Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Vizsgálat
Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers
2026. nov. 11.· PHASE2 · NOT_YET_RECRUITING· CTGOV
Publikáció
A novel SLTM::RUNX1 acquired during CML progression and the clinical significance of concurrent BCR::ABL1 and RUNX1 rearrangements in Ph-positive leukemia.
2026. okt. 31.· Cancer genetics· PUBMED
Publikáció
RUNX1-ETO oncoprotein levels determine the balance between endothelial reprogramming and pre-leukemic growth in a human ES cell model of AML.
2026. okt. 19.· Cell reports· PUBMED
Publikáció
Hematologic Malignancies With RUNX1::ZFPM2 Translocation: A Case Report and Literature Review.
2026. okt. 16.· EJHaem· PUBMED
Publikáció
Acute monocytic leukemia with t(8;22)(p11;q11)/BCR::FGFR1, trisomy 8, and concurrent RUNX1/STAG2 mutations: A rare case report and literature review.
2026. okt. 10.· Leukemia research reports· PUBMED
Publikáció
RUNX1 aberrations in blast-phase chronic myeloid leukaemia induce the RNA-binding protein SPATS2L, which promotes growth, survival and stress granule assembly.
2026. okt. 9.· Leukemia· PUBMED
Publikáció
Sensitivity to ATR-CHK1 pathway inhibition in MDS/AML is enhanced by SRSF2 mutations and reduced by RUNX1 loss.
2026. okt. 6.· Leukemia· PUBMED
Publikáció
RUNX1 links ATF4-associated stress adaptation to microenvironmental remodeling in POSTN+ fibroblasts during skin fibrosis.
2026. szept. 18.· Burns & trauma· PUBMED
Publikáció
Efficacy and Safety of Azacitidine in Patients With RUNX1::RUNX1T1 Measurable Residual Disease-Positive Acute Myeloid Leukemia After Consolidation Therapy Who Did Not Undergo Allogeneic Hematopoietic Stem-Cell Transplantation.
2026. szept. 18.· Clinical lymphoma, myeloma & leukemia· PUBMED
Publikáció
Concurrent RUNX1::MECOM and RUNX1::PRDM16 Fusions from a Novel Genomic Breakpoint: First Report of a Dual-Fusion Mechanism in Acute Myeloid Leukemia.
2026. szept. 16.· OncoTargets and therapy· PUBMED
Publikáció
Genomic Characterization of ETV6::RUNX1-Positive Childhood B-ALL in a Chinese Cohort: Novel Fusion Partners, Co-Occurring Mutations, and Risk-Stratifying Biomarkers.
2026. szept. 10.· Pediatric blood & cancer· PUBMED
Publikáció
Association Between Mutation Context-Associated RUNX1 Transcriptional States and Immune-Stromal Heterogeneity in Nonsmall Cell Lung Cancer.
2026. szept. 6.· Human mutation· PUBMED
Publikáció
AML1-ETO hijacks a distal enhancer of NAT10 to reprogram glutathione metabolism and sustain leukemia stem cell stemness.
2026. szept. 1.· Proceedings of the National Academy of Sciences of the United States of America· PUBMED
Publikáció
The roles of RUNX1 in megakaryocyte differentiation in myeloid leukemia.
2026. aug. 24.· Leukemia & lymphoma· PUBMED
Publikáció
Somatic RUNX1 exonic deletions in myelodysplastic syndrome: A rare yet high-risk recurrent genetic aberration.
2026. aug. 21.· HemaSphere· PUBMED
Publikáció
Oncogenic DHX15 mutation enhances mitochondrial metabolism and sustains leukemia stemness.
2026. aug. 21.· Leukemia· PUBMED
Publikáció
The Outcomes of Single-unit Unrelated Umbilical Cord Blood Transplantation for Adult Acute Myeloid Leukemia with RUNX1::RUNX1T1 in Multicenter Retrospective analysis.
2026. aug. 19.· Transplantation proceedings· PUBMED
Publikáció
Prognostic Impact of Sequential Measurable Residual Disease and KIT Variant Status in Pediatric Core-Binding Factor Acute Myeloid Leukemia: A Retrospective Multicenter Study of the Taiwan Pediatric Oncology Group.
2026. aug. 19.· Annals of laboratory medicine· PUBMED
Publikáció
Prognostic relevance of RUNX1 mutations at acute myeloid leukemia diagnosis and as measurable residual disease marker before and after allogeneic stem cell transplantation.
2026. aug. 13.· Haematologica· PUBMED
Publikáció
RUNX1 silencing protects against cerebral ischemia/reperfusion injury-induced endoplasmic reticulum stress, inflammation, ferritinophagy and ferroptosis through the CELF2/mTOR axis.
2026. aug. 12.· Toxicology and applied pharmacology· PUBMED
Publikáció
RUNX1-driven endothelial-to-mesenchymal transition contributes to remodelling in LMNA cardiomyopathy.
2026. aug. 11.· European heart journal· PUBMED
Publikáció
RUNX1 upregulation and RUNX1-ETO depletion inhibits survival of t(8;21)-positive leukemia cells.
2026. aug. 3.· Global medical genetics· PUBMED
Publikáció
Psychosocial aspects of RUNX1-familial platelet disorder in adolescents and young adults: "The fear of knowing it could happen sometime down the road".
2026. aug. 1.· Journal of genetic counseling· PUBMED
Publikáció
RUNX1-Driven CPXM1 Transcription Promotes Malignant Phenotypes and EMT in Gastric Cancer Cells.
2026. júl. 31.· Cancer science· PUBMED
Publikáció
CYBRD1 is transcriptionally regulated by RUNX1 and mediates JAK2/STAT3 signaling activation during ovarian cancer progression.
2026. júl. 29.· Oncogenesis· PUBMED
Publikáció
Paris saponin VII promotes TRIP12-mediated SOD1 degradation to synergize with idarubicin in ROS-dependent acute myeloid leukemia cell death.
2026. júl. 29.· Phytomedicine : international journal of phytotherapy and phytopharmacology· PUBMED
Publikáció
EIF4A3-dependent nonsense-mediated decay buffers AML1-ETO9a dosage and modulates outcome in t(8;21) acute myeloid leukemia.
2026. júl. 14.· Leukemia· PUBMED
Publikáció
DHX15 affects AML1-ETO9a splicing together with HNRNPL, RBM33 in AML1-ETO-positive acute myeloid leukaemia.
2026. júl. 12.· British journal of haematology· PUBMED
Publikáció
Targeting RUNX1 protects against diastolic dysfunction in a two-hit mouse model of heart failure with preserved ejection fraction.
2026. júl. 11.· Cardiovascular research· PUBMED
Publikáció
A special multifiber dietary mixture ameliorates Crohn's-like colitis in an IL-10-/- mouse model by promoting treg differentiation through the ETS1/RUNX1/Foxp3 axis.
2026. júl. 3.· European journal of nutrition· PUBMED