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PET-DOPA Metabolic Detection and Characterization of Untreated Brain Metastases of Bronchial, Breast and Melanoma Cancer

Key facts

Where
Angers, Pontoise és Saint-Herblain Cedex, FranciaországSee the 4 sites
Phase
2. fázis

Where in Franciaország

  • Centre Hospitalier Universitaire D'AngersAngers, FranciaországNo longer taking part
  • Institut de Cancerologie de L'OuestAngers, FranciaországNo longer taking part
  • Hôpital NOVOPontoise, FranciaországNo longer taking part
  • Institut De Cancerologie De L OuestSaint-Herblain Cedex, FranciaországNo longer taking part

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Trial details

Who runs it
Institut De Cancerologie De L Ouest
Trial code
EU 2024-515850-26-00
Record updated
2024. december 10.
Original description
To define the sensitivity of PET-DOPA for the detection of newly diagnosed untreated brain metastases (breast, lung, melanoma) on MRI measuring at least 5 mm in diameterRead full original descriptionShow less

PET-DOPA Metabolic Detection and Characterization of Untreated Brain Metastases of Bronchial, Breast and Melanoma Cancer (DOPACER)

To define the sensitivity of PET-DOPA for the detection of newly diagnosed untreated brain metastases (breast, lung, melanoma) on MRI measuring at least 5 mm in diameter

Inclusion: Histologically proven primary cancer (non-small cell lung, breast or melanoma); Presence of brain metastasis(s) visualized on MRI, with at least 1 measuring more than 5 mm; Age ≥ 18 years.

Exclusion: Previous brain surgery for brain metastasis or glial tumor; Systemic therapy (chemotherapy, targeted therapy, immunotherapy) modified in the 6 weeks preceding the PET-DOPA scan,; New anti-tumor treatment (excluding corticosteroids) started between the discovery of CD and the performance of the PET-DOPA scan; History of cerebral irradiation; Other concomitant cancer, or history of cancer in the 5 years preceding the patient's inclusion in the protocol other than basal or squamous cell carcinoma; Pregnant, likely to be pregnant or breastfeeding.

EU CTIS 2024-515850-26-00