Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
HIF-1α/PPAR-γ/SIRT1 axis drives astrocyte senescence and regulates endothelial function via GDNF/NRTN in diabetic retinopathy.
2026. nov. 6.· PloS one· PUBMED
Publikáció
p97 inhibition attenuates cigarette Smoke-Induced lung inflammation and epithelial senescence by Restoring SIRT1 SUMOylation.
2026. nov. 4.· Biochemical pharmacology· PUBMED
Publikáció
Multi-scale computational analysis of MMP9 and SIRT1 regulatory networks and their interaction with curcumin and resveratrol in lung adenocarcinoma.
2026. nov. 3.· In silico pharmacology· PUBMED
Publikáció
Phytochemical investigation and neuroprotective effect of Encephalartos kisambo Faden & Beentje: Regulation of SIRT1, lnc-MALAT1, and vimentin in mice.
2026. nov. 2.· Fitoterapia· PUBMED
Publikáció
Resveratrol Modulates Bone Metabolism Through SIRT1-Mediated NF-κB Inhibition: Molecular Mechanisms and Therapeutic Implications.
2026. nov. 1.· Cell biochemistry and function· PUBMED
Publikáció
SIRT1 Signaling in Alzheimer's Disease: Regulation of Mitochondrial Biogenesis and Therapeutic Implications.
2026. okt. 31.· Pharmacological research· PUBMED
Publikáció
Zederone-calycosin ameliorates psoriasis via the AMPK/SIRT1/PGC-1α pathway: insights from the Astragali Radix-Curcumae Rhizoma herb pair.
2026. okt. 30.· International immunopharmacology· PUBMED
Publikáció
Baicalin alleviates renal interstitial fibrosis by targeting SIRT1/HIF-1α signaling pathway.
2026. okt. 27.· Journal of ethnopharmacology· PUBMED
Publikáció
Stabilization of LTBP2 by SIRT1 promotes EMT and chemosensitivity in cardia gastric adenocarcinoma through TGF-β signaling.
2026. okt. 27.· Oncogene· PUBMED
Publikáció
Hyperglycemia-Induced Loss of Astrocytic Kir4.1 Is Associated with Increased DNMT1 Activity and Altered AMPK/SIRT1 Signaling.
2026. okt. 20.· Cells· PUBMED
Publikáció
Correction: Sinigrin, a bioactive compound from cruciferous vegetables, ameliorates MASLD by activating AMPK/SIRT1/PGC-1α to enhance fatty acid beta-oxidation.
2026. okt. 19.· Food & function· PUBMED
Publikáció
Tirzepatide Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension: Association with the SIRT1/H4K12la/c-Jun Axis.
2026. okt. 19.· Cells· PUBMED
Publikáció
Caffeine and Exercise in Obesity-Associated Brain Aging and Neurodegeneration: Mechanistic Insights into AMPK/SIRT1/PGC-1α, BDNF/TrkB, and NLRP3 Inflammasome Signaling.
2026. okt. 16.· Molecular neurobiology· PUBMED
Publikáció
Research on the Regulatory Effects of Resveratrol on BCG-Induced Autophagy and Apoptosis in Macrophages via Targeting SIRT1.
2026. okt. 15.· Microorganisms· PUBMED
Publikáció
Intermedin attenuates chronic intermittent hypoxia-induced renal fibrosis via SIRT1-mediated inhibition of the NOX4/ROS axis.
2026. okt. 12.· Biochemical pharmacology· PUBMED
Publikáció
The synergistic effects of resveratrol and nicotinamide on cell proliferation, apoptosis, and SIRT1 gene expression in human retinal pigment epithelial cells.
2026. okt. 12.· Tissue & cell· PUBMED
Publikáció
Pseudomonas aeruginosa Pyocyanin Increases Airway Mucin Biosynthesis by SIRT1-Mediated FOXA2 Inactivation.
2026. okt. 6.· International journal of molecular sciences· PUBMED
Publikáció
Therapeutic Window of AAV-SIRT1 Gene Therapy in Mouse Models of Optic Nerve Degeneration.
2026. okt. 5.· Translational vision science & technology· PUBMED
Publikáció
Ferulic acid-mediated selenium nanoparticles attenuate oxaliplatin-induced renal injury in type 2 diabetic rats via modulation of oxidative stress, SIRT1/HMGB1/TLR4 signaling, endoplasmic reticulum stress, and apoptosis.
2026. okt. 4.· Tissue & cell· PUBMED
Publikáció
Icariin Protects Against Mitochondrial Damage and Ferroptosis-Related Injury in Synovial Fibroblast-Like Synoviocytes Through SUMO1-Dependent Regulation of SIRT1.
2026. okt. 1.· IUBMB life· PUBMED
Publikáció
Securidaca inappendiculata Extract Mitigates Joint Damage in Collagen-Induced Arthritis Rats Through Modulation of the SIRT1/HIF-1α/Glycolysis Pathway.
2026. okt. 1.· Pharmacology research & perspectives· PUBMED
Publikáció
Therapeutic Potential of Pioglitazone in a Propionic Acid-Induced Rat Model of Autism Spectrum Disorder: The Role of the SIRT1/PPAR-γ Axis.
2026. okt. 1.· International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience· PUBMED
Publikáció
Statement of Retraction: N6-methyladenosine (m6A) reader IGF2BP2 promotes gastric cancer progression via targeting SIRT1.
2026. okt. 1.· Bioengineered· PUBMED
Publikáció
Design, Synthesis, and Biological Evaluation of Pyrazolyl Thioureas (PTUs) as SIRT1 and SIRT2 Inhibitors.
2026. szept. 28.· ChemMedChem· PUBMED
Publikáció
SIRT1-mediated deacetylation of TRIM21 promotes IRF5 degradation and restrains type I interferon signatures in Sjögren's disease.
2026. szept. 23.· Translational research : the journal of laboratory and clinical medicine· PUBMED
Publikáció
Novel applications of SIRT1 in Chronic Kidney Disease.
2026. szept. 23.· Frontiers in medicine· PUBMED
Publikáció
"Improving the beneficial effects of HDAC8 inhibition by simultaneously activation of SIRT1 in a zebrafish model of Duchenne muscular dystrophy.
2026. szept. 20.· Pharmacological research· PUBMED
Publikáció
Xinmailong Injection Attenuates Doxorubicin-Induced Chronic Heart Failure by Regulating the SIRT1/Caspase-3 Axis and Metabolic Reprogramming: An Integrative Network Pharmacology and Metabolomics Study.
2026. szept. 18.· Current medical science· PUBMED
Publikáció
Agrimol B induces apoptosis and ferroptosis in acute monocytic leukemia by targeting EGFR/ERK1/2 signaling and activating SIRT1.
2026. szept. 17.· Cancer treatment and research communications· PUBMED
Publikáció
Sasca D, Hähnel PS, Szybinski J, et al. SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia. Blood. 2014;124(1):121-133.
2026. szept. 17.· Blood· PUBMED