. aug. 14.· Frontiers in neurology· PUBMED

• Publikáció

  Targeting NMDA Receptor Pathways in Alzheimer's Disease, From Cellular Mechanisms to Treatment Strategies.

  2026. aug. 13.· Current neuropharmacology· PUBMED

• Publikáció

  NMDA receptor subunit-dependent analysis of radiprodil inhibition in neonatal male rat substantia nigra dopaminergic neurons.

  2026. aug. 13.· British journal of pharmacology· PUBMED

• Publikáció

  Development of glutamatergic antipsychotics requires efficient synaptic glutamatergic transmission while preventing NMDA receptor down-regulation and overactivation of extrasynaptic transmission.

  2026. aug. 13.· British journal of pharmacology· PUBMED

• Publikáció

  Corticostriatal glutamate mechanisms underlying beta synchrony and motor deficits via striatal NMDA receptors in Parkinson's disease.

  2026. aug. 11.· EBioMedicine· PUBMED

• Publikáció

  Redox Homeostasis and Oxidative Stress in Schizophrenia: Glutathione-NMDA-Neuroimmune Convergence and a Hypothesis-Generating Iron-Lipid Redox Extension.

  2026. aug. 8.· International journal of molecular sciences· PUBMED

• Preprint

  Sex-divergent trajectories of hippocampal and cortical NMDA receptor density across the Alzheimer's disease continuum.

  2026. aug. 6.· bioRxiv : the preprint server for biology· PUBMED

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