The role of intra-abdominal pressure and point of care ultrasound to guide decongestive therapy in Heart Failure (ABDOPOCUS-HF)
Key facts
- Where
- A Coruna, Avilés (Asturias), Girona, Lleida, Madrid, Majadahonda, Málaga, Murcia, San Sebastián de los Reyes, Sevilla, Tudela, Valencia és Zaragoza, SpanyolországSee the 15 sites
- Phase
- 3. fázis
Where in Spanyolország
- Complejo Hospitalario Universitario Juan CanalejoA Coruna, SpanyolországTaking people
- Hospital San Agustín de AvilésAvilés (Asturias), SpanyolországTaking people
- Hospital Universitari de Girona Doctor Josep TruetaGirona, SpanyolországTaking people
- Hospital Universitari Arnau De Vilanova De La Gerencia Territorial De LleidaLleida, SpanyolországTaking people
- Hospital Clínico San CarlosMadrid, SpanyolországTaking people
- Hospital Universitario Infanta LeonorMadrid, SpanyolországTaking people
- Hospital Universitario Ramón y CajalMadrid, SpanyolországTaking people
- Hospital Universitario Puerta de Hierro de MajadahondaMajadahonda, SpanyolországTaking people
- Hospital Universitario Virgen de la VictoriaMálaga, SpanyolországTaking people
- University Clinical Hospital Virgen De La ArrixacaMurcia, SpanyolországTaking people
- Hospital Universitario Infanta SofiaSan Sebastián de los Reyes, SpanyolországTaking people
- Hospital Universitario Virgen De La MacarenaSevilla, SpanyolországTaking people
- Hospital Reina SofíaTudela, SpanyolországTaking people
- Consorcio Hospital General Universitario de ValenciaValencia, SpanyolországTaking people
- Hospital Clinico Universitario Lozano BlesaZaragoza, SpanyolországTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fundacion Instituto De Investigacion Sanitaria Aragon
- Trial code
- EU 2024-512901-22-00
- Record updated
- 2026. május 25.
- Original description
To evaluate the complete resolution of congestion (ADVOR scale) after the first 72 hours of intravenous diuretic treatment on the hospital ward, between the standard treatment group and the intervention group (intra-abdominal pressure and ultrasound)Read full original descriptionShow less
Utility of intra-abdominal pressure and clinical ultrasound for guiding diuretic treatment in patients with acute heart failure
To evaluate the complete resolution of congestion (ADVOR scale) after the first 72 hours of intravenous diuretic treatment on the hospital ward, between the standard treatment group and the intervention group (intra-abdominal pressure and ultrasound)
Inclusion: Men or women over 18 years of age; Diagnosis of HF based on the latest HF guidelines published in 2022; NT-proBNP > 1000 pg/mL or BNP > 250 pg/mL; Bladder catheterization in order to perform intra-abdominal pressure measurement; Intravascular or mixed pattern of congestion, defined as the presence of one or more clinical signs of congestion (edema, ascites and/or pleural effusion); Signature of the informed consent.
Exclusion: Patients receiving renal replacement therapy (ultrafiltration or peritoneal dialysis); Renal transplant recipients; Previous history of hypersensitivity to hydrochlorothiazide or furosemide; Heart rate at admission > 170 beats per minute (bpm); Acute myocardial ischemia; Patients with recent cardiac surgery (last year) or cardiac transplant recipients; Need for inotropic support to maintain adequate cardiac and/or renal output; Serum hemoglobin < 9 g/dL; Patient with stay in the internal medicine department > 24 hours; Systolic blood pressure at admission < 100 mmHg; Cardiogenic shock; Patients whose origin is the Intensive Care Unit; Pregnancy or lactation; Absence of sufficient clinical congestion (ADVOR score = 0 at the time of randomization); Patient refusal to participate in the clinical trial; Inability or contraindication to bladder catheterization.