Vitamin D Supplementation to increase free testosteron in Type 2 Diabetes Mellitus men: a Placebo-controlled Randomized Clinical Trial
Key facts
- Where
- Jette, BelgiumSee the site
- Phase
- 2. fázis
Where in Belgium
- UZ BrusselJette, BelgiumTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- UZ Brussel
- Trial code
- EU 2024-514834-19-00
- Record updated
- 2026. október 27.
- Original description
To increase low free testosteron in men with T2D by vitamin D supplementation. Evaluation of the effect of vitamin D supplementation on the free testosteron level in men with type 2 diabetes and low testosteron level.Read full original descriptionShow less
Vitamin D Supplementation to increase free testosterone in Type 2 Diabetes Mellitus men: a Placebo-controlled Randomized Clinical Trial
To increase low free testosteron in men with T2D by vitamin D supplementation. Evaluation of the effect of vitamin D supplementation on the free testosteron level in men with type 2 diabetes and low testosteron level.
Inclusion: Vitamin D < 75 nmol/L; Caucasian men; Age: 18 - 65 years; BMI < 40 kg/m²; Type 2 diabetes mellitus; HbA1c ≤ 64 mmol/mol, ( 8%); Total testosteron < 11nmol/L.
Exclusion: Any supplementation containing vitamin D alone or in combination within 2 months before the screening visit and during the study; The use of medications affecting bone turnover (cholecalciferol, vitamin K, bisphosphonates, anti-epileptic medication, corticosteroid use, heparin); Known bone disease (osteoporosis, Paget disease, primary hyperparathyroidism); Chronic liver failure defined as GOT/GPT > 2N; A history of orchidectomy; Chronic renal failure defined as eGFR less than 60 mL/min/1.73 m2 for three or more months; Hypocalcaemia defined as calcium levels below lower limit of normal range < 2.10 mmol/L; Hypomagnesaemia defined as magnesium < 0.65 mmol/L; Hypoalbuminemia defined as albumin < 3 g/dL; Hypercalcemia defined as > 2.55 mmol/L; The use of Testosteron supplementation; BMI > 40 Kg/m²; Neuroleptic treatment.