The effect of Oxygen sUppleTion on vascular resistance and FLOW: the OUTFLOW study
Key facts
- Where
- Nijmegen, HollandiaSee the site
- Phase
- 4. fázis
Where in Hollandia
- Stichting Radboud Universitair Medisch CentrumNijmegen, HollandiaToborzás még nem indult
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Stichting Radboud universitair medisch centrum
- Trial code
- EU 2024-516279-34-00
- Record updated
- 2024. október 31.
- Original description
To objectify the effect of high-concentration (100%) oxygen suppletion on coronary, pulmonary and systemic haemodynamics, and the chronological sequence of these effectsRead full original descriptionShow less
To objectify the effect of high-concentration (100%) oxygen suppletion on coronary, pulmonary and systemic haemodynamics, and the chronological sequence of these effects
Inclusion: Subject ≥18 years of age; Subject planned for clinically indicated: 1. CFT demonstrating microvascular dysfunction; or 2. RHC (and LHC) for suspected PH; or 3. RHC (and LHC) as a part of HTx or LVAD screening; No obstructive coronary artery disease (defined as ≤50% visual stenosis and/or negative FFR/iFR/RFR); Able and willing to provide informed consent.
Exclusion: Clinically indicated treatment with oxygen; Known history of chronic obstructive pulmonary disease GOLD IV; Known moderate and severe valvular disease; Contrast allergy; Complications during clinically indicated invasive heart catheterization; Estimated glomerular filtration rate of <30ml/min; Pacemaker in situ; Active pregnancy.