Új vizsgálatok, publikációk, preprintek és pályázatok ezen a célponton, hónapról hónapra.
Publikáció
ENPP1 inhibits the cGAS-STING pathway to mediate immune evasion in EGFR-TKI-resistant non-small cell lung cancer.
2026. nov. 5.· Cell death and differentiation· PUBMED
Publikáció
Engineered T cell-agonist chimera for logic-gated STING activation and augmented cancer immunotherapy.
2026. nov. 3.· Proceedings of the National Academy of Sciences of the United States of America· PUBMED
Publikáció
Simiao Pill ameliorates collagen-induced arthritis in association with gut-joint axis modulation and attenuation of cGAS-STING signaling.
2026. nov. 3.· Journal of ethnopharmacology· PUBMED
Publikáció
STING-dependent TNF signalling promotes IKKβ-mediated ATG9A phosphorylation and autophagy.
2026. nov. 3.· Nature cell biology· PUBMED
Publikáció
Ferroportin deficiency drives olaparib resistance in ovarian cancer via the cGAS-STING-STAT3 survival axis.
2026. nov. 1.· Clinical and translational medicine· PUBMED
Publikáció
Repurposing the orphan drug nitisinone synergizes with sorafenib to sensitize immunotherapy-refractory MSS-CRC via metabolic stress-driven STING activation.
2026. okt. 30.· Pharmacological research· PUBMED
Publikáció
Cascade-Catalytic MnO2 Nanoreactor Amplifies Oxidative Stress and Activates cGAS-STING Pathway To Remodel the Immunosuppressive Microenvironment of Triple-Negative Breast Cancer.
2026. okt. 28.· ACS applied materials & interfaces· PUBMED
Publikáció
Therapeutic effect of quercetin on airway remodeling of ovalbumin-induced asthmatic mice via inhibition of the mtDNA-cGAS-STING pathway.
2026. okt. 27.· Molecular and cellular biochemistry· PUBMED
Publikáció
The Tango of cGAS-STING and Phagocytosis in Disease: From Molecular Mechanisms to Pharmacological Targeting.
2026. okt. 24.· Drug design, development and therapy· PUBMED
Publikáció
Targeting histone methylation with ROS nanoparticles delivering PARPi prodrugs to amplify the stimulation of cGAS-STING for immunotherapy in ovarian cancer.
2026. okt. 23.· Materials today. Bio· PUBMED
Publikáció
Targeting STING to attenuate autophagy-mediated airway remodeling in asthma.
2026. okt. 23.· Molecular and cellular biochemistry· PUBMED
Publikáció
Engineered mitochondria-derived vesicles suppress colorectal cancer through metabolic reprogramming and mtDNA-cGAS-STING signaling.
2026. okt. 22.· Cellular signalling· PUBMED
Publikáció
CREBBP loss drives immune evasion by epigenetically silencing STING and MHC-I in small cell lung cancer.
2026. okt. 21.· Science advances· PUBMED
Publikáció
Anti-PD-L1 antibody-coated metal-organic framework for targeted PTPN2 Inhibitor delivery and enhanced immunotherapy of head and neck squamous cell carcinoma via cGAS-STING activation.
2026. okt. 20.· International journal of pharmaceutics: X· PUBMED
Publikáció
[40 Hz flicker light stimulation suppresses STING signaling to improve cognitive dysfunction in mice with Parkinson disease].
2026. okt. 20.· Nan fang yi ke da xue xue bao = Journal of Southern Medical University· PUBMED
Publikáció
Context-dependent cGAS-STING signaling in inflammatory bowel disease: cell specificity, lesion state, and therapeutic windows.
2026. okt. 20.· Frontiers in immunology· PUBMED
Publikáció
Context-dependent cGAS-STING signaling in solid tumors: biological determinants, clinical implications, and biomarker-guided therapeutic strategies.
2026. okt. 19.· Frontiers in immunology· PUBMED
Publikáció
Immunotoxicological mechanism of a dual-targeted nanocomposite: Mitochondrial stress-driven cGAS-STING activation in lung cancer.
2026. okt. 16.· Colloids and surfaces. B, Biointerfaces· PUBMED
Publikáció
Developing a Better Hepatocellular Carcinoma Treatment: AlEu MOF Nanoparticles Enhance Microwave Thermal Ablation and Synergistically Activate the cGAS-STING Pathway.
2026. okt. 16.· International journal of nanomedicine· PUBMED
Publikáció
Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging.
2026. okt. 15.· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publikáció
Single-Cell Analysis of Residual Esophageal Squamous Cell Carcinoma after Neoadjuvant Immunochemotherapy Reveals TFAM-Mediated Immunoregulation in Dendritic Cells.
2026. okt. 15.· Cancer research· PUBMED
Publikáció
Metabolic Competition-Driven Antitumor Immunity of glpX-Deficient Engineered Salmonella via Glucose Deprivation and STING Activation in Bladder Cancer.
2026. okt. 15.· Cancer communications (London, England)· PUBMED
Publikáció
NAD+ Attenuates Neuroinflammation in Ischemic Stroke by Suppressing the cGAS- STING Pathway via Mitochondrial Homeostasis Restoration.
2026. okt. 14.· Molecular neurobiology· PUBMED
Publikáció
CCNE1 overexpression drives a cGAS-STING-dependent interferon response and sensitizes HRD-positive ovarian cancer to immune checkpoint blockade.
2026. okt. 14.· Journal for immunotherapy of cancer· PUBMED
Publikáció
Targeting Macrophage STING O-GlcNAcylation via Small-Molecule Allosteric Modulation for Psoriasis Therapy.
2026. okt. 14.· Advanced science (Weinheim, Baden-Wurttemberg, Germany)· PUBMED
Publikáció
Polygonatum sibiricum polysaccharide attenuates BMSC senescence by inhibiting NCOA4-mediated ferritinophagy.
2026. okt. 14.· Pharmaceutical biology· PUBMED
Publikáció
The cGAS-STING pathway in metabolic dysfunction-associated steatotic liver disease: mechanistic insights and therapeutic opportunities.
2026. okt. 13.· Frontiers in pharmacology· PUBMED
Publikáció
The cGAS-STING signaling axis in Type 2 diabetes-associated cognitive decline: from mitochondrial DNA sensing to neurodegeneration.
2026. okt. 12.· Acta diabetologica· PUBMED
Publikáció
CISD1 suppresses COPD inflammation by recruiting ubiquitinated STING and altering macrophage metabolism.
2026. okt. 12.· Respiratory research· PUBMED
Publikáció
Stimulator of Interferon Genes (STING) Agonist-Loaded Copper-Based Nanoparticles for B7-H3 Blockade-Enhanced Chemodynamic-Immunotherapy of Ovarian Cancer.
2026. okt. 10.· International journal of nanomedicine· PUBMED