Taking people in Dánia4. fázis
The OPTIMIST study
Key facts
- Where
- Aalborg, Aarhus N, Copenhagen Nv, Hvidovre és Odense C, DániaSee the 5 sites
- Phase
- 4. fázis
Where in Dánia
- Aalborg University HospitalAalborg, DániaTaking people
- Aarhus UniversitetshospitalAarhus N, DániaTaking people
- Bispebjerg HospitalCopenhagen Nv, DániaTaking people
- Hvidovre HospitalHvidovre, DániaTaking people
- Odense University HospitalOdense C, DániaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Aarhus University Hospital
- Trial code
- EU 2023-505940-20-00
- Record updated
- 2026. október 5.
- Original description
The main objective of the OPTIMIST study is to identify the optimal use of romosozumab for the treatment of osteoporosis by investigating 3 different treatment strategies.Read full original descriptionShow less
The Optimised use of Romosozumab Study
The main objective of the OPTIMIST study is to identify the optimal use of romosozumab for the treatment of osteoporosis by investigating 3 different treatment strategies.
Inclusion: postmenopausal women; Osteoporosis defined as BMD T-score < -2.5 at spine, total hip or femoral neck; Osteoporotic fracture at spine, hip, pelvis, forearm, or humerus within 3 years after the age of 50 years.
Exclusion: Ongoing treatment with glucocorticoids; Metabolic bone disease; Known disorders affecting bone metabolism; Estimated glomerular filtration rate (eGFR) < 35 ml/min; Osteoporosis treatment within the last 5 years; Contraindications or intolerance to romosozumab or zoledronate.